Success with low dose naltrexone for Autoimmune disorders

Posted by julie868 @julie868, Feb 13, 2020

Low Dose Naltrexone, otherwise known as LDN, seems to be helping a lot of people lately who have all different types of autoimmune disorders.
The information I read sounds very interesting and would like to know if anyone has tried it personally?

The theory that I read says that many autoimmune issues are caused by a deficiency in endorphins, endorphins regulate the immune system. LDN temporarily blocks the body's natural endorphin production for a few hours, this tricks the body into thinking it needs to increase endorphin production. When the blockade wears off, all the endorphins are released into the body, regulating the immune system and providing natural pain relief for the rest of the day. Apparently, LDN can increase your endorphins by up to 300%

LDNscience.org has a lot of information and research about it. You can also look at the writer, Annie Habler (@hablerannie) on Medium.com who wrote an article recently about the fascinating background and history of LDN.

Please let me know if you have tried it and what your experience was like. If you could let me know any details your condition,the dosage you used, any side effects, etc it would be helpful.

Thank you!

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aspyres | @aspyres | May 8 7:31am

I missed a dose of LDN, and had a flare in severity of vasculitis rash, and bone pain. I did get started back on it immediately, but I’m definitely leaning toward it is doing more than I realized.
I plan to as for an increase in my dose from 3 to 4.5mg at my next appointment.

jesslily | @jesslily | May 8 8:37am

In reply to @suetex "Wont leave home without it. If you have any kind of autoimmune disease that involves diarrea..." + (show)

@suetex can you say more? Do you take on a schedule or as needed to control symptoms (like diarrhea?) Thanks!

suetex | @suetex | May 8 4:51pm

It does alot more than that. Please read about it

jesslily | @jesslily | May 9 1:36am

In reply to @suetex "It does alot more than that. Please read about it" + (show)

@suetex I've read a ton about it, and trialed it for three months. No problem if you don't want to say more.

livininthestix | @livininthestix | May 9 6:10am

I have some weird stuff going on with no answers. They think it could be autoimmune but my bloowwork says different. Just had 3 cm lymph nodes taken out of my armpits for biopsy. Nodes malignancy no infection no bacteria. They said they were reactive. I have lost 53 lbs without trying. I was put on LDN a few weeks ago as well as prednisone. I am able to function a heck of a lot better. I still have drenching night sweats every night but the pain is much better. I started on 1.5 mg a day for a week then 3mg a day for a week and now 4.5 mg a day. No real side affects for me. That's a win in my book. I will keep you posted but so far LDN is a keeper for me. Insurance won't cover it though

roslynroslyn | @roslynroslyn | May 9 7:38am

In reply to @livininthestix "I have some weird stuff going on with no answers. They think it could be autoimmune..." + (show)

@livininthestix did you use liquid form? It’s not too expensive.

livininthestix | @livininthestix | May 9 7:56am

In reply to @roslynroslyn "@livininthestix did you use liquid form? It’s not too expensive." + (show)

@roslynroslyn mayo sent me liquid over a year ago but I never really got to take it for long as I had to have my tonsils taken out and had to go on painkillers for that surgery. I take 1.5 mg pills 3 x a day currently

vostie | @vostie | May 9 8:13am

In reply to @jesslily "@suetex can you say more? Do you take on a schedule or as needed to control..." + (show)

@jesslily you take it every day. It took me about two months to work up slowly to a dose that started to minimize symptoms. You cannot take LDM if you regularly need pain medications as it blocks the receptor and you will not get pain relief. For me, my inflammation, pain, shortness of breath, skin breakouts, fatigue and more have all minimized and it has gotten better as I raised the dose. I am now at 5 mg per morning and have more energy and ability to do things than I have in 6 years.

roslynroslyn | @roslynroslyn | May 9 8:49am

In reply to @livininthestix "@roslynroslyn mayo sent me liquid over a year ago but I never really got to take..." + (show)

@livininthestix I was on it for a couple of years for Lyme disease. Didn’t really help. That was years ago. Now I have multiple health issues and my rheumatologist suggested it again for Raynauds. Should help MCAS if all goes well.

livininthestix | @livininthestix | May 9 9:44am

In reply to @roslynroslyn "@livininthestix I was on it for a couple of years for Lyme disease. Didn’t really help...." + (show)

@roslynroslyn I have raynaud's as well according to most doctors but some say no I don't have it. My toes curl uncontrollably and its pretty bad. The LDN has helped with the cold toes and fingers though. Like really helped that part of it. Hope some of .y experiences help you feel better