I have some weird stuff going on with no answers. They think it could be autoimmune but my bloowwork says different. Just had 3 cm lymph nodes taken out of my armpits for biopsy. Nodes malignancy no infection no bacteria. They said they were reactive. I have lost 53 lbs without trying. I was put on LDN a few weeks ago as well as prednisone. I am able to function a heck of a lot better. I still have drenching night sweats every night but the pain is much better. I started on 1.5 mg a day for a week then 3mg a day for a week and now 4.5 mg a day. No real side affects for me. That's a win in my book. I will keep you posted but so far LDN is a keeper for me. Insurance won't cover it though