Buspirone and side effects

Posted by hrod @hrod, Dec 3, 2022

I started taking 5 mg buspirone twice daily for significant anxiety due to chronic pain but the side effects are overwhelming with nausea, drowsiness, leg weakness, etc. Anyone have experience with this medication and whether the side effects go away? Has it been effective for you? Doctors seem to think this is a safe medication and good for older people, but they don't tell you to expect these side effects. Your input and experience with this drug is greatly appreciated! Thanks

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Profile picture for beesmom @beesmom

Yesterday I was prescribed Buspirone to take in addition to my daily dose of 100mg of Zoloft. Is anyone else on these same meds, and have you had success or negative reactions? Thanks!!!

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I just recently increased my dosage of Buspirone. I do have occasional
audio noises that aren't there just when starting to wake up--anyone else?

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Profile picture for djg3012 @djg3012

I just recently increased my dosage of Buspirone. I do have occasional
audio noises that aren't there just when starting to wake up--anyone else?

Jump to this post

Hi, @djg3012 - You may notice that I moved your post and combined it with this existing discussion on buspirone, because I thought it might be beneficial for you to be introduced to members who have discussed the same over many years:

- Buspirone: Anyone on this? How's it gone? https://connect.mayoclinic.org/discussion/buspirone-1/

If you are replying by email, click on VIEW & REPLY so that you can read through some of the earlier messages and meet some of the other members talking about their or their or their loved ones' experiences.

Fellow members such as @bren10 @worriedgal1 @dilly22 may have some input for you on buspirone and if they have experienced side effects, including audio noises that are not there when just starting to wake up. @gingerw also may have some thoughts to share.

While awaiting their replies, you might check out this Mayo Clinic article on this medication, which includes side effects:

- Buspirone (oral route) https://www.mayoclinic.org/drugs-supplements/buspirone-oral-route/description/drg-20062457

djg3012 - what did the physician who prescribed the buspirone say about the audio side effect you mentioned?

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Profile picture for Lisa Lucier, Moderator @lisalucier

Hi, @djg3012 - You may notice that I moved your post and combined it with this existing discussion on buspirone, because I thought it might be beneficial for you to be introduced to members who have discussed the same over many years:

- Buspirone: Anyone on this? How's it gone? https://connect.mayoclinic.org/discussion/buspirone-1/

If you are replying by email, click on VIEW & REPLY so that you can read through some of the earlier messages and meet some of the other members talking about their or their or their loved ones' experiences.

Fellow members such as @bren10 @worriedgal1 @dilly22 may have some input for you on buspirone and if they have experienced side effects, including audio noises that are not there when just starting to wake up. @gingerw also may have some thoughts to share.

While awaiting their replies, you might check out this Mayo Clinic article on this medication, which includes side effects:

- Buspirone (oral route) https://www.mayoclinic.org/drugs-supplements/buspirone-oral-route/description/drg-20062457

djg3012 - what did the physician who prescribed the buspirone say about the audio side effect you mentioned?

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@lisalucier I haven't mentioned that-thought it was the anxiety, as I am still on 15 mg. it doesn't happen every day.Am still experimenting with dosage.

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Profile picture for beesmom @beesmom

Yesterday I was prescribed Buspirone to take in addition to my daily dose of 100mg of Zoloft. Is anyone else on these same meds, and have you had success or negative reactions? Thanks!!!

Jump to this post

I recently went from 20mg to 30mg of buspirone after 2 years. I couldn’t tell much difference. It is a very mild drug in my experience.

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Profile picture for beesmom @beesmom

Yesterday I was prescribed Buspirone to take in addition to my daily dose of 100mg of Zoloft. Is anyone else on these same meds, and have you had success or negative reactions? Thanks!!!

Jump to this post

I have been on Buspirone for seven years now. Prior to Buspirone, I was on Klonopin and I was concerned about becoming too dependent on it. Buspirone is a much safer medication and for me, and it is just as effective. I do sometimes hear a buzzing sound in my ear right after I take the medication. I call it the "Buspar Buzz." Per my doctor's suggestion, I find that if I take only 7.5 mg of Buspirone at a time, the buzzing sound disappears. As a result, I break the 15mg tablet in half for each dose. I take 7.5 mg in the morning, 7.5 mg at noon and 7.5 mg in the evening. I can tolerate the medication much better. When I first started taking it, I felt a little dizzy; however, these side effects wore off after I was on the medication for a couple of months.

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Profile picture for joetex @joetex

I recently went from 20mg to 30mg of buspirone after 2 years. I couldn’t tell much difference. It is a very mild drug in my experience.

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@joetex I agree that it seems like a very mild drug. I am not sure if it really does anything. I take Rexulti, Busparone and Zoloft 200 mg. I don’t have any anxiety now.

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Profile picture for beesmom @beesmom

Yesterday I was prescribed Buspirone to take in addition to my daily dose of 100mg of Zoloft. Is anyone else on these same meds, and have you had success or negative reactions? Thanks!!!

Jump to this post

I take Zoloft 200 mg and Buspar, 5 mg, but also Rexulti.

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Profile picture for seeker4truth @seeker4truth

I have been on Buspirone for seven years now. Prior to Buspirone, I was on Klonopin and I was concerned about becoming too dependent on it. Buspirone is a much safer medication and for me, and it is just as effective. I do sometimes hear a buzzing sound in my ear right after I take the medication. I call it the "Buspar Buzz." Per my doctor's suggestion, I find that if I take only 7.5 mg of Buspirone at a time, the buzzing sound disappears. As a result, I break the 15mg tablet in half for each dose. I take 7.5 mg in the morning, 7.5 mg at noon and 7.5 mg in the evening. I can tolerate the medication much better. When I first started taking it, I felt a little dizzy; however, these side effects wore off after I was on the medication for a couple of months.

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@seeker4truth does it affect your sleep ?

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Profile picture for kellen @kellen

@joetex I agree that it seems like a very mild drug. I am not sure if it really does anything. I take Rexulti, Busparone and Zoloft 200 mg. I don’t have any anxiety now.

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@kellen wow. are they all for anxiety? do you take any sleep meds?

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Profile picture for kellen @kellen

@joetex I agree that it seems like a very mild drug. I am not sure if it really does anything. I take Rexulti, Busparone and Zoloft 200 mg. I don’t have any anxiety now.

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@kellen are any of these habit forming

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