John Hopkins Webinar on transplant recipients and vaccines

Posted by bosco17 @bosco17, Mar 24, 2021

They said after first shot 17 out of 800+patients had only a minimal antibody reaction .Also being on mycophelonate reduces effect of vaccines.WHATS GOING ON ??????

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@jeanne5009

I got a letter so I don't know where to look.

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I’m on iPhone. So here is a Quickie: scroll back to May 20 in this discussion. You will see the link that @nanmargaret posted.

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@nanmargaret

Yes, I listened again to Dorry Segev's response to 3rd dose question at approx. 33:00-39 mins.
- 3rd doses for tx patients have been approved in France
- 3rd doses NOT approved here, but some people are receiving them, he doesn't know how
- IF you have or plan to get a 3rd and are in the study, a "real world observational study", they want to follow whatever is happening with study participants so please let them know date and they would like to test you before and after
- ALWAYS GET APPROVAL for additional vaccine doses or changes to dosing of immunosuppressants with your transplant doctors.

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@nanmargaret I had portal communication with my transplant center, Mass General, yesterday. I mentioned this along with a couple of other things and they said they are following CDC guidelines and when it gets approved by CDC they will notify their transplant recipients. That actually has me somewhat hopeful because I think CDC tends to act faster than MGH does. They still have not approved the shingles vaccine for transplant recipients!

Speaking of the shingles vaccine, I have wondered if that too is less effective on patients who are immunocompromised. It's been on my mind a lot recently because my sister-in-law has had a terrible case of shingles which even landed her in the hospital for five days. She's been battling it since March and is finally getting better. My husband also had shingles in April but his case was very mild.
JK

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@contentandwell

@nanmargaret I had portal communication with my transplant center, Mass General, yesterday. I mentioned this along with a couple of other things and they said they are following CDC guidelines and when it gets approved by CDC they will notify their transplant recipients. That actually has me somewhat hopeful because I think CDC tends to act faster than MGH does. They still have not approved the shingles vaccine for transplant recipients!

Speaking of the shingles vaccine, I have wondered if that too is less effective on patients who are immunocompromised. It's been on my mind a lot recently because my sister-in-law has had a terrible case of shingles which even landed her in the hospital for five days. She's been battling it since March and is finally getting better. My husband also had shingles in April but his case was very mild.
JK

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That’s an interesting question…same thing with Hep A & B, flu and other vaccinations. I was required to get Zoster, Hep, and a couple others prior to transplant.

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@athenalee

That’s an interesting question…same thing with Hep A & B, flu and other vaccinations. I was required to get Zoster, Hep, and a couple others prior to transplant.

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@athenalee To my mind, it makes sense. If the Covid vaccine is less effective then why wouldn't the others be? Of course I really know virtually nothing about the composition of these various vaccines so maybe the Covid ones are unique.
JK

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@jeanne5009

Thank you...hope you are well!

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@jeanne5009, So you are still waiting. I hope that you are feeling okay and that your current low oxygen and the tests will provide some answers a hopeful solution. I know that you have been quite active, in spite of your liver failure. Is this current blood / oxygen slowing you down?
That is fantastic that you were contacted about a clinical trial! Is this with Johns Hopkins? I notice that the trial will go on for a year. This gives all of us an idea of how much different information is being collected and how long it might take for the researchers (and us) to know the answers to our questions about our protection from Covid. Thank you for participating.

You asked about how I am. Well, I just completed my annual evaluation. It has been 12 years for me and my transplant. I am happy to say that my liver and kidney are happy.

I look forward to visiting with you in some of the transplant discussions.
I invite you, and all members to learn more about the new features on Mayo Clinic Connect by following this blog - About Connect: Who, What & Why https://connect.mayoclinic.org/blog/about-connect/

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@rosemarya

@jeanne5009, So you are still waiting. I hope that you are feeling okay and that your current low oxygen and the tests will provide some answers a hopeful solution. I know that you have been quite active, in spite of your liver failure. Is this current blood / oxygen slowing you down?
That is fantastic that you were contacted about a clinical trial! Is this with Johns Hopkins? I notice that the trial will go on for a year. This gives all of us an idea of how much different information is being collected and how long it might take for the researchers (and us) to know the answers to our questions about our protection from Covid. Thank you for participating.

You asked about how I am. Well, I just completed my annual evaluation. It has been 12 years for me and my transplant. I am happy to say that my liver and kidney are happy.

I look forward to visiting with you in some of the transplant discussions.
I invite you, and all members to learn more about the new features on Mayo Clinic Connect by following this blog - About Connect: Who, What & Why https://connect.mayoclinic.org/blog/about-connect/

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I'm guessing my learning curve is starting over....yikes!
Sometimes my brain doesn't want to get technical...I will give it my best
shot!
Super that you are doing well after all these years...so much hope for so
many..
This breathing thing is new. I was thinking it was asthma but maybe not. If
it is hepatopulmonary syndrome that will push me up onto the hot list
maybe. Going to the local pulmonologist in Sarasota Tues.....we will see.
Good to be thru the Covid crunch but not out as much as I would like. My
friend Gary is a clean year out of his Whipple...thank you God!
The 86 year old man I have lived with was just diagnosed with a bowel
blockage. He is losing weight, jaundiced, and holding on until the EUS
which is the 28th.That is the 1st opening the Gastro Dr. has.....
After Covid, everyone needs an operation! He had a triple bypass 20 yrs ago
and is on his 3rd pacemaker. Diabetes 2 as well.
This will keep us busy and I am sure I will be asking for prayers and
advice for Warren and me.
Stay well, stay close....

Here' s to new challenges!!

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@contentandwell

@athenalee To my mind, it makes sense. If the Covid vaccine is less effective then why wouldn't the others be? Of course I really know virtually nothing about the composition of these various vaccines so maybe the Covid ones are unique.
JK

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I did a quick search this morning and found the attached article that does indicate that transplant people do get a good immune response to the Shingrix vaccine. The study was done on kidney transplant people on a range of immunosuppressive therapies.

Shared files

ciz177 (ciz177.pdf)

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Next John Hopkins Webinar on COVID-19 Antibody Testing of Recipients of Solid Organ Transplants (IRB00248540) being led by the transplant team at Johns Hopkins.

1-hour live webinar on Thursday, July 8, 2021, at 1:00PM EDT to share our updated findings and answer questions.

Please register here: https://jhjhm.zoom.us/webinar/register/WN_Pr8grO9lSp2ojJM5mk8OXw

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@athenalee

Next John Hopkins Webinar on COVID-19 Antibody Testing of Recipients of Solid Organ Transplants (IRB00248540) being led by the transplant team at Johns Hopkins.

1-hour live webinar on Thursday, July 8, 2021, at 1:00PM EDT to share our updated findings and answer questions.

Please register here: https://jhjhm.zoom.us/webinar/register/WN_Pr8grO9lSp2ojJM5mk8OXw

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I want to call your attention to the next Johns Hopkins Webinar on COVID-19 Antibody Testing of Recipients of Solid Organ Transplants (IRB00248540) being led by the transplant team at Johns Hopkins. You can access the link and register thru the link that @athenalee has shared.

Everyone is welcome.
@jerrynord, @kedwards73, @livertrex, @contentandwell, @luckonetj, @nanmargaret, @terry14, @pdennis, @danab, @estrada53, @nanmargaret,@bosco17, @kohlgryl079, @zon, @snorris, @luckonetj, @livertrex, @bellini, @scottij
Let's meet here after the webinar and share what we have learned, and how we can support each other.

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