Switching to Trintellix or Low Dose Naltrexone (LDN)

What is TMS?

@elwoodsdad Thanks for your input.

@kelster69 You might look at @elwoodsdad April post on her experience with Trintellix.

Elwoodsdad says be very careful. My experience was not good, expensive, and made day to day living very difficult...My psychiatrist tapered me off Trintellix, and put me on Prozac, an old reliable. Things are good. I have dysthymia, so I always have varying degrees of depression and anxiety playing in the background, but life is much better. Now, this COVID-19 needs to be dealt with...Absolutely bizarre. Trintellix works well when it works. When it doesn’t, not such a good experience.

Ok, thank you, @elwooodsdad. I appreciate you sharing your experiences.

Marjou, I apologize for the delayed response. TMS is Transcranial Magnetic Stimulation, where a coil is hooked up to the part of your brain that controls mood. I started it just this week. It's a 5-week commitment. I have no idea if it's working yet.

Hello to elwoodsdad, as well as the entire community here. I did end up trying Trintellix the day after I wrote my previous post. I was on 5 mg. for 3 weeks, and have been on 20 mg. for 1 1/2 weeks. I sometimes feel a bit better, but still have bad depressive bouts. I want to stop taking it, but I am so impulsive, I am trying to wait until I speak with my psychiatrist in 6 days before I make a decision. I feel like it should have helped me by now. It's so hard to tolerate these depressive, suicidal feelings (I had them before I started the Trintellix, also.)
I also started TMS this week as well as 2 ketamine infusions. So if I do ever feel better, I don't know which method will have worked. The Trintellix causes nausea for sure; I finally tolerated the 5mg but now on 10 mg. I have to take Zofran every morning with the 10 mg pills. I also have had some skin rash but not too bad. I just don't know what to do anymore. I don't know if the Trintellix is making things worse, when my other therapies could be working, or if I'd be even more suicidal off of it. If anyone has anything to add, it'd be much appreciated. I don't see anything positive about Trintellix on this thread. That probably tells me something.

@kelster69 Thanks for getting back to me. Years back I had heard of TMS but very cost prohibitive for me $10,000/per treatment and not covered by insurance. Ketamine has been suggested but long distance, cost, side effects, and insurance issues not viable solution for me. Best of luck to you.

@alamogal635- It's been ages since you last posted. I hope that you are well. I miss your wisdom and comforting words. How have you been?

Despite the high heat of Texas--we really have high heat in August, I've been doing well. I keep up with the posts on this site, but just haven't gotten around to replying to them. Am pretty homebound due to the high level of Corona Virus-19. However, with my four furbabies ( doggies) there is never a dull moment. Actually i have a really bad lower back and it has been troublesome. That's another story, but such is life. WIll have a CY scan as another follow up--6 months in September and a meeting the next week with my oncologist. NOt a whole lot fo write about, but I've been keeping up with you all and am so glad to hear from you. I Will try and write more often. For now, all is well and I send everyone my best and prayers for whatever your needs.