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Why do medications meant to lower my BP raise it instead?

Posted by acblack629 @acblack629, Jan 28, 2024

I'm 42 and have very odd side effects to not just bp medicine. However I went to my cardiologist for occasional pvc and occasional high bp. I'm far worse now than I was when I started It's common for me to try a new medicine while hooked up to monitors & the BP medicine to immediately put me in bi or trigemeny rhythm, weaken my pulse or run my heart rate up high, and raise my BP instead of lowering it. I'm currently on a heart monitor and am trying clonidine patches. I started at 143/83 put on the patch it's steadily gone up to 208/138 so far . Anyone have an idea why? My cardiologist just keeps throwing pills at me and only believes me when he sees the monitor ( this has happened plenty of verifiable times in medical facilities). Labetilol, cardene, hydralazine, etc Even pills like losartan & lisinopril give me side effects like nose bleeds, chest pain, not being able to breathe, and not lowering my BP. Any thoughts or tests I could suggest would be helpful. Thanks

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Mentor
Janell, Volunteer Mentor | @jlharsh | May 13 7:01pm

Hi @acblack629. I am wondering how you are doing. What have you learned since creating this discussion about blood pressure medications increasing your pressure instead of controlling it.

Have you learned more about your blood pressure? How are you feeling?

REPLY
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leze | @leze | May 13 8:27pm
In reply to @jlharsh "Hi @leze, and welcome to Mayo Clinic Connect. Your resistant blood pressure is caused by something,..." + (show)
Profile picture for Janell, Volunteer Mentor @jlharsh

Hi @leze, and welcome to Mayo Clinic Connect. Your resistant blood pressure is caused by something, please do not give up!

I notice @swade88 commented and may have more to share.

You are headed for serious problems the longer your blood pressure is not controlled. Blood pressure is determined by two things: the amount of blood the heart pumps and how hard it is for the blood to move through the arteries. Here is some general information from Mayo Clinic if you haven’t had a chance to review it:

- Mayo Clinic High Blood Pressure (Hypertension) Overview:
https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/symptoms-causes/syc-20373410
I also found an article that may guide you through troubleshooting you can do yourself. I’m not familiar with the source so please don’t use this as a substitute for medical advice.

-Resistant Hypertension: When BP Stays High Despite Medication
https://expressinternalmed.com/blog/uncontrolled-hypertension-causes/
I have had amazing success at Mayo Clinic MN and highly recommend their integrative care. You can pursue an appointment here: http://mayocl.in/1mtmR63

What guidance for follow-up do you get from the ER, especially after several visits? What have you learned about what is and what is not causing your hypertension?

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@jlharsh
Thank you so much for replying.
I have been to Mayo Rochester on 2 separate occasions last year. My abnormal blood test results suggested a secondary cause and I was told a scan would reveal either a tumor or growth of the adrenal glands (it was suggested that it was probably primary aldosterone). The scan revealed nothing untoward. It has left me with no path forward. In other words, no tests are revealing any reason for the very high pressure and I am very concerned but don't know what to do.
Thank you again.

REPLY
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lolalulu | @lolalulu | Jun 2 9:20am

I am going through the exact thing. I have high BP and Hashimotos. After Covid I have been to the er 4 times for tremendous spikes to my BP. This has happened with four different meds. I take a moderate dose and it works well until it stops working so Drs. Increase dose and my BP starts spiking and dropping with huge bumps in hr to 140. This goes on for days. Bloodwork looks great

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