Has anyone found a treatment that helps with peripheral neuropathy?

Posted by bigjohnscho @bigjohnscho, Jul 1, 2025

I suspect that everyone on this forum has been searching for a medication that helps their neuropathy and even though you no that all the internet claims are false we continue to waste hundreds of pounds. Desperation is a powerful force. Has any one been fortunate enough to find a genuine treatment. I just can’t believe that there are so many awful people who prey on our vulnerability and knowingly orchestrate such elaborate scams.

Interested in more discussions like this? Go to the Neuropathy Support Group.

Profile picture for jamessaxo @jamessaxo

Neuropathy is nerve pain caused by their missing insulation. Vitamin C grows new nerves but only vitamin B12 insulates them. Just like electric wires. Take PLENTY of B12 . Best form is METHYLCOBALAMIN. Best food sources are liver and mussels. The very foods most people never eat.

Jump to this post

Interesting. I've been told I have small fibre neuropathy. I've been through all the hoops, consulted neurologists and others.
I did read, on Facebook of all places, an article about vitamin b12 deficiency. In the UK a blood test is done checking possible culprits for your symptoms. Mine was, mainly, an ice cold sole of left foot but both affected; sometimes burning, always tingling.Maddening. Relief when in bed at night. This article said that the standard NHS test for b12 is flawed, as it measures total b12. There is active and non active b12. Only active should be measured. To cut a long story short I challenged my GP, no joy. So, eventually I oaid for a private test on active b12. It was 30% below the lowest on normal range. My GP checked this then put me on 6 loading doses of b12 over 2 weeks. I've had to continue pushing but,with neurological issues, the Nice ( NHS overseeing body), guidelines state that the injections should then continue every other day until no further improvement. That's where I am. It's early days but I'm hopeful.
I've been tested for pernicious anaemia but it was negative. However it seems that test doesn't pick up all cases so I'm thinking about next stepson this. PA is main cause of b12 deficiency. Not the only one though. Proton Pump Inhibitors taken long term are a cause too( that's used for acid reflux). And others.
I'll update in a few weeks..

REPLY
Profile picture for jamessaxo @jamessaxo

Neuropathy is nerve pain caused by their missing insulation. Vitamin C grows new nerves but only vitamin B12 insulates them. Just like electric wires. Take PLENTY of B12 . Best form is METHYLCOBALAMIN. Best food sources are liver and mussels. The very foods most people never eat.

Jump to this post

Prior to 1932 liver was the only treatment available for pernicious anaemia. Mow it's regular injections of b12.

REPLY
Profile picture for geet69 @geet69

@johnbishop
what brand of Na-R-AlA do you use?

Jump to this post

@geet69 In the past I've used Doctor's Best and Geronova brands but now it's included in the supplements I take - https://theprotocolworks.com/the-science-behind/.

REPLY

I had an afternoon to spare so I reread notes on peripheral neuropathy treatments. I was shocked to find how little progress has been made. It’s the same old formulas still being churned out. I cannot believe we’re still being conned into spending 100’s of pounds on products we know doesn’t work.There must be thousands of super clever people reading this stuff and they know it’s absolutely garbage. Unfortunately I’m not clever enough to to work out the answers but I’d like to think I’d help my friends making the same mistakes over and over again. Come on lads we might beat this if we all helped.

REPLY
Profile picture for jamessaxo @jamessaxo

@granny73 At last. Someone has found out about vitamin B12.

Jump to this post

Vitamin b12 deficiency is a cause of peripheral neuropathy. I'm assuming it's been discussed on here in the past? See my earlier post on this.

REPLY
Profile picture for bigjohnscho @bigjohnscho

I had an afternoon to spare so I reread notes on peripheral neuropathy treatments. I was shocked to find how little progress has been made. It’s the same old formulas still being churned out. I cannot believe we’re still being conned into spending 100’s of pounds on products we know doesn’t work.There must be thousands of super clever people reading this stuff and they know it’s absolutely garbage. Unfortunately I’m not clever enough to to work out the answers but I’d like to think I’d help my friends making the same mistakes over and over again. Come on lads we might beat this if we all helped.

Jump to this post

@bigjohnscho

This is what I was getting at in my post that this disease needs more advocacy. Its the same old treatments from the 90s - gabapentin and lyrica.

Well I guess there was one company with real scientists and research behind their drug - Winsantor but looks like no one had interest which I don’t get. I believe there was also a Korean company working on a drug at one point but that also folded.

REPLY
Profile picture for John, Volunteer Mentor @johnbishop

@geet69 In the past I've used Doctor's Best and Geronova brands but now it's included in the supplements I take - https://theprotocolworks.com/the-science-behind/.

Jump to this post

@johnbishop
Has it helped?

REPLY
Profile picture for chandria40 @chandria40

@chandria40 I feel like it has slowed the progression a little but haven’t had any additional testing to prove it.

REPLY
Profile picture for John, Volunteer Mentor @johnbishop

@chandria40 I feel like it has slowed the progression a little but haven’t had any additional testing to prove it.

Jump to this post

@johnbishop

Okay, how are you feeling. Has it impacted your day to day activities. More strength or capacity to do "normal " activities?

REPLY
Profile picture for chandria40 @chandria40

@johnbishop

Okay, how are you feeling. Has it impacted your day to day activities. More strength or capacity to do "normal " activities?

Jump to this post

@chandria40
Is this a B12 supplement?

REPLY
Please sign in or register to post a reply.