Wegovy then switched to a compounded formula of semaglutide

Posted by bhb30602 @bhb30602, Jun 9 12:36pm

A month ago, my PCP gave me a free sample of .25 Wegovy (month's supply) and I take the 4th jab tomorrow. Since my insurance won't cover Wegovy, he prescribed a compound formula of semaglutide with pyridoxine and glycine and increased the dose to .50mg. The pyridoxine (B6) for possible nausea and glycine to help maintain muscle. I've checked out the compound pharmacy on BeSafeRx and everything seems to check out as reputable.
Has anyone started on Wegovy then switched to a compounded formula of semaglutide and if so, what was the transition like and have you lost any weight?
Any info is appreciated.

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Profile picture for loresull @loresull

Hello,

I tried wegovy last year and it didnt work like I hoped, since I am not diabetic my weight loss was slow and only like 15 to 20 lbs. I did lose mostly muscle and even fell and damaged my meniscus. After a year my weight loss was only like 20 lbs, which I gained back. I was thinking of trying a different one, it is called Zepbound (tirzepatide). any thoughts? this time I will be excersisng and doing yoga. I am hoping to lose aprox 30 lbs by december.

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@loresull
Hi there, I feel like I’m a professional dieter which gives you the story of all the weight loss I’ve done and weight gain. After gaining almost 80 pounds after an accident and being wheelchair bound for two years, I finally upped my exercise. My doctor sent me down and we figured out how many calories I needed to maintain the weight I was at then we removed 500 cal. He was kind of shocked that I needed to drive to 1000 cal to kickstart my system into losing weight. It’s not many calories so I had to make it extremely nutrient dense. Any grains or whole grains, I would marinate chicken and have chunks of it in a baggie in the fridge to grab for snacking or throw on a salad. Same thing with some steamed shrimp, etc. I would make a gallon baggie of salad with every vegetable I could think of and I ate that once my breakfast of one egg, one egg white and a little cottage cheese had passed. I didn’t eat anything else until that salad was gone and it really did get tiring, but it also filled me up and kept my system running. We’re all vegetables have lots of needed nutrients in them that we need to keep from getting depleted. I enjoyed a small medium potato, actually quite often because of the potassium. It’s a starch not a carb really .
Anyway, it took about three weeks before my body finally kicked in to weight loss and from that point on it was pretty easy. I did use protein bars occasionally and I would slice them up in 1/6 of a bar and keep them in the freezer. I’m an anxiety eater so I had to have food to munch on and I prepped cucumber chunks, celery, sticks, and anything crunchy like that to have on hand. It took me a year and a half to lose the weight but I have kept it off. I probably have about 1200 cal a day now. I can’t do a lot of exercising because of the damage from the boating accident which pretty much mangled my right lower leg. Long walks are out for me so is riding a bicycle but I can push a mean vacuum cleaner lol
Anyway, you have to find out how many calories you maintain your weight at then you’ve gotta remove 300 maybe to start and if it’s feasible remove 500 cal from your allowance then you will lose weight. I guarantee it. If I were to have had access to a GLP one at the time I would have used it absolutely but with the above. If you don’t change your behavior, you will just gain the weight back. Of the GLP ones I would certainly use Terzepitide compounded with B6. I think. Search out a good compound Pharmacy. Big Pharma has got these things so high priced under brand name. It cuts out most people. I helped my daughter and it cost us $50. Per 10 milligram units of Terzepitide. I mixed with sterile, prescription grade micellar water and all sterile syringes and protocols. She’s lost 20 pounds with the cost of $100.
I understand everyone’s concerns and FDA likes nothing better than to you into submission, but there are some great Terzepitide peptide resources available GLP 1 peptides reconstituted with sterile pharmaceutical micellar water is a game changer for those that can’t afford the big box and whose insurance doesn’t cover weight loss. It worked just the same as my friend who is using the brand pharmaceutical pens. Cost her close to $4000. But do your homework and be safe and good luck on your weight loss journey.

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Profile picture for 3oakley2 @3oakley2

I understand that totally. We have no kids but our girls are our family. We lost our 2 girls within months of each other..it was devastating. They are family. We waited almost 2 years to get another dog..then another so we have 2 girls again! That’s a normal grief reaction. Take your time and grieve the pups, no reason to hurry it. I can now laugh and smile and think of our girls but it took awhile..a long while. One was my heart dog, we called her.
Did your Dr give you something for nausea? Zofran helps a lot of people. I take my shot at night..10 pm maybe I slept thru it. I didn’t have nausea except a couple times when I ate too much like a whole steak…that was the last time. You will learn what you can and can’t eat anymore. I just felt like I had gorged myself at a buffet all the time. I would eat a couple bites and I couldn’t eat any more. I thought that is how these drugs worked, I thought everyone felt like that and that’s how you lost the weight. I couldn’t hardly get up and go places without being dizzy and faint from not eating. I talked my endo into reducing my dose and we have both been surprised that now I can eat with no problem and still no food noise or cravings. I get hungry once in awhile but I have been told hunger is not your enemy and it isn’t. Even if I’m hungry i don’t go crazy. The journey has been good for me. I am thankful for the compound because the starting dose pen I would have had to stop. I hope you can find a local compounding pharmacy if that’s what you choose. I was familiar with them because one of our pups had bladder cancer and the other one had kidney failure, they were small so we had to use compounded meds with them. As a nurse I was leery at first but I am very comfortable after using this since July of last year. I had no choice, my gastro said Do meds, surgery or die early. I wish you good luck! PS..I have just started into therapy after 21 years, trying to find other coping mechanisms, other than eating! Only my 3rd visit so hopefully it will help.

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@3oakley2 - I'm so sorry about the loss of your dogs. Wondering how you are doing with that and also with your compounded tirzepatide (Zepbound)?

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Profile picture for loresull @loresull

oh this is great news! i will let my endo know. i do snore like a trucker.... maybe i should have my husband record me!
tyvm!!!

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My husband, bless his little heart, recorded me snoring and stopping breathing so that’s what got me to the sleep study and a CPAP machine. But it always isn’t readily noticeable. The cardiologist was having a hard time regulating my husband’s BP and I asked him about a sleep study and yep he needed it but I had never and to this day have never noticed him stop and start breathing but it’s helped him tremendously. And sleep is when your body repairs itself. When menapausal some of us didn’t and don’t get good healing sleeps.

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Profile picture for 3oakley2 @3oakley2

A sleep study that your Dr can order. Snoring is a sign. Zepbound has been approved for treatment of obstructive sleep apnea now. That doesn’t mean that your insurance has to approve it you would just have to ask your insurance. Sometimes the insurances want you to do steps A, , and C before they give a PA..that’s a question you can ask them.

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oh this is great news! i will let my endo know. i do snore like a trucker.... maybe i should have my husband record me!
tyvm!!!

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Profile picture for 3oakley2 @3oakley2

I understand that totally. We have no kids but our girls are our family. We lost our 2 girls within months of each other..it was devastating. They are family. We waited almost 2 years to get another dog..then another so we have 2 girls again! That’s a normal grief reaction. Take your time and grieve the pups, no reason to hurry it. I can now laugh and smile and think of our girls but it took awhile..a long while. One was my heart dog, we called her.
Did your Dr give you something for nausea? Zofran helps a lot of people. I take my shot at night..10 pm maybe I slept thru it. I didn’t have nausea except a couple times when I ate too much like a whole steak…that was the last time. You will learn what you can and can’t eat anymore. I just felt like I had gorged myself at a buffet all the time. I would eat a couple bites and I couldn’t eat any more. I thought that is how these drugs worked, I thought everyone felt like that and that’s how you lost the weight. I couldn’t hardly get up and go places without being dizzy and faint from not eating. I talked my endo into reducing my dose and we have both been surprised that now I can eat with no problem and still no food noise or cravings. I get hungry once in awhile but I have been told hunger is not your enemy and it isn’t. Even if I’m hungry i don’t go crazy. The journey has been good for me. I am thankful for the compound because the starting dose pen I would have had to stop. I hope you can find a local compounding pharmacy if that’s what you choose. I was familiar with them because one of our pups had bladder cancer and the other one had kidney failure, they were small so we had to use compounded meds with them. As a nurse I was leery at first but I am very comfortable after using this since July of last year. I had no choice, my gastro said Do meds, surgery or die early. I wish you good luck! PS..I have just started into therapy after 21 years, trying to find other coping mechanisms, other than eating! Only my 3rd visit so hopefully it will help.

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Thank you for understanding, my doggies are my life. we did everything for them and yes it is uber devastating, i still find myself crying and not able to deal. i so thankful for my kittie Ellie, we rescued her last year, i now think it was a sign, she is here to help me thru this horrible loss. Both our doggies also had cancer. she had spleen and he had pancreatic.
I do have zofran, thank you for the reminder. I will take it next time i have that horrible feeling.
We bought protein shakes from costco and they have been a huge help, since I am also a vegetarian and do not drink milk we found some that are vegan and help when im in a rush.
i have been thinking about therapy, ive done it before for childhood ptsd maybe i need to revisit. good luck w therapy, please keep me posted!!! it gives me hope!!! i keep repeating time heals. its going to be a year in october for Isabella and i'm so not ready.

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Profile picture for loresull @loresull

hmmm how would i know i have sleep apnea?
i am super menopausal, tmi sorry! and i snore a lot, but how did your insurance cover it?
maybe i can go that route! ty!

Jump to this post

A sleep study that your Dr can order. Snoring is a sign. Zepbound has been approved for treatment of obstructive sleep apnea now. That doesn’t mean that your insurance has to approve it you would just have to ask your insurance. Sometimes the insurances want you to do steps A, , and C before they give a PA..that’s a question you can ask them.

REPLY
Profile picture for loresull @loresull

sooo happy for you!!! this is fantastic!!! I will have to look into finding a compound pharmacy. I am on my first week of the tirzepatide and wow with the nausea and stomach upset. I find that if I drink lots of water and eat super healthy including veggies with my protein it helps. I used to be more motivated to move, but we lost our shihtzu girl last october and it literally broke me and then in May we lost our cavapoo. So I have been dealing with a lot of grief and emotions since we don't have human children, the doggies are our family. I have not been as active since her loss and I am still super depressed but at the same time I am starting to want to feel better about myself and I think that by working on my outside my insides will catch up. + I really want this to work permanently. I think that if I tacle it from both sides it will work, keeping fingers crossed!

Jump to this post

I understand that totally. We have no kids but our girls are our family. We lost our 2 girls within months of each other..it was devastating. They are family. We waited almost 2 years to get another dog..then another so we have 2 girls again! That’s a normal grief reaction. Take your time and grieve the pups, no reason to hurry it. I can now laugh and smile and think of our girls but it took awhile..a long while. One was my heart dog, we called her.
Did your Dr give you something for nausea? Zofran helps a lot of people. I take my shot at night..10 pm maybe I slept thru it. I didn’t have nausea except a couple times when I ate too much like a whole steak…that was the last time. You will learn what you can and can’t eat anymore. I just felt like I had gorged myself at a buffet all the time. I would eat a couple bites and I couldn’t eat any more. I thought that is how these drugs worked, I thought everyone felt like that and that’s how you lost the weight. I couldn’t hardly get up and go places without being dizzy and faint from not eating. I talked my endo into reducing my dose and we have both been surprised that now I can eat with no problem and still no food noise or cravings. I get hungry once in awhile but I have been told hunger is not your enemy and it isn’t. Even if I’m hungry i don’t go crazy. The journey has been good for me. I am thankful for the compound because the starting dose pen I would have had to stop. I hope you can find a local compounding pharmacy if that’s what you choose. I was familiar with them because one of our pups had bladder cancer and the other one had kidney failure, they were small so we had to use compounded meds with them. As a nurse I was leery at first but I am very comfortable after using this since July of last year. I had no choice, my gastro said Do meds, surgery or die early. I wish you good luck! PS..I have just started into therapy after 21 years, trying to find other coping mechanisms, other than eating! Only my 3rd visit so hopefully it will help.

REPLY
Profile picture for 3oakley2 @3oakley2

Do you happen to have sleep apnea? When I started last July ‘24 it was not a covered but now it is. My apnea has so improved I’m sure it wouldn’t cover mine now but I am going to ask next week when I see pulmonologist. Good luck!

Jump to this post

hmmm how would i know i have sleep apnea?
i am super menopausal, tmi sorry! and i snore a lot, but how did your insurance cover it?
maybe i can go that route! ty!

REPLY
Profile picture for loresull @loresull

Hi Lisa,
Thank you for your response, after using wegoy i also gained the weight back. its very frustrating. My endo agreed i should try tirzepatide, but it is sooo expensive!! for some reason my insurance does not cover it now, but they did cover wegovy a couple of years ago. my plan is to try it for a couple of months and also excersise every day. I did find a zumba class on youtube i like ... we will see!!! i think that if i motivate my brain this time it will be easier.

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Do you happen to have sleep apnea? When I started last July ‘24 it was not a covered but now it is. My apnea has so improved I’m sure it wouldn’t cover mine now but I am going to ask next week when I see pulmonologist. Good luck!

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Profile picture for 3oakley2 @3oakley2

I have been on compounded tirzepatide-zepbound for 14 months and lost over 100#. I have 20-30# yet to go. I was unable to tolerate the starting dose, couldn’t hardly eat. Talked the endo into decreasing my dose instead of increasing it. I’ve been doing 1.5mg every for a whole year. I use a compound pharmacy where I live. My endocrinologist gives me a compound. I can eat now but still have no food noise or craving. I know I am not typical but I work very hard at dieting. I count my protein and calories daily. Making sure I get fiber and enough fluids. I am moving more using resistance bands for strength. I’m 68 years old. Off many meds. Blood work is normal. Yay!!
One thing I have noticed in my GLP-1 groups that all telehealth companies are not equal. I would suggest if you don’t feel your compound is working to find a reputable compounding pharmacy and try another. I may end up with telehealth when I get on maintenance because I have a concierge endo because I had to find one to take care of my post cancer and that would prescribe me compounds. If you can find a compounding pharmacy in your city or near you to get your meds that is affordable it’s easier and they are easier to deal with if you have questions. Also the tirzepatide works two ways and has less side effects than the semaglutide. I sure wish you well. It’s a job. People don’t understand that the weight doesn’t fall off and you have to work at it! Sounds like you know what you need to do! Good luck!!

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sooo happy for you!!! this is fantastic!!! I will have to look into finding a compound pharmacy. I am on my first week of the tirzepatide and wow with the nausea and stomach upset. I find that if I drink lots of water and eat super healthy including veggies with my protein it helps. I used to be more motivated to move, but we lost our shihtzu girl last october and it literally broke me and then in May we lost our cavapoo. So I have been dealing with a lot of grief and emotions since we don't have human children, the doggies are our family. I have not been as active since her loss and I am still super depressed but at the same time I am starting to want to feel better about myself and I think that by working on my outside my insides will catch up. + I really want this to work permanently. I think that if I tacle it from both sides it will work, keeping fingers crossed!

REPLY
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