Reclast infusion side effects?

@osteopatient2026 yes, at 65 I was given the shingles vaccine; 67 Reclast infusion! Nothing more from here on out to the end of my time. I am not nor will I be treated like a Ginny pig. I had felt pretty good prior outside of a lot of leg issues from Ankolosing spondylitis, which I have had since I was 18 years of age. Someone did a blood test and said, oh my, you need to see an endocrinologist because you might have the onset of osteoporosis, they say, you need a Reclast infusion…….i listened, you are the professionals, okay, wish I had said! “ NO”

@gently 69 year old male! I was given a steroid pack x 2 with no positive results! It’s been 26 months since I received my first and last infusion; never, ever again! It started with nausea, should pain and left foot! Nausea, shoulder pain, exhaustion, fatigue, vision blurry, lower back pain and latest is this constant shocking sensation whenever I cough in my groin and upper legs. Rheumatologist, neurologist and / or Endocrinologist all have no answer for the symptoms!

@osteopatient2026 Yes and timely. I read that they are looking into the possible high incidence of shingles after Prolia.

@karenjaninaz

Aha, yet another reason I won't go the Prolia route - my father had shingles and I am ter-ri-fied of getting them!

Thanks for the info!

Cheers!

@beanieone
“Prevention of Shingles”
The most effective method to prevent shingles is through vaccination rather than medication. The recombinant zoster vaccine, known as Shingrix, is the primary preventive measure.
Shingrix Vaccine
Effectiveness: Over 90% effective in preventing shingles and its complications.
Recommended Age: Adults aged 50 and older.
Dosage: Administered as a two-dose series.

@karenjaninaz

Aha, yet another reason I won't go the Prolia route - my father had shingles and I am ter-ri-fied of getting them!

Thanks for the info!

Cheers!

Hello,
I’m new to this forum.
I had a Reclast Infusion in May 2025. After a year dealing with knee pain issues my Dexa Scan results were terrible.
My endocrinologist had already suggested I’d need it, after doing some research I refused it for about 5 years.
Since the infusion, I’ve had digestive problems and pain on my left ribs. Strangely, on the first 24 hours after the infusion this is the exact place where I had intense sharp pain. It’s mostly during the night and in the morning.
Anyone experiencing the same?
Thank you!

@dannyandebbie
What blood test if you remember indicated you might have osteoporosis? Low urine calcium, or other?

danny, your experience makes it clear that the rheumatologist, endocrinologist and neurologist should be answering "Reclast."
I'm grateful that you reveal your experience. Otherwise no one will know the risk they are taking with this drug.
Ideally a person reacting to Reclast would have the steroid IV soon after the infusion (as some have been hospitalized), or better, prophylactically before the infusion. While I suspect that you may have received the steroid too late, I don't know if early steroid can resolve all the negative reaction to Reclast. That you are having new symptoms is a sign that maybe it doesn't. It doesn't even seem that any of your symptoms are lessening and this new symptom is appalling.
I do know that the reaction is seldom recognized as related to the infusion.
I've wondered, do you think that you were more at risk because of latent autoimmune systems? or is any suspected autoimmune reaction directly caused by the drug.
Thanks for continuing to post.

Hello,
I’m new to this forum.
I had a Reclast Infusion in May 2025. After a year dealing with knee pain issues my Dexa Scan results were terrible.
My endocrinologist had already suggested I’d need it, after doing some research I refused it for about 5 years.
Since the infusion, I’ve had digestive problems and pain on my left ribs. Strangely, on the first 24 hours after the infusion this is the exact place where I had intense sharp pain. It’s mostly during the night and in the morning.
Anyone experiencing the same?
Thank you!