Anyone with COPD taking Nucala (mepolizumab)? How did it help?

@hicopd Yep, I'm at 340. Can I ask what pharmacy you get yours mailed from?

Yes I use to get lung infection about every 6 weeks i have been getting those shots for 6 or 7 months and have not had lung infection since shots. Gil age 83

@hank82
Did it help with your everyday breathing.

Duplicate—see below

Mine is mailed from CVS Specialty Pharmacy. They even sent a nurse to instruct me and watch me give my 1st auto-injections shot. For me, my everyday breathing is pretty decent. I did notice that it boosted my resting O2 saturation rates. They were 92=93 and now they’re 94-95%. I don’t FEEL different but am happy. I do notice I don’t get an exacerbation when I have things that might normally trigger one, like if my POC malfunctions or I’m having a rough day due to other things.

@hicopd I noticed you said you blood was at 340, since you have been on it has your blood dropped to lower number?

My blood eosinophil levels were over 500. I'm not sure we've checked it since I started taking the biologics.

Im on dupixent, going now about my14/15 shot, I had a physical couple week ago and they did a cbc my eso were 0, deer said it was because I have been taking the dupixent. Make since, I would like to make sure i’m not taking anything i dont need.

@hicopd were you on oxygen before you started taking the Nucala? I was on it 24/7 but after my first shot I found that I could sit without using the oxygen. And since my second shot I am starting to be able to move around "slowly" and in "short spirts" without the oxygen. Hoping that I will eventually be able to get off the oxygen all together.

I've been on supplemental O2 since 2008 for altitude. In 2016, they also told me I need it for sleep and exertion. I am guided by my pulse oximeters. I am OK without O2 for just sitting with room air (it used to be 92-93 and now can be 94-96% sitting). If I walk slowly (like around my house), I generally am OK without O2 as well. If I'm going to walk and don't want to do pursed lip breathing continuously and watch my oximeter, I just wear my O2, so I don't stress my heart. It's just easier and better for my heart. I really don't want to develop heart problems in addition to my bad lungs.

I have an Inogen Rove6 and just bought a waistpack that has a crossbody strap. It works very well for me and allows me to be hands-free while wearing it. I am getting used to not getting tangled up with the tubing (always a work in progress). I prefer it over the single shoulder strap and over the backpack because I can turn the O2 on or off and also adjust settings as needed.

The last time I had a 6 minute walk test (while being on biologics), I needed to crank my POC up to level 6 (the max) to keep my pulse from being at an unsafe rate, as well as to keep my saturations up. I prefer walking at a fairly brisk pace, so that may be part of the issue.

Of course, it was nice before I needed supplemental O2, but I don't see myself being able to get rid of it at this point. I prefer to protect my brain cells and heart, so they need O2 and I will be sure they get it. I really dislike having my heart race when my O2 saturation levels drop.