Has anyone found a treatment that helps with peripheral neuropathy?

@cit10jetjockey
When I was 15 I cut my finger. I had no feeling from the scar to my fingertip, about 2" distance. I was told that nerves do not heal or regrow. When I was 23 i woke up one morning to insane tingling in that finger. The tingling lasted for months but then it all settled down. All my feeling in that finger had returned. Nerves can heal and can regrow.

@roncapstraw do you buy the R AMLA or the regular AMLA ? I was advised there could be a difference in effectiveness

@greengold No issues with blood sugar. Overall, I feel self-centered for complaining about PN, because I am incredibly healthy otherwise. My bloodwork and so on goes to the Cleveland Clinic and says I am doing great. My mother and father didn't have it and my sister (75) doesn't have it. Guess I am just the chosen one. 🙂

I'm 59. I am a diabetic since 2017 (A1C 8.7 - 10.7)and with major peripheral neuropathy which started with my toes (tingling, numb, etc..) in 2018. Until this day(2026), I have dealt with incurable, unmanageable, uncontrollable diabetes II and painful body peripheral neuropathy which has drastically grown and broaden from toes, feet, calves, thighs, waist to hands(fingers) which also brings sudden and sporatic extreme painful nerve lightning strikes.

After all the doctors, neurologist, specialist, emergency rooms, hospitals, prescribed medications such as (Pregabapentin/gabapentin, Juniva, Metformin, Duloxetine, 4 different injectable insulins, etc.. along with expensive massagers, creams, medical devices, and stuff such from Internet, Amazon and eBay to help with neuropathy at no avail which also and eventually brings major depression and weakness, abdomen pain, insomnia and not to mention, major anxiety.

As of today, I regret to spend thousands and thousands of dollars (Out of Pocket and/or Insurance) for diabetes, body neuropathy, along with the other medicatins for all their symptoms it brings to your mental and physical stages.

With disability claims denials, I am still forced to work to pay bills, and continue to live otherwise move to the streets. Not to mention, most employers seriously ignore and/or support your medical conditions even with ADA. I attempted to register for housing, funding, etc.. several times but it seems it is a waste of effort, time and energy.

Unfortunately and sadly, these serious mental and health complications and conditions were experienced as "NO CURE" ! The final solution mentioned by a honest emergency doctor was to amputate feet, and legs, and hands. There was some serious thought about it but ultimately refused the final solution.

After 8 years with such conditions and serious advise, you DO NOT want the neuropathy (PN-nerve damage) to grow, spread and affect your entire feet, calves, thighs, waist and hands as it is an extremely uneasy, painful, frustrating state of mind, serious anxiety, stress, etc. with daily activities... And not to mention, impotent for the last 7 years and specialized doctor(s) want 30K to make you believe that they can help with it. I declined!

From many years of experience, I found NO devices, creams, massagers, meds, specialist, doctors, etc. for PN and diabetes. Sadly, I have molded and learned to ignore ALL awful symptoms as it has been a part of my life for many years. And believe me, it is an extremely miserable way to live into the golden years and rest of your life......

As I feel daily discomfort and accepted "NO CURE", I purchased a 2 year dog (German Shepherd) to help encourage, motivate, smile, and walk at least 4 times a week which brings little help with body movements, muscles, and seldomly nerves regardless of the pain. He is amazing! I completely regret not doing so many years ago...as i still want to live a bit longer...or until I can no longer bare the body pain.

My advice is to eat healthy, daily walks, "exercise', remain optimistic and possibly adopt a dog for major encouragement, motivation, daily routine walk exercises, smiles, happiness, and most definitely "Save your Money" until maybe one day medical field will find a permanent solution for all experiencing these awful and serious mental and health conditions as I age. Ultimately, I am scared that all mental and physical symptoms will worsen before improving in my life time.

My prayers are with all of you …

A Man of No Cures!

@michhino

“I attempted to register for housing, funding, etc.. several times but it seems it is a waste of effort, time and energy.”

This is very true and no one knows how hard or impossible it is to get help until they have looked into it themselves. There really is no help as I have learned as I am going through this now. The only unhelpful advice for anyone I have is to not get seriously ill or pick up a condition while you are still of working age. If you are lucky enough that is. It is quite the rude awakening what you will find out dealing with medical professionals, social workers etc…..

@flaherty2185 here’s some research notes on the subject
Check out this answer from MediSearch! https://medisearch.io/share/3s13JtLVyUrVqosbW3VYMb

I have just discovered compression socks. Where have they been? I have severe PN in feet and calves. I’ve tried all the creams and the pain drugs. Nothing has kept the night electrical shocks away like compression socks. I wear the ankle length sock most the time. I put the, on first then my regular socks and shoes. I leave the compression socks on all night as well. They are working for me.

@graydude I was told compression socks shouldn't be worn at night. They have helped me greatly.

@dennyleo I’ve not heard that. In fact the opposite. I’ve been told the nerves do their best healing at night in any event. They work for me. Only thing I’ve found to offer relief

I was diagnosed after much testing to figure out what was going on and finally confirmed through punch biopsy in 2021. A reason not found yet, so I’m in the idiopathic group.
I was given gabapentin and worked up to 900mg 3X daily. I now take 300mg as needed, 1-3 times per day. I take a magnesium complex and I would recommend looking into the different types and applying the right ones to your needs. I just recently added ALA to my supplement regiment and haven’t taken long enough to know if that works or not. I was taking Cymbalta 60mg for depression and I chose the drug because it has an on label use for nerve pain. I took this for about 6 months and it really really helped but unfortunately my body was susceptible to some of the negative side effects and I discontinued. I would recommend giving a try. I ended up with dizziness that I could not control so I discontinued. I learned pretty quickly how to well it worked for the pain once I got off of it.
Movement, self care, diet, water and liquid IV are my go tos and seem to contribute significantly in the day to day.
Avoid extreme heat or cold - heat seems to be my enemy, especially humid heat.
Keep your hands and feet moisturized and socks on.
Footwear- comfortable footwear without the over abundant cloud cushioning. I found a pair of barefoot shoes that are amazing, I even used them for hiking in the Tetons and Yellowstone and they were amazing. I didn’t get the severe pins and needles that I would normally get from my regular Merrel and Keen hiking boots.
Stay away from processed foods. They ignite inflammation and trigger flare ups.