ADT and rising PSA

Posted by mjp0512 @mjp0512, May 20 8:27pm

I could have added this to my previous discussions of “PSA Wrong Direction” but felt this is important enough for its own thread.

A couple of things I’ve learned since I started that first discussion in December:

1. If you are on ADT, your PSA is NOT SUPPOSED TO RISE!

If your PSA starts going in the wrong direction, even if it is a minimal increase, as mine was, DO NOT listen to the conventional wisdom of…

“It’s probably just a “minor bounce” or “lab variance” or “inflammation from radiation”. We’ll check it again in a few months”.

If you are on ADT, your PSA is NOT SUPPOSED TO RISE!

INSIST on monthly PSA testing immediately. Had I done so last December, the flare up on my spine would have been caught sooner, treated sooner, and I might still be able to walk normally and sleep through the night. Instead, it’s six months later and I don’t even start treatment until next week. It’s a $60 test. DEMAND it. If it turns out to be nothing, no harm, no foul. But if you can catch something earlier, maybe it can be treated before it hurts.
PSA:
4/21/25 - 30.11
6/7/25 - start ADT
7/9/25 - 0.55
8/26/25 - 0.19
10/2025 - IMRT
12/3/25 - 0.23
3/17/26 - 8.80
4/1/26 - 10.29
5/18/26 – 14.90

And…

2. Prostatic Adenocarcinoma is a very slow growing cancer…until it isn’t.

That is all…Don’t make my mistake.
Enjoy your day!

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Profile picture for surftohealth88 @surftohealth88

@mjp0512

Yeayyyy !!! : )))

I am so happy to hear that pain is truly and completely gone 👍😊 - one victory at the time : ))) !
There is a great chance for that PSA is way down too 🍀 now that lesion is removed : ))) .

Ha ha for kitty - is it male or a female, what is his/her name ? : ) It must be really nice cat when she is good around your tiny quails and gives you no trouble there. ; )

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@surftohealth88 - Her name is Kat and she's not allowed in the quail shed. She gets nuts when a bird lands on the deck. Couldn't imagine the carnage if she was in a room full of birds.

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Profile picture for mjp0512 @mjp0512

@surftohealth88 - Her name is Kat and she's not allowed in the quail shed. She gets nuts when a bird lands on the deck. Couldn't imagine the carnage if she was in a room full of birds.

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@mjp0512
Ha ha, oh boy, she has good hunting instinct as most kitties do, not much help there lol. I have many bird feeders and constantly have to be on a lookout for stray cats 😬. My neighbors probably have a good laugh seeing me chasing them around with water hose lol I LOVE cats, just not under my bird feeder ha ha. They come handy actually hunting for all kind of vermin around property, so I do not chase them very far away 😜.

Cute name, BTW 😺 <3 !!!

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Profile picture for mjp0512 @mjp0512

@surftohealth88 - Hi surf...thanks for checking in. Yep, still pain free and sleeping great (until the cat decides it's time to get up) Met with oncologist on 6/2, pretty simple plan going forward. Blood tests on 7/2, if PSA is falling, all good and continue to monitor. If PSA is still rising, off to chemo I go. Wants to put me on Denosumab (Xgeva) too but I'm pretty sure my dentist is going to veto that when I see him Friday. Been dealing with jawbone issues since way before all this cancer nonsense started.

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@mjp0512 Xgeva definitely a problem in the jaw. Consider Fortibone - collagen peptides which are the actual ‘scaffolding’ for bone growth.
You take one scoop per day and along with good Calcium, magnesium and Vit D3 supplements you will maintain and build new bone.
My wife has been on it for one year and is looking forward to her next bone density test. She is also a dentist and flatly refused any of the meds they trued to put her on. Best,
Phil

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Profile picture for heavyphil @heavyphil

@mjp0512 Xgeva definitely a problem in the jaw. Consider Fortibone - collagen peptides which are the actual ‘scaffolding’ for bone growth.
You take one scoop per day and along with good Calcium, magnesium and Vit D3 supplements you will maintain and build new bone.
My wife has been on it for one year and is looking forward to her next bone density test. She is also a dentist and flatly refused any of the meds they trued to put her on. Best,
Phil

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@heavyphil - Hi ya Phil... Thanks!! (and please extend that to your wife) I'm about 90% there to tell them to keep the Xgeva but since my GUO is highly regarded in his studies of bone mets, I need to give his opinion thorough consideration. To that end, my final decision will be after my dentist, who's expertise happens to be dental bone reconstruction, renders his opinion this Friday.

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Profile picture for surftohealth88 @surftohealth88

@mjp0512
Ha ha, oh boy, she has good hunting instinct as most kitties do, not much help there lol. I have many bird feeders and constantly have to be on a lookout for stray cats 😬. My neighbors probably have a good laugh seeing me chasing them around with water hose lol I LOVE cats, just not under my bird feeder ha ha. They come handy actually hunting for all kind of vermin around property, so I do not chase them very far away 😜.

Cute name, BTW 😺 <3 !!!

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@surftohealth88 - I live in farm country so feral barn cats are prolific here. Great at keeping rodent populations under control but I stopped putting out bird feeders years ago. No sense in setting up a buffet for them.

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Profile picture for mjp0512 @mjp0512

@surftohealth88 - I live in farm country so feral barn cats are prolific here. Great at keeping rodent populations under control but I stopped putting out bird feeders years ago. No sense in setting up a buffet for them.

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@mjp0512 Funny you post this! Saw a Youtube video about this just last night: even a cat who just finished a huge meal can’t help him/herself from attacking the birds at a feeder. It’s just what the cat is hard wired to do…good move in not putting up feeders!
Phil

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Profile picture for mjp0512 @mjp0512

@heavyphil - Hi ya Phil... Thanks!! (and please extend that to your wife) I'm about 90% there to tell them to keep the Xgeva but since my GUO is highly regarded in his studies of bone mets, I need to give his opinion thorough consideration. To that end, my final decision will be after my dentist, who's expertise happens to be dental bone reconstruction, renders his opinion this Friday.

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@mjp0512
If you’re not having any problems with Xgeva Then continuing it makes sense. It’s only for two years. One of the people I know who is sort of an expert in this says that once that two years are up, you should take Zometa for one time, and it will lock in all the benefits Xgeva Provides.

Zometa has a much lower chance of causing osteonecrosis. You could ask your doctor about using it instead. My oncologist had me use it because of that reason. You could also use Fosamax Which has a much lower chance of problems, It’s a pill you take once a week.

I was on Fosamax For six years and then had Zometa for two years. My DEXA seems good and I’ve had no jaw bone problems.

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Profile picture for Jeff Marchi @jeffmarc

@mjp0512
If you’re not having any problems with Xgeva Then continuing it makes sense. It’s only for two years. One of the people I know who is sort of an expert in this says that once that two years are up, you should take Zometa for one time, and it will lock in all the benefits Xgeva Provides.

Zometa has a much lower chance of causing osteonecrosis. You could ask your doctor about using it instead. My oncologist had me use it because of that reason. You could also use Fosamax Which has a much lower chance of problems, It’s a pill you take once a week.

I was on Fosamax For six years and then had Zometa for two years. My DEXA seems good and I’ve had no jaw bone problems.

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@jeffmarc - My problem, Jeff is that I have had jawbone issues for as long as I can remember. This includes 2 bone grafts that were only partially successful. I consistently deal with loose teeth resulting from pocket deterioration. Not a poor home care thing, my jaw is just built that way. That's why I'm so leery of any meds where ONJ is a possible side effect. I haven't started the drug yet and I'm pretty sure my dentist is going to veto doing so. We'll see on Friday.

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Profile picture for mjp0512 @mjp0512

@surftohealth88 - I live in farm country so feral barn cats are prolific here. Great at keeping rodent populations under control but I stopped putting out bird feeders years ago. No sense in setting up a buffet for them.

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@mjp0512
Heh, so far just few casualties in 10 years here. Maybe 3 or 4 since I have motion activated sprayers too and outside multiple rig cameras and feeders placed out of the cats easy reach. They all were caught actually while drinking water , not while on the feeder or around it : ((

To be honest the most damage is done by pray birds, BUT my tiny song friends are very smart and know when to hide in nearby bushes. Since I started feeding birds the population of songbirds in our street grew exponentially ! There were virtually none when we came since we live in the middle of a huge city. I consider it "natural selection" because size of population is growing too fast. An occasional casualty is just deemed to happen, this or that way. In big cities big glass buildings do more damage than any other predator due to constant collision accidents : (, thousands of birds die.

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