Has anyone tried Ketamine for depression?

Posted by kelster69 @kelster69, Aug 8, 2020

Hi. My depression is intolerable right now. I started ketamine infusion therapy last August. It helped initially, but it has not really worked for me in about 7 months. I still went to the same clinic for 11 months, which I'm learning is a ketamine mill. I spoke with another doctor/clinic who does intramuscular ketamine treatments and who monitors dosing and patients' reactions very carefully during the treatment (my former clinic did not at all). I swore I wouldn't try ketamine again, after this last run failed and seemed to make me even more depressed. But I have some hope with this new clinic who seems to know what they're doing. I am at the end of my rope here; very depressed. I'm wondering if anyone else on here has experience with this treatment?

Interested in more discussions like this? Go to the Depression & Anxiety Support Group.

Profile picture for tbb3512 @tbb3512

I'm having trouble finding an antidepressant that works for me. Has anyone tried Spravato treatments? Thanks!

Jump to this post

I started Spravato mid 2024. I wasn’t sure if it was really working or not for a while. Because my depression has a lot to do with my pain. After I stopped because it was a new year and I was having another surgery. I was feeling slightly better, but my biggest problem. Is I have absolutely no energy and I’m tired all the damn time. I’ve been saying I felt pretty good and I did. But the fact that I still can’t get anything done around my house like I used to is killing me. This summer has been the worse ever. I’ve been married for 25 years this year. My husband is a complete ass he’s no help what so ever. You would think he would help to make things better on me. But hell no. He’s had it good for over 15+ years. I have always done all the cooking, cleaning and ALL THE YARD WORK. Because I loved doing that stuff. But now I can’t because of back which needs surgery now. I’m sorry I’m getting off track. But a few months ago my depression took a total dump. And I was able to go back to Spravato. Which is helping one part of me but the other parts are still hurting. If that helps anyone.

REPLY
Profile picture for tbb3512 @tbb3512

I'm having trouble finding an antidepressant that works for me. Has anyone tried Spravato treatments? Thanks!

Jump to this post

Can I get some feedback from anyone who has done Spravato ?

REPLY
Profile picture for UCFsig85 @ucfsig

Can I get some feedback from anyone who has done Spravato ?

Jump to this post

I have not yet been able to find a doctor that will prescribe spravato to me. It is supposed to be very helpful with pain. Normally, at the pain goes away so does a lot of depression. Good luck with your search. I would definitely try it if I could

REPLY
Profile picture for tbb3512 @tbb3512

I'm having trouble finding an antidepressant that works for me. Has anyone tried Spravato treatments? Thanks!

Jump to this post

I started Spravato treatments in late 2023 and currently get 2 treatments per month. For me it works very well. Shortly after starting, the debilitating weighed down feelings of depression lifted. I would highly recommend it. Fortunately my insurance covers it. I would encourage those with treatment resistant depression to discuss option with their mental health provider.

REPLY
Profile picture for michaelhall @michaelhall

I got real aggressive for some reason

Jump to this post

@michaelhall . did the treatments help you:?
?

REPLY
Profile picture for Mary Klepper @marylessard

I started IV ketamine in early Sept for TRD (treatment resistant depression). I'm 56 and have been treated with most everything out there since I was 21 - some successes along the way but nothing sustaining. I was in hospital (Rochester, MN - Mayo) in 2023 for suicidal ideation/had 14 ECT treatments, and had very significant memory loss - almost lost my job as a Mayo employee because of it. Fortunately, I work in a very compassionate department, and they were patient as I recovered my cognitive skills. Even though the ECT helped for a while, the depression returned, and I needed help once again. The IV Ketamine Clinic has CHANGED MY LIFE. It's a whole new world. Instant change - miraculous - and I mean SAME DAY. I wish that it worked for everyone like it has for me. I have never felt so good and well-adjusted. I have had maybe 8? treatments and I go every other week now, soon to be once a month. But I can't imagine a nasal treatment - getting a "full" dose in one shot...I enjoy the 40-minute infusion and have had zero side effects: no disassociation, nausea, headaches - nothing. I've 'tried' to go to that 'dark place' in my head - the suicidal 'room' where I don't want to live anymore - and I can't even find the door...it is unreal. The only barrier I had in securing treatment was that I am a recovering alcoholic/drug addict. I've been sober for almost 25 years and have quality sobriety, and that was a requirement for treatment. The feeling I get during treatment is not like being drunk; I am just utterly so happy; I can't explain it. I would suggest anyone with TRD to try it. Mayo Rochester is where I have been treated - Dr. Balwinder Singh. They have been treating patients for over ten years. God Bless you all - don't give up.

Jump to this post

@marylessard +I have had similar issues. Totally drug resistant - I think the VA has administered over two dozen in the last two years. Then I had 12 ECT treatments 6 bilaterial and 6 multilateral no relief whatsoever, in fact my anxiety and depression are worse. The VA offers Ketamine in some of this health centers, but I have not been successful in arranging anything with them, How does Mayo work? and What is the cost? Does insurance pay anything?
MICHAELREX

REPLY
Profile picture for tbb3512 @tbb3512

I'm having trouble finding an antidepressant that works for me. Has anyone tried Spravato treatments? Thanks!

Jump to this post

It’s becoming increasingly clear that ECT is not going to work for my depression. Is anyone familiar with failure rates of Ketamine?

REPLY
Please sign in or register to post a reply.