my psychiatrist prescribed ENLYTE for depression.

Hi my daughters psychiatrist tried her on every med from A to Z and her reactions were all over the place. After years of trying so many medications from a young age this psychiatrist decided to do with DNA testing on her. It turned out that she has a double MTHFR gene mutations. If you look this up it tells you that people with the MTHFR gene mutation do not metabolize folic and b vitamins properly. Therefore leaving them depleted of what is essential for proper brain function. Having this gene mutation also causes people to not metabolize chemicals properly and this leads to your body not responding correctly to some medications. My daughter's dr. Gave her the Enlyte with delta folate and she did very well with it.

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Glad she has a good response to it... Ive seen a difference in depression with my son after starting him on it as well.... he still has anxiety issues but we are making progress where things seemed hopeless before

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Hello @gordonjackie722, I'm so pleased to hear that your son has shown an improvement with this new treatment. Is he back in school and doing OK with school work?

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Thank you for your kind reply... He is enrolled in an online HS program but daily doing work so I am happy with that.... just so thankful his depression isn't anything like it was

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I've been reading about EnLyte and it seems to be mostly a B12 combination. It stated that it is used as an adjunct to regular anti-depressants and it's primary use is for pernicious anemia. It states "Rx only" ..... so why is it on Amazon? I think I'll just push my intake of Vit B Complex, B-12 and B-16 up a bit and see if that does anything. If not, next time I see my Psychiatrist I'll ask him about it.
abby

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Hi. I am new to blogging. But I want to comment on the idea of buying B vitamins by themselves instead of the Enlyte:
It may not work. A family member has been prescribed Enlyte.
They did some tests on him and what I understand is that he lacks the enzyme that metabolizes folic acid and other B vitamins into the nutrient called l-methylfolate.
And so, just taking the vitamins would not work for him. He needs the l-methylfolate directly so that he won’t need to metabolize it in his body.
What I understand is that l-methylfolate is what really gets to your brain and helps it produce the seratonin and other substances that most people with depresión don’t produce easily in their brain.
So, it really may not help to just buy the vitamin B complex supplements.
Having said that I do have a question that you all may want to bring to your doctors:
There is l-methylfolate sold on Amazon by itself without the extra things that Enlyte has. It goes for ~$15 for 30 capsules of 7.5 mg which I similar to the 7mg that Enlyte claims to have
You may want to ask your doctors why that wouldn’t work.

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Enlyte is an UNAPPROVED drug for treatment of homocysteine metabolism problems and contains other vitamins, etc to treat anemia. It's allowed to be used by physicians because there are no comparable FDA APPROVED drugs. Glad it's helping some of you!

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I thanks for your reply.
What I am puzzled about is: If it is only the l-methylfolate that is not metabolized by the body of people in this condition, why buy a $52 bottle of Enlyte if I can buy a $15 bottle of plain l-methylfolate on Amazon. And in fact I can get a 90tablet bottle for about $25?

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Buy the n-methylfolate alone, but Google the manufacturer. You the absolute BEST manufacturer making your supplements, or they can be "sugar pills", since they are not regulated by FDA.

Signed: retired FDA scientist

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