Has anyone had monoclonal antibody treatment for COVID infection?

Posted by ktgirl @ktgirl, Nov 23, 2021

Has anyone here had this treatment and did you have any side effects from it. There seem to be a lot of side effects.

Interested in more discussions like this? Go to the Post-COVID Recovery & COVID-19 Support Group.

@connie1977

Hi, I am one of the individuals you asked for comments on our experience with monoclonal antibody treatments. My husband and I received the bamlanivimab infusion this past January. For us, we feel, it was a life saver. Our symptoms were fatigue, fever, severe aches, respiratory problems, nausea, and others. We went into the treatment center; the infusion took one 1 and then 1 hour of observation. We both felt 90% better when we walked out. The only systems that remained (for a few more days) were fatigue and very few aches. I had been experiencing serious breathing problems; I was on the verge of contacting my doctor about going to the hospital when I received the infusion. I strongly encourage anyone (within the 10 days window of symptoms) to contact your doctor's office so receive the information of when and where to go. We are very happy we had the opportunity to receive it. It is a shame that knowledge of the infusions are so limited and so many people did not have the opportunity to receive this treatment.

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I called to get the antibodies treatment at day 3 and didn't hear back from them. I'm at day 6 now and wonder if it's too late. I've heard they lose their potency the more days you wait. Being thanksgiving today I can't get a hold of anyone.

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@colleenyoung

@jrg200911, Dr. Ganesh wrote about medications that may help with long haul COVID symptoms, as well as listing those that have no evidence of being effective. You can see the list here:

- Post-COVID Syndrome and Medications https://connect.mayoclinic.org/blog/post-covid-recovery/newsfeed-post/post-covid-syndrome-and-medications/

Fifteen months is a long time. Have you been or considered attending a post-COVID rehab program that uses multi-faceted approach to recovery?

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The timing of my COVID diagnostics (PCR and Antibody) all rendered NEGATIVE results to my presumed asymptomatic acute infection. It wasn’t until nearly 12 months post symptom onset I received a POSITIVE result to the T-Detect t-cell test. Until that time I was mostly dismissed by my doctors, especially since all tests run (inc. multiple labs, ECHO, Cardiac Stress Test, Pulmonary Function Test) have returned normal range results. Even the local Post COVID Clinic staff, seen before the T-Detect POSITIVE, would not render a long haul diagnosis. Very frustrating and confusing for me since, by all accounts I have read, I am a textbook case for Long Haul COVID…

Literally overnight, from 9/10/2020 to 9/11/2020, I went from trim, healthy and active with no comorbidities, taking no prescription medications, walking 3-7 miles per day, to suffering shortness of breath; dizziness; chest pain/pressure; brainfog; fatigue; heart racing/palpitations/rate spikes and dips (up to 200bpm/down to mid-40bpm) with little to no exertion - many times while sitting, with nausea, full body flushes preceding these “episodes”; headaches; ribcage soreness, visual changes… overnight. My entire bag-o-symptoms are not always present together nor to the worst degree, but have been always everyday in some combination to varying degrees of severity since onset 9/11/2020. With any level of activity I risk a “crash” involving increase of severity of any or all symptoms lasting sometimes for days.

In the sea of information and mis-information crashing in waves from the medias, I have tried to do my own research to find ways to improve. Not wanting to self-diagnose nor self-medicate, I have sought out legitimate sources and pathways to wellness. For lack of a better recommendation, both my GP and neurologist have referred me to the Mayo Clinic. I am in the process of applying for help through your COVID Activity Rehabilitation Program (CARP) being administered only through the Rochester, MN clinic location. I have yet to hear back to coordinate a plan going forward.

I have also found Dr. Noah Greenspan of New York’s Pulmonary Wellness Foundation who has been centering efforts on COVID LongHaul research and treatment. They have made available free online access to their 6-week “Pulmonary Boot Camp” video reactivity program which incorporates breathing exercises with a gradual increase in activity over the 6 week cycle. I’m just getting started with the program so have no reports yet for effectiveness. I am hopeful.

Pulmonary Wellness Foundation
Dr. Noah Greenspan, PT, DPT, CCS, EMT-B
10 East 38th St, 10th Floor
New York, NY 10016
212-921-0214
breathe@pulmonarywellness.org
http://www.pulmonarywellness.org

There are still so many unknowns as we all navigate through COVID. I’m willing to serve as a guinea pig of sorts if it ultimately leads to the health and well-being of others. In the meantime, I have run to my Lord, in whom is my trust, for refuge in troubled and joyous times. All is well with my soul.

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@jrg200911

Interested in knowing, too.

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No. But the 1800 mg of Darzalex helped ward it off. (Monoclonal) monthly.

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My husband and I (both in our 70’s) were both fully vaccinated. I developed break-through symptoms/tested positive 3 days after attending a funeral, gave it to my husband. We both had the IV monoclonal antibodies treatment at our local hospital’s ER. The infusion took about 25 minutes, then had to wait for an hour for any side effects (none at all). My husband received it on Day 2 of symptoms, he recovered with very mild symptoms in 2-3 days, I had it on Day 10, very quick recovery.

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Hello all,
I’m 70,I’ve been all my life an outdoor man,fishing,camping,hiking,I’ve been bitten or stung by different insects or bees and never I had allergic reaction to anything !
Until two days ago when I’ve been stung by a bee,when ,after 10 minutes I developed a painful skin red rash,after approx.30 min.sweating,headache,loss of power,seconds to collapsing!
I took an antihistamine,no help,I ended up at the emergency hospital.They told me that the second episode would be more severe and dangerous!
Now I’m scared to go outside,to have shellfish,nuts, etc.
I had my last Covid-19 jab in august 2021.
Could be any connection?,did my immune response went in different direction ? I don’t know what to believe any more !
Did anyone experienced the same situation?

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@ion

Hello all,
I’m 70,I’ve been all my life an outdoor man,fishing,camping,hiking,I’ve been bitten or stung by different insects or bees and never I had allergic reaction to anything !
Until two days ago when I’ve been stung by a bee,when ,after 10 minutes I developed a painful skin red rash,after approx.30 min.sweating,headache,loss of power,seconds to collapsing!
I took an antihistamine,no help,I ended up at the emergency hospital.They told me that the second episode would be more severe and dangerous!
Now I’m scared to go outside,to have shellfish,nuts, etc.
I had my last Covid-19 jab in august 2021.
Could be any connection?,did my immune response went in different direction ? I don’t know what to believe any more !
Did anyone experienced the same situation?

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Wow, those reactions are scary - and they often come on suddenly, with no prior hint...this sounds like an allergic reaction to a bee, or more likely a wasp sting. For some reason, these tend to be more prevalent in the fall, maybe the critters are more aggressive and inject more venom?

The allergic reaction can happen at any time in one's life, even if there has never been one in the past. My Mom collapsed from a wasp sting on the beach at age 76, and the paramedics who caught the call were insistent it was a stroke, due to her age and no prior history of reaction to stings. If my sister, an urgent care nurse wasn't there, and had not badgered them to treat her with epinephrine, she would probably have died.

Please understand that an allergy to one substance does not automatically mean you are allergic to others, so unless you have reacted to one of the other substances you mentioned, you need not fear them. For example, I am highly allergic to bee stings and tree nuts, but I can eat shellfish and peanuts all day long!

Did the ER suggest you see your primary doctor to get an EpiPen to have on hand for possible future emergencies? Or to be tested for other possible allergies?

Two things to note - EpiPens can be expensive, but there are coupons and other help in paying for them, and they can save your life. IF you carry them with you when outdoors. Mine and my daughter's are always with us - in purse, pocket, backpack - to use on a moment's notice.

Do you have an appointment scheduled with your doc?
Sue

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@sueinmn

Wow, those reactions are scary - and they often come on suddenly, with no prior hint...this sounds like an allergic reaction to a bee, or more likely a wasp sting. For some reason, these tend to be more prevalent in the fall, maybe the critters are more aggressive and inject more venom?

The allergic reaction can happen at any time in one's life, even if there has never been one in the past. My Mom collapsed from a wasp sting on the beach at age 76, and the paramedics who caught the call were insistent it was a stroke, due to her age and no prior history of reaction to stings. If my sister, an urgent care nurse wasn't there, and had not badgered them to treat her with epinephrine, she would probably have died.

Please understand that an allergy to one substance does not automatically mean you are allergic to others, so unless you have reacted to one of the other substances you mentioned, you need not fear them. For example, I am highly allergic to bee stings and tree nuts, but I can eat shellfish and peanuts all day long!

Did the ER suggest you see your primary doctor to get an EpiPen to have on hand for possible future emergencies? Or to be tested for other possible allergies?

Two things to note - EpiPens can be expensive, but there are coupons and other help in paying for them, and they can save your life. IF you carry them with you when outdoors. Mine and my daughter's are always with us - in purse, pocket, backpack - to use on a moment's notice.

Do you have an appointment scheduled with your doc?
Sue

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Thank you Sue,yes I have appointment with an allergy specialist and I intend to have all the tests.
It’s scary,it could happen any time without warnings and you can’t do anything!

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@ion

Thank you Sue,yes I have appointment with an allergy specialist and I intend to have all the tests.
It’s scary,it could happen any time without warnings and you can’t do anything!

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Please don't feel that you are powerless in the face of such an allergy.

If you test seriously allergic to any substance, they will teach you about how to respond. Wr have lived with dangerous allergic reactions for 30 years, and managed them all. The keys are knowing what to do, having your meds on your person, and responding immediately. Also teaching people around you.
Please let me know what you learn from the testing.
Sue

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@sueinmn

Please don't feel that you are powerless in the face of such an allergy.

If you test seriously allergic to any substance, they will teach you about how to respond. Wr have lived with dangerous allergic reactions for 30 years, and managed them all. The keys are knowing what to do, having your meds on your person, and responding immediately. Also teaching people around you.
Please let me know what you learn from the testing.
Sue

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Thank you again for your good advice,and I will let you know what’s going to be with the allergy ( Phd) specialist.

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@centre

My husband and I (both in our 70’s) were both fully vaccinated. I developed break-through symptoms/tested positive 3 days after attending a funeral, gave it to my husband. We both had the IV monoclonal antibodies treatment at our local hospital’s ER. The infusion took about 25 minutes, then had to wait for an hour for any side effects (none at all). My husband received it on Day 2 of symptoms, he recovered with very mild symptoms in 2-3 days, I had it on Day 10, very quick recovery.

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Are either of you immunosuppressed?

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