GLP-1 Drugs Causing Arrythmias

Did they stop ?

@swex
There is a study that shows it is helpful for many afib patients who are overweight and also lowers repeat episodes of afib for most of the 2500 people in the study. But it can do what happened to you. They need further studies. There are other types of weight loss drugs but I don’t know yet if glp1 is a single drug or a heading for different kinds of drugs. This study is at hrsonline (heart rhythm society online) dot org/ glp1-study-reduces-afib-events

I coincidentally had a 48h holter on at the same time I was on GLP-1s.

Didn't even have a skipped or delayed beat. All good in their eyes.

Was there any evidence these meds cause tachycardia? I have been taking GLP1s since August of last year. In recent months my tachycardia has increased as part of autonomic storms. I need to lose weight for apnea, my metabolic health and joint problems with EDS, but not if this med is in any way responsible for my autonomic symptoms. Do you know where to find the study?

I have been on Zepbound for over a year for sleep apnea and lost 27% of my weight. I experienced a-fib for only a couple minutes when I first started Zepbound but have had no issues since. I think this was because my weight loss was so rapid and because I was not eating much food and also not getting enough protein. Once my body got accustomed to the GLP-1 I have had no issues and feel great. In addition to my sleep apnea getting better I am no longer pre-diabetic. I only went up to 10 mg and had already lost 47 pounds in 8 months so I gradually decreased to 7.5 mg and am now on 5 mg every 7-10 days as maintenance. I have not put on any weight even though I am eating more than I did at the higher doses.

@swex This is me too although not persistent. Once i went up to 1.7 it started happening once every few weeks. My ablation was 4 years ago. My cardiologist also didn’t seem to be sure of the connection although dehydration used to be a trigger for me. I dropped back to 1mg this week but now also have to have another ablation which is gutting. There simply isn’t enough research on this to be sure.

@monty64 There is roughly a 50% chance that any one patient with a successful ablation lasting over four years will soon require another ablation due to recurrence of AF. The rate of recurrence 6 years out is about 30%. So, if you make it to the 5-6 year mark, the chances are you'll never require another ablation. For many of us, we don't make it past about 3-4 years, so......yer in good company. 😀 Still, I'm sorry this has been the case for you. I can't say it wasn't a GLP-1, but the odds of getting past 4 years anyway, regardless of other factors, is not very high for ablatees.

I have paroxysmal afib and flutter and have been on Foundayo for 4 months. No apparent increase.

I was on Wegovy for approx four months and my usual resting heart rate was 60 bpm. All of a sudden it sped up to 98 beats per minute while resting and continued. Went to the ER where they did numerous tests. Came up with no results. Except that it started while I was on Wegovy. Stopped it. Went to my cardiologist and he suggested to try it again in a month. After one injection, same thing happened. Rapid heart rate. I stopped again. Does anyone know of a weight loss drug that doesn’t affect heart rates???

Ezetimibe. Maybe. You could ask for a trial.