Has anyone found a treatment that helps with peripheral neuropathy?

Posted by bigjohnscho @bigjohnscho, Jul 1, 2025

I suspect that everyone on this forum has been searching for a medication that helps their neuropathy and even though you no that all the internet claims are false we continue to waste hundreds of pounds. Desperation is a powerful force. Has any one been fortunate enough to find a genuine treatment. I just can’t believe that there are so many awful people who prey on our vulnerability and knowingly orchestrate such elaborate scams.

Interested in more discussions like this? Go to the Neuropathy Support Group.

I find that daily use of 5% lidocaine on my feet and a consistent program of working out eases the pain somewhat.

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Profile picture for ronvt @ronvt

@heisenberg34 In my experience, any other pain issues I have (bursitis, arthritis, etc.) are amplified by neuropathy. If those issues can be identified, steroid shots or other localized pain management techniques can be very helpful. My wife has severe lower back pain, and she gets a nerve ablation every six months, which helps a lot. As far as exercise goes, walking a mile or two every day I can works best for me, as I also have exercise resistance and dysautonomia that kick in if I get my heart rate up too much (100+ bpm). If you can't reduce your pain enough while walking to be tolerable, swimming is probably your best option if you have access to a pool. It takes the weight load off your lower back and legs. I have even seen people walking in a pool.

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@ronvt Thanks for your response. We do have a pool in our development. I'm not sure that I'm brave enough to show up in my swim suit. I don't want any of the ladies to swoon at the sight of my rippling physique. LOL.

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Profile picture for heisenberg34 @heisenberg34

@ronvt Thanks for your response. We do have a pool in our development. I'm not sure that I'm brave enough to show up in my swim suit. I don't want any of the ladies to swoon at the sight of my rippling physique. LOL.

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@heisenberg34 There is comfort in numbers. Find some partners in crime to swim with you.

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Profile picture for heisenberg34 @heisenberg34

@ronvt Thanks for your response. We do have a pool in our development. I'm not sure that I'm brave enough to show up in my swim suit. I don't want any of the ladies to swoon at the sight of my rippling physique. LOL.

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@heisenberg34 Yesterday I finally was able to take a walk outdoors because I am in the mountains for a few weeks and away from my primary home which presently has the third most hazardous air quality in the world because of major fires smoke drifting down over the majority of our state (Minnesota). The walk was short but then I visited our pool and heated hot tub with jets. I allowed the jets to blast my legs from the knees on down to the bottom of my feet. I couldn't stay in too long because the heat really was very painful after a while (IPN bothers me primarily on my ankles and feet). I then went into the pool which cooled off my legs. I did 15 minutes of legs exercises - I was in at 3 ft. deep - from squats to single leg stretching. THE PAYOFF - I had a great nights sleep and, my legs/feet were pain free!!
The morale of this long drawn out story is that for some of us, not all (for numerous reasons) exercise and mobility on a daily basis can do wonders!

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Profile picture for mikead63 @mikead63

@heisenberg34 Yesterday I finally was able to take a walk outdoors because I am in the mountains for a few weeks and away from my primary home which presently has the third most hazardous air quality in the world because of major fires smoke drifting down over the majority of our state (Minnesota). The walk was short but then I visited our pool and heated hot tub with jets. I allowed the jets to blast my legs from the knees on down to the bottom of my feet. I couldn't stay in too long because the heat really was very painful after a while (IPN bothers me primarily on my ankles and feet). I then went into the pool which cooled off my legs. I did 15 minutes of legs exercises - I was in at 3 ft. deep - from squats to single leg stretching. THE PAYOFF - I had a great nights sleep and, my legs/feet were pain free!!
The morale of this long drawn out story is that for some of us, not all (for numerous reasons) exercise and mobility on a daily basis can do wonders!

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@mikead63 Good for you! I may go down to our community pool before the season ends. Not sure if I want to expose my amazing body to the older gals. LOL

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I have found a treatment that works for me. It is a kind of physical therapy called the McKinsey method. I believe the particular move that made me realize it actually worked was called neural threading. I can breathe and sleep better. Maybe that is part of the relief I feel. Unfortunately, my therapist was part of a business model with policies that focus on profit rather than healing, so I am no longer with her, but will find another practitioner.

If you try to find this, be sure the person is fully certified to do the McKinsey method. I wasted time on therapists who were kind of half qualified. Also imo you need a therapist who is physically bigger than you are. She or he needs to be able to move your limbs in ways that involve rather large spaces.

I doubt very much that the therapists or people who teach the method claim that it cures PN. I am just saying it works for me. Maybe my problem is not the same as yours. Who knows?

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Haven't found anything that really helps...in fact somethings that are suppose to help actually feel like it makes it worse... Like ALA....Nitric Oxide...
Little scared of Vitamin B12 because we are told too much can cause your neuropathy to be worse??
What I know... I don't remember having this before Covid... So I think mine is Covid related, This year..yea it took this long for me to figure out...Heat makes it worse, like a hot tub, shoes that are ventilated well...or soft enough
luckily my job isn't on my feet all day...I can sit for minutes and let my feet calm down before I have to go again...
If I had a job that kept me on my feet all day...I would have to retire or change jobs, and at 69years old I prefer to stay here and retire from this one...
There are good days....good nights and there are bad.. If its a bad night, my feet up to my knees will hurt and I found if I put my feet out of the cover into the cool air of the room it helps...
I've tried peptides...probably didn't give them a fair chance... might try again ARA290....if you would like to research it...
I guess I'll try Vitamin B12 METHYLCOBALAMIN.... I'll try anything at this time..

Good Shoes help...... NB 1080 are like walking on mashmellows..... Hokas Cliftons... I also like Skeckers Slip on's MAX Comfort but you need to try them because the comfort isn't always the same with Skeckers

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