Getting off of Seroquel

Posted by anniegk @anniegk, Jun 8, 2018

I have been on 300 mgs. Seroquel ER for over a year for augmenting my antidepressant which is 45 mgs. Of Mirtazapine. I decided to try and get off of the Seroquel. I was on 300mgs ER (extended release). I titrated down to 250 mg ER for 2 months without too many problems.than i titrated down to 200mgs ER just 5 days ago. My plan is to try to titrate off using ER tablets. My thinking is that perhaps the drug will remove its self from my system more gradually. I have had some nausea and a couple of episodes of diarrhea. I also have a very irregular heart beat and was started on 60 mgs of Propranolol ER (extended release) 4 weeks ago. It seems to be helping my heartbeat. I have wondered if the nausea and light headness is from the Propranolol, a Beta Blocker, or the dose reduction of the Seroquel. I also wonder if the way iam titrating the Seroquel is safe. My doctor says it will only take a couple of weeks...I think that is too fast of a taper after being on a drug for over a year. What do you think?

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What if you are taking only .25 Seroquel?

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I'm not sure how long I've been on Quetiapine. I take 200mg every night. I also soundlike I'm drunk all the time! I'm slurring my words really badly especially around people I don't talk to on a regular basis. My doctor suggested coming off of it. But didn't help me. I'm seeing him again on Monday Nov. 25th. But I really want to start coming off it now! I was thinking of first cutting myself down to 175mg. Just coming down 25mg a couple weeks at a time.... I know I haven't been on this drug for a year but more than 6 months. My diagnosis is Bipolar type 1 and general anxiety Can anybody help?

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Be sure to consult with your doctor.

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Profile picture for laurafay86 @laurafay86

Be sure to consult with your doctor.

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Of course I was just looking for opinions

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Profile picture for jennymarie45 @jennymarie45

Of course I was just looking for opinions

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Hi, @laurafay86 - welcome to Mayo Clinic Connect. That is rough you've had the slurring side effect you've described from your meds.

You mentioned your doctor suggested getting off the quetiapine. Did he mention other alternatives for you?

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All I know is that I'm seeing my doctor Monday the 11th. The original appointment was the 25th....thank goodness it's Monday!!

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I was on Seroquel after having good luck with Abilify but my body couldn’t tolerate it and one of the side effects I got from that was a pretty significant tremor. So we tried Remeron but I’m a chronic migraine sufferer and it made my headaches worse. So they put me on Seroquel and I thought I’d found the answer to my depression and insomnia. However, I now have Tardive Dyskinesia which shows up as strange mouth movements and toe snapping especially when I’m anxious. So I had to go off of the Seroquel cold turkey. And now I’m currently on the search for help with my insomnia that isn’t addicting like most of the benzodiazepines. However, I’m stuck with the after effects and/or side effects from the Seroquel. You didn’t really say why you are on it so I can’t speculate about your side effects or withdrawal but I can give you my experiences. Good luck to you.

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I was trying to get off of Seroquel. Was on 25mgs for insomnia. So tried Trazodone for 2 days. I got so sick with side effects such as nausea, weakness, dizziness, constipation, tremors and suicide thoughts. I have been taking .25 of xanax occasionally at night to with sleep.
I am a Type 2 diabetic with microvascular brain disease. I am getting very discouraged on how sick I have been feeling. The insomnia scares me and I can not get rid of it.

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Xanax .25 mg is almost negligible and if it helps you sleep I would think that your physician would be in agreement. With that said, most physicians want to stay as far away from Scheduled drugs as possible but will freely put you on anti-psychotics, anti-depressants etc, which have horrible side effects and even worse effects when attempting to stop them, and all this at the expense of the patient! If you don't get the sleep that you need you cannot manage your other issues well. Sleep in itself is one of the best therapies there is.

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Hello

I am presently taking 150 mg of Seroquel at night along with 7.5 mg of Remeron and 7.5 mg of buspirone. I take 50 mg of Seroquel in the morning. I would like to wean off of Seroquel since I am experiencing malaise, confusion, brain fog, difficult with focusing my eyes and other issues. What would you suggest for a weaning schedule for the Seroquel?

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