1. < Epilepsy & Seizures

Zonisamide and intestional blockage

Posted by minajo @minajo, Feb 27 10:30am

My daughter (48, nonverbal, autistic, epileptic)
was just hospitalized for intestinal impaction and has been on Zonisamide for 18 mo.. also Seroquel ( 8 years,low dose)and wondering if anyone has had this happen? She was seriously ill, almost needed surgery..
Thank you

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Leonard | @jakedduck1 | Feb 28 3:52am

@minajo
Isn’t Seroquel more likely to cause constipation than Zonisamide? Did the doctor say the Zonisamide was the cause?
Take care,
Jake

REPLY
1 reply
Chris Gautier OR Santosha | @santosha | Feb 28 5:50am

@minajo
Good Morning,
I am sorry to hear that!
According to my gastroenterologist, all neurological medications have a direct impact on the gut because they cause microbiota imbalance. As the doctor said, one has to evaluate the costs versus the benefits of those medications, because they have consequences.
Early last year, I was diagnosed with SIBO (small intestinal bacterial overgrowth) caused by the AEDs I have taken for 3 years. I am still treating my SIBO, it is not a fast process. My mother who has Alzheimer's has also been having consequences of the neurological medications she has been taking.
It is sad to see that neurologists and epileptologists do not tell us about the consequences of taking AEDs and other neurological medications!
Today my epilepsy is being treated with medical cannabis, trigger management, and diets and I am far better.
If you have not already done it, I recommend seeing a gastroenterologist doctor.
Wishing you and your daughter all the best.
Chris (Santosha)

REPLY
1 reply
minajo | @minajo | Feb 28 6:12pm
In reply to @jakedduck1 "@minajo Isn’t Seroquel more likely to cause constipation than Zonisamide? Did the doctor say the Zonisamide..." + (show)
@jakedduck1

@minajo
Isn’t Seroquel more likely to cause constipation than Zonisamide? Did the doctor say the Zonisamide was the cause?
Take care,
Jake

Jump to this post

Yes, Seroquel does that but my daughters weight gain, kidney issues, ammonia started month after the Zonisamide started.. she's been on Seroquel for some time and never had an impaction till now.. hard to get answers ..
Thanks

REPLY
minajo | @minajo | Feb 28 6:16pm
In reply to @santosha "@minajo Good Morning, I am sorry to hear that! According to my gastroenterologist, all neurological medications..." + (show)
@santosha

@minajo
Good Morning,
I am sorry to hear that!
According to my gastroenterologist, all neurological medications have a direct impact on the gut because they cause microbiota imbalance. As the doctor said, one has to evaluate the costs versus the benefits of those medications, because they have consequences.
Early last year, I was diagnosed with SIBO (small intestinal bacterial overgrowth) caused by the AEDs I have taken for 3 years. I am still treating my SIBO, it is not a fast process. My mother who has Alzheimer's has also been having consequences of the neurological medications she has been taking.
It is sad to see that neurologists and epileptologists do not tell us about the consequences of taking AEDs and other neurological medications!
Today my epilepsy is being treated with medical cannabis, trigger management, and diets and I am far better.
If you have not already done it, I recommend seeing a gastroenterologist doctor.
Wishing you and your daughter all the best.
Chris (Santosha)

Jump to this post

With my daughter being nonverbal autistic, just getting the impaction addressed during hospitalization was priority, she had psychotic episode maybe from Ativan but will see g. i after she is stable.. has had colonic interposition for several years with no ill effects, so very hard to fully diagnose with her comorbid autism and epilepsy!
Thanks

REPLY
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