Reclast infusion long term side effects

@gently
That’s great information…now if I can get my doctor to follow it…I don’t yet know if reclast will be my follow up or Prolia…I’m 65 but good to know…you wouldn’t happen t9 have a link to that dr and statement?

@osteopatient2026 if you have a choice, do it in the abdominal area. You don’t want to waste a whole year (like I feel I did.). As far as the coronary calcification, I’m not sure where your information came from, but that’s absolutely incorrect. The calcium is well documented and studied to be damaging to arteries and add to heart disease, plaque deposits, and problems with kidneys. Talk to any doctor or do more research online. When the doctor assesses your cardiac health, they do a calcium test to assess the condition of your heart and arteries. It is a gold standard. You do not have to worry if you don’t have heart disease or coronary artery disease in your family history. You do not have to worry if you are not taking calcium supplements. Please do not take calcium supplements until you’ve had a blood test and you know your calcium levels.
Avoid the confusion by knowing which resources to use.
1) A TRUSTED doctor. Doctors can be wrong even the trusted one so always speak up if you’re intuition tells you to.
2) trusted resources like the NIH the national Institute of health. It is a great place to do research and see studies that have been peer reviewed for verification.
3) AI is great to get a bunch of information that’s integrated all at once, however, look where AI is getting their information. AI always lists it sources. AI is getting better and better all the time but it’s absolutely fallible so again take it with a grain of salt, but use it as a springboard.

I am 69 years old and it is really hard for me to remember/routine all the things I learn and investigate at this age. It helps to use this website and enlist the help of others to get information. Trust but verify is more than a political slogan.
I do a lot of research and go armed to my appointments. Some of my doctors can be difficult to work with. They don’t like their authority challenged. That’s too bad. I have found that in today’s medical climate doctors have less time for us. They don’t look beyond the symptoms and things that show up in a 20 minute visit. That means you may need to email them and after the visit and do more research and then follow up with them. Sometimes they they just don’t have the time and it’s incumbent upon ourselves to do the work unfortunately. Fortunately, there are groups like this where people will help!

@loriesco
Impact of Calcium Supplements on Coronary Calcium Score
Evidence of Risk:
Taking calcium supplements may be associated with an increased risk of arterial plaque buildup, which can lead to higher coronary calcium scores. This is particularly concerning as elevated scores indicate a greater risk of heart disease.
Dietary Calcium vs. Supplements
Dietary Calcium: Consuming calcium through food sources does not seem to carry the same risk as supplements. In fact, a calcium-rich diet may be beneficial for heart health.
Calcium Supplements: Research suggests that individuals who take calcium supplements may experience a rise in their coronary calcium scores over time. This is not observed in those who obtain calcium from their diet.
Summary of Findings
Risk of Elevated Coronary Calcium Score
Dietary Calcium Low risk; may be beneficial
Calcium Supplements Higher risk; linked to plaque buildup

In conclusion, while dietary calcium is generally safe and potentially beneficial, calcium supplements may pose risks that warrant caution. It is advisable to consult with a healthcare provider before starting any supplement regimen.
Johns Hopkins University
Harvard University

So depending on which school you went to there is conflicting studies …nonetheless id probably err on the side of caution…
My CAC score was 9 …crazy how one doc says no and another says maybe…they aren’t researchers either so I do the same thing…my own research …
One school of medicine says no another says maybe…😉
In addition….Stanford…
In most people, taking a calcium supplement does not directly cause a higher coronary artery calcium (CAC) score.
A CAC score measures calcium that has accumulated in plaque within the walls of the coronary arteries, not the amount of calcium circulating in your blood or the calcium you've recently consumed. The calcium in arterial plaque develops through a complex process related to atherosclerosis (hardening of the arteries), inflammation, and other biological changes over many years.
Here's what the evidence suggests:
Calcium supplements do not appear to increase CAC scores in a direct or immediate way. Taking a calcium tablet before a scan will not affect the result.
Large studies on whether long-term calcium supplementation increases cardiovascular risk have had mixed findings. However, many well-conducted studies and reviews have not found a clear increase in coronary artery calcification or heart attacks among people taking recommended doses of calcium supplements, especially when taken with meals.
Calcium from food sources (such as dairy products, leafy greens, and fortified foods) is generally not associated with increased cardiovascular risk and is often preferred when possible.
Factors that are much more strongly associated with a higher CAC score include:
Increasing age
High LDL ("bad") cholesterol
Smoking
Diabetes
High blood pressure
Family history of early heart disease
Chronic kidney disease
If you already have a high CAC score
A calcium supplement is not usually considered the cause. Instead, the score reflects existing calcified plaque that formed over time. Your healthcare provider may consider your overall risk profile to decide whether you should continue calcium supplements, especially if you're taking them solely for bone health.

@lynnsusan
Only if you can handle the risk of your jaw rotting out. Personally, I cannot. I'm done with all of these meds. I got a huge kidney stone on Tymlos. Doctor knows not to even mention the idea to me.

@lynnsusan
It depends on a lot of different factors but as it’s been stated here the last couple of years seems to be if you are in osteoporosis then starting with forteo, Tymlos Evenity followed by reclast, fosamax Prolia etc…many different variations for each patient …osteonecrosis happens rarely but again its patient dependent …if you hav3 healthy teeth and gums it’s less but still ther3 as a possibility nonetheless…ironically treated with Tymlos sometimes.
As many have said a fractured spine can be a whole lot worse than the alternative…it’s not an easy choice…

@osteopatient2026 I read that sometimes Evenity is given after 2years of Tymlos, that may be another option. OR.. short term oral Fosamax ( 1 year) hopefully wouldn’t cause teeth/jaw problems . After the 1 year of Fosamax hopefully another round of Tymlos. Your thoughts?

Yes…there is some thinking by some doctors (they all seem to have differing opinions) that it’s a reasonable approach. Again it depends on a patient and what their individual conditions are. TScore, kidneys other organs…previous cancer or existing conditions. Everyone is different…
On the osteonecrosis subject…generally that is caused by existing dental issues, poor hygiene, etc. A general dentist will or should refer a patient to a specialist (oral surgeon or at least someone experienced with osteonecrosis) before beginning a regimen of that class of drugs that do have a known history of Osteonecrosis…Tymlos is one drug used to treat it ironically. There is a special mouth wash used to keep your mouth clean as well.

Chlorhexidine gluconate rinse is commonly recommended for osteonecrosis of the jaw to reduce infection risk. Evidence for their effectiveness is based on expert opinion rather than definitive trials however.

Again if you are in severe osteoporosis your treatment will vary. Fosamax generally won’t help much if you are like me …my spine was -4.8- -5.1 hip was -3.1…the current approach was to try Tymlos or forteo (or Evenity which last year the doctor didn’t have enough experience with) now after a lot more people using it they seem to prescribing it more. There is better compliance with the once a month injection…so many variables…
I’m not a doctor although my husband went to med school and his brother and sister are. They can’t even agree on a lot of things!
I found some good info here… a few members have really scoured the info and found some indispensable info.

@osteopatient2026 I did what gently posted plus one extra day of 8 8oz cups of water, 650 mg Tylenol every 4 hours I think. Other than a bad headache (very short lived, on day 5) and maybe a little tired no problem. Asked doc for a slower drip; he told me to call infusion center. Infusion center said never heard of that. In and out in 30 minutes, start to finish, including time to make sure you don't have a reaction. I believe actual infusion was 15 minutes (that's what Novartis specifies on the drug literature). Just an FYI in case you do need to follow up with Reclast.

@gently I am not using bone markers. It's never been suggested. Also, I initially misspoke. It was Evenity I failed before Reclast and that caused similar bone pain, not Prolia. I'm going to ask my endo about bone markers. Thanks for the question.

hi carole,
most of our doctors aren't using bone markers. You might find the Doug Lucas video interesting https://www.youtube.com/watch I'm not shilling for him so I have to add don't buy anything.