GLP-1 Drugs Causing Arrythmias

For me, I had my first AFib episode 24 hours after I got my shot. Then had another episode the following week 24 hour after I took my shot of Zepbound. Maybe it was purely coincidence or the Zepbound brought it on. Now I'm on Eliquis and waiting for my cardiologist appointment. Holding off on the Zepbound for now. Super frustrating.

I started taking semaglutide about 5 months ago. During the last 30 days on semaglutide, GLP-1, my dosage was increased. I’ve lost about 20lbs on it. I had a history of Afib and 7 years ago had a heart ablation because I didn’t want to be on blood thinners and heart rate meds for the rest of my life. I’ve had no reoccurrence of Afib for 7 years. All of a sudden last month I went into persistent Afib. I went to urgent care and have spoken to a few doctors and no one seems to know anything about a relationship between GLP-1 and Afib. Everything on the internet says GLP-1 should actually help with AFIB because of weight loss. I stopped taking Semaglutide 2 weeks ago but am still in AFIB. I will be seeing a Mayo cardiologist in a few weeks.
Anyone else have any experience with GLP-1 and AFIB

https://pmc.ncbi.nlm.nih.gov/articles/PMC9403613/
This very recent analysis suggests there is no causal link between GLP-1 agonist usage and cardiac arrhythmias.

@gloaming I sincerely hope that this is true. I started Ozempic 6 weeks ago to hopefully help my heart failure issues as well as the need to lose some weight to improve my health status. It's been tough dealing with some of the side effects, but plan on continuing with the Qzempic.

@joyh We both hope I'm right, Joy, but I hope we both continue to keep our ear to the ground. Science, and it's advice-givers, tend to be highly mobile these years about the latest advice and findings, and I try hard to watch a variety of videos from different 'influencers' and read a variety of sources to ensure I can paint myself a reasonable ...and safe...prescription for me to keep following or to change to. In case it's news to you, was to me until about 10 months ago, some people develop moderate to severe problems, side-effects, to a drug used to reduce the risk of stroke in people with atrial fibrillation, one I take called Eliquis. I initially responded that it was well tolerated by pretty much everyone and that I had never heard of leg and muscle pain, or whatever the purported link the asker was proposing. Turns out I was wrong, and had several posters correcting me! Some people cannot take apixaban and still feel like living. I hope it's not true for you and Ozempic.

I started taking semaglutide about 5 months ago. During the last 30 days on semaglutide, GLP-1, my dosage was increased. I’ve lost about 20lbs on it. I had a history of Afib and 7 years ago had a heart ablation because I didn’t want to be on blood thinners and heart rate meds for the rest of my life. I’ve had no reoccurrence of Afib for 7 years. All of a sudden last month I went into persistent Afib. I went to urgent care and have spoken to a few doctors and no one seems to know anything about a relationship between GLP-1 and Afib. Everything on the internet says GLP-1 should actually help with AFIB because of weight loss. I stopped taking Semaglutide 2 weeks ago but am still in AFIB. I will be seeing a Mayo cardiologist in a few weeks.
Anyone else have any experience with GLP-1 and AFIB

I don't have experience in this, but I do know that there must be a close causal link established in literature before one should begin to speculate about such links. There is the 'post hoc, ergo propter hoc' fallacy in thinking that, I got drunk last night, but I woke up with a tattoo. It must mean that drinking caused me to break out in a tattoo.

People try something novel and later experience an unwanted or unpleasant episode of some kind of corporeal behaviour. Unless there can be a direct causal link, one should assume that there's at least the same probability that the episode was going to happen without the novel introduction.

About the recurring AF after 7 years - this is exceedingly common, even among AF sufferers who DON'T take GLP-1. It has been known for years that AF is a progressive disorder. Even after an apparently successful ablation (the patient is free from arrhythmias for one full year after the procedure), that same patient may find that they're back in AF the next month...Month #13. Or, it might take three or six years. A surprisingly, dismayingly, large number of all ablated AF sufferers will need at least a touch-up ablation at some point in the future. Again, it's exceedingly common, and doesn't have to be associated with GLP-1 usage. I t has to do with the heart developing new re-entrant foci at places other than where the previous ablation allowed the intrusion of electrical impulse into the left atrium.

I started taking semaglutide about 5 months ago. During the last 30 days on semaglutide, GLP-1, my dosage was increased. I’ve lost about 20lbs on it. I had a history of Afib and 7 years ago had a heart ablation because I didn’t want to be on blood thinners and heart rate meds for the rest of my life. I’ve had no reoccurrence of Afib for 7 years. All of a sudden last month I went into persistent Afib. I went to urgent care and have spoken to a few doctors and no one seems to know anything about a relationship between GLP-1 and Afib. Everything on the internet says GLP-1 should actually help with AFIB because of weight loss. I stopped taking Semaglutide 2 weeks ago but am still in AFIB. I will be seeing a Mayo cardiologist in a few weeks.
Anyone else have any experience with GLP-1 and AFIB

Interesting comment from Gloming about Eliquis. I am thankfully off all drugs after second ablation except Eliquis. But have continued lower leg issues and numbness in my feet. Also suffer from severe depression which is out of caracter for me but I can't shake. Could it be related to. And Gloming have you continued on Eliquis