Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Posted by dougs72 @dougs72, Jun 22, 2024

Has anyone ever been on Duloxetine (Cymbalta) for nerve pain? I've had 2 doctors push this on me. I know that the side effects can be terrible and getting off of it difficult as it requires titration. One time I remember taking one pill, and not liking the way it made me feel, so not taking any more, and still feeling the "weirdness" from it 2-3 days later. and that was only 30 mg Please pass along any experience or advice from this medication?

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In reply to @pbrowni25 "Thank you!" + (show)
@pbrowni25

Thank you!

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I was on Cymbalta 60 mg each night for 26 years after being diagnosed with Fibromyalgia, Chronic Fatigue and Coxsacki B enterovirus. I went off the Cymbalta several times during that time thinking it wasn't working for me but each time I went off my pain jumped by triple. I have had 6 spinal surgeries and still have bone spurs and herniated disks in my spine so I am in pain all the time. I went off the Cymbalta again about 2 years ago on my doctor's advice and since being off of it I have had no heartburn (which I suffered with for all those 26 years and had to take Nexium for). I am in more pain than I was in when taking the Cymbalta but at least I am now off of two medications. I was also taking 600 mg of Gabapentin every night for the pain and now I am down to 300 mg. I am living with the pain and it isn't fun but there are only so many medications one can take and they all have side effects. If one can get off of all but essential medications like thyroid, diabetes, heart etc. you will be better off.

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@lilly71

I use it for anxiety and depression. My neurologist said it should help neuropathy but it doesn't for me

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Hi. I was given a prescription for Cymbalta too. I haven’t started taking it. Did you feel weird in the beginning? I’m on a different antidepressant, and will be slowly going off of that & will be on cymbalta. I have very painful neuropathy & numbness in my legs & feet. Im borderline diabetic.
I also have Fibromyalgia & Chronic fatigue.
I need to walk but I’m in so much pain and my balance is way off. It’s a catch 22. Very frustrating… I hope you are doing better. 😊

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@luvrofthelord

I was on Cymbalta 60 mg each night for 26 years after being diagnosed with Fibromyalgia, Chronic Fatigue and Coxsacki B enterovirus. I went off the Cymbalta several times during that time thinking it wasn't working for me but each time I went off my pain jumped by triple. I have had 6 spinal surgeries and still have bone spurs and herniated disks in my spine so I am in pain all the time. I went off the Cymbalta again about 2 years ago on my doctor's advice and since being off of it I have had no heartburn (which I suffered with for all those 26 years and had to take Nexium for). I am in more pain than I was in when taking the Cymbalta but at least I am now off of two medications. I was also taking 600 mg of Gabapentin every night for the pain and now I am down to 300 mg. I am living with the pain and it isn't fun but there are only so many medications one can take and they all have side effects. If one can get off of all but essential medications like thyroid, diabetes, heart etc. you will be better off.

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Thanks. I agree. The less meds the better. I have to take a blood thinner because I had a pulmonary embolism 1 yr ago. It came out of nowhere. I was sick for a month & went to 4 different Drs. No one diagnosed me correctly until I ended up in the emergency room and could not breathe. It was a nightmare.

Trying to get off of Effexor has been a problem too. I’m Glad you are off the Antidepressants. My Dr wants me to take Cymbalta instead. I don’t want to be on anything. I’m used to being in pain. I just live with it.

I fell & Fractured my back 2 yrs ago. I already had back problems, degenerative disc disease & scoliosis. I have had Fibromyalgia for 30 years, Chronic fatigue & migraines etc. I also have very painful neuropathy Not diabetic It’s not fun growing old. I haven’t been the same since I broke my back. Take care

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I’ve taken Duloxetine 60mg for almost two years. Absolutely no problems with it. If it is what is keeping my pain from FM, CF, nerve pain from diabetic neuropathy and pinched nerves in my back from an accident, then I will continue taking it. I’m still 5 pain level every day but that is a relief from 10+ before. I don’t think Duloxetine has anything to do with my headaches and migraines but I take Magnesium Citrate for that. It also helps my RLS. Anything to lower my pain is good in my book. I just upped Pregabalin to 100mg in morning and 200mg at bedtime. I am finally sleeping more than 3 hours a night. The RLS, neuropathy, nerve pain, arthritis bone and muscle pain disappears as I drift off to sleep. Such a joy as I have spent so many years going 3-4 days without sleep and then only getting a few hours of Benadryl or sleeping pill induced sleep. I do feel tired during the day and am told to take naps but I find daytime sleeping difficult to do. Going to try it though. I’m 70 years old and I have read that seniors should nap during the day as nighttime sleeping becomes harder to do.

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@celia16

I share your concern. I have the bottle of meds in my cabinet. I’m preparing to start it. Dreading it….but I have to try it, before my insurance will cover Lyrica.
And, Cymbalta may actually serve me better. Idk.

I’m ambivalent. I’ve read so much about it. Different people have different experiences. What I know is that my intermittent burning is excruciating and I can’t tolerate it long term. I’m scared and looking for answers, since my only diagnosis right now is Vitamin B12 deficiency.

Klonapin does help, but that’s a short term thing. If my burning continues, I’ll need something daily. I wish there was something to take on as as need basis, that’s not a Benzo, since I feel great on days there isn’t burning.

When do you think you’ll start and what symptoms did you have trouble with?

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Hi I have burning also where are you getting your burning? If you don't mind me asking and how long have you had it? They put me on duloxetine too

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