Treatment resistant depression help.

Posted by melbourneaussie69 @melbourneaussie69, Dec 10, 2024

I was diagnosed with Interstitial Lung Disease in September 2020, as time went on, I was lucky enough to receive a lung transplant. I have also dealt with chronic back pain for over 25 years. After my experience in hospital, I was left with PTSD and panic attacks. I was seeing a Psychiatrist and taking Mirtazapine, this seemed to have a negative effect on my behaviour and mood so I stopped taking it. In a search for help I tried many avenues only to be met with constant recommendations to take anti-depressants. Eventually I disengaged with the Psychiatrist and began medicinal cannabis. This has to be done carefully as it clashes with Tacrolimus. I have found it to be beneficial but not a magic bullet. Am I alone in having suicidal ideations after having a transplant? I should be grateful for having a second chance, but I am not.

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Profile picture for januaryjane @januaryjane

Ive been diagnosed with depression, anxiety, ptsd for over 20 years. I grew up with a lot of trauma and neglect. Ive never done ECT or the ketamine sprays, Im so afraid of them. Ive done a wide array of medications and therapy.
Im so lost right now, I can't seem to thrive, I am disabled because of it.
My mom is having cognitive decline so it's a lot of stress. We have a rocky relationship but she's still my mom.
We are not fighting as much which I like but I am so sad for her and feel helpless. I worry because my dad and brother dont.
So I feel stuck myself.

Not sure what to do when throwing meds at it isn't helping and therapy has me going nowhere right now.

There are very limited resources, no support groups, just AA. Im not sure how to find community, relearn to socialize and find a life for me again.

Should I try something else? Im at a loss

Jump to this post

Had 7 “doses” of Ketamine. What a waist! Just made me feel dizzy and “loopy”. Was advertised as anti-depression wonder drug. Hardly.

REPLY
Profile picture for januaryjane @januaryjane

Ive been diagnosed with depression, anxiety, ptsd for over 20 years. I grew up with a lot of trauma and neglect. Ive never done ECT or the ketamine sprays, Im so afraid of them. Ive done a wide array of medications and therapy.
Im so lost right now, I can't seem to thrive, I am disabled because of it.
My mom is having cognitive decline so it's a lot of stress. We have a rocky relationship but she's still my mom.
We are not fighting as much which I like but I am so sad for her and feel helpless. I worry because my dad and brother dont.
So I feel stuck myself.

Not sure what to do when throwing meds at it isn't helping and therapy has me going nowhere right now.

There are very limited resources, no support groups, just AA. Im not sure how to find community, relearn to socialize and find a life for me again.

Should I try something else? Im at a loss

Jump to this post

I very much know what you’re going through. I have treatment resistant depression along with complex PTSD, quiet BPD, and Dissociative Disorder. I actively tried suicide twice on SSRI’s, so I’m extra careful with anti-depressants. I’ve tried so many versions of therapy which did not work at all for me — then my current therapist introduced me to Internal Family Systems (IFS). It’s the only therapy that clicked for me.
I’m also getting lined up for EMDR (but I have no complete traumatic memories to resolve) and will be doing ECT in January. I am so exhausted from depression and suicide ideations that I will try anything at this point.

REPLY
Profile picture for januaryjane @januaryjane

Ive been diagnosed with depression, anxiety, ptsd for over 20 years. I grew up with a lot of trauma and neglect. Ive never done ECT or the ketamine sprays, Im so afraid of them. Ive done a wide array of medications and therapy.
Im so lost right now, I can't seem to thrive, I am disabled because of it.
My mom is having cognitive decline so it's a lot of stress. We have a rocky relationship but she's still my mom.
We are not fighting as much which I like but I am so sad for her and feel helpless. I worry because my dad and brother dont.
So I feel stuck myself.

Not sure what to do when throwing meds at it isn't helping and therapy has me going nowhere right now.

There are very limited resources, no support groups, just AA. Im not sure how to find community, relearn to socialize and find a life for me again.

Should I try something else? Im at a loss

Jump to this post

meds are ok till they stop working then what ?? getting off them is a nightmare they just dont work long

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Profile picture for tisme @tisme

meds are ok till they stop working then what ?? getting off them is a nightmare they just dont work long

Jump to this post

@tisme that’s what I was talking about on the sleep study, it’s not difficult to find the right medication to help you and when you do find help it’s a wonderful relief but eventually it just seems to stop helping and then you have to start again. I always feel like I’m going around in circles with the same problem.

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Profile picture for januaryjane @januaryjane

Ive been diagnosed with depression, anxiety, ptsd for over 20 years. I grew up with a lot of trauma and neglect. Ive never done ECT or the ketamine sprays, Im so afraid of them. Ive done a wide array of medications and therapy.
Im so lost right now, I can't seem to thrive, I am disabled because of it.
My mom is having cognitive decline so it's a lot of stress. We have a rocky relationship but she's still my mom.
We are not fighting as much which I like but I am so sad for her and feel helpless. I worry because my dad and brother dont.
So I feel stuck myself.

Not sure what to do when throwing meds at it isn't helping and therapy has me going nowhere right now.

There are very limited resources, no support groups, just AA. Im not sure how to find community, relearn to socialize and find a life for me again.

Should I try something else? Im at a loss

Jump to this post

Im on effexor cos I cant get off so what are other meds going to be like?

REPLY
Profile picture for                        @hopeseeker22

Had 7 “doses” of Ketamine. What a waist! Just made me feel dizzy and “loopy”. Was advertised as anti-depression wonder drug. Hardly.

Jump to this post

REPLY
Profile picture for januaryjane @januaryjane

Ive been diagnosed with depression, anxiety, ptsd for over 20 years. I grew up with a lot of trauma and neglect. Ive never done ECT or the ketamine sprays, Im so afraid of them. Ive done a wide array of medications and therapy.
Im so lost right now, I can't seem to thrive, I am disabled because of it.
My mom is having cognitive decline so it's a lot of stress. We have a rocky relationship but she's still my mom.
We are not fighting as much which I like but I am so sad for her and feel helpless. I worry because my dad and brother dont.
So I feel stuck myself.

Not sure what to do when throwing meds at it isn't helping and therapy has me going nowhere right now.

There are very limited resources, no support groups, just AA. Im not sure how to find community, relearn to socialize and find a life for me again.

Should I try something else? Im at a loss

Jump to this post

Everyone is different in their response to treatment. Ketamine aka Spravato made a significant positive impact after 30 years of different therapy/medication options. I have been on it since late 2024 and currently receive 2 treatments per month. I still do periodic therapy and have eliminated one Rx and am reducing dosage on another. I do not care for the 30-45 min of loopiness, but is worth the benefit for me.

REPLY
Profile picture for januaryjane @januaryjane

Ive been diagnosed with depression, anxiety, ptsd for over 20 years. I grew up with a lot of trauma and neglect. Ive never done ECT or the ketamine sprays, Im so afraid of them. Ive done a wide array of medications and therapy.
Im so lost right now, I can't seem to thrive, I am disabled because of it.
My mom is having cognitive decline so it's a lot of stress. We have a rocky relationship but she's still my mom.
We are not fighting as much which I like but I am so sad for her and feel helpless. I worry because my dad and brother dont.
So I feel stuck myself.

Not sure what to do when throwing meds at it isn't helping and therapy has me going nowhere right now.

There are very limited resources, no support groups, just AA. Im not sure how to find community, relearn to socialize and find a life for me again.

Should I try something else? Im at a loss

Jump to this post

I agree that Ketamine should be avoided. I have TRD. Have tried CBT, acupuncture, any number of antidepressants, a lot of therapists, Xanax, AND Ketamine. K just crap and absolutely zero help with anxiety, depression. Seemed psychedelic. I dunno; seemed like a legal way for crack heads to get high or whatever, tho I don’t know what “high” is. I tried legal medical marijuana. But never having used marijuana, tobacco or “recreational drugs” I probably didn’t do it right. The one time, I seemed to see MYSELF talking nearby with my wife about whether I actually “were there or not” or had “passed on” or something. Very gradually the drug (M) must have worn off and I kinda merged back to my actual self. Never tried it again. But still have the expired state of AZ card. Just FYI, what I take daily: Lexapro, Xanax only 1.5mg per day, Adderall XR 30mg in morning, Adderall IR 30mg around noon. Always tired but Adderall gives me maybe 5-6 productive hours a day. A former Dr. thought I had ADD & prescribed it maybe 25 years ago. Gave me energy without other noticeable side-effects. Maybe did hurt sleep if taken too late in the day. Had 2 sleep studies (bogus) and tried CPAP, also racket. I truly hope that you’ll find a positive outcome. Tom

REPLY
Profile picture for januaryjane @januaryjane

Ive been diagnosed with depression, anxiety, ptsd for over 20 years. I grew up with a lot of trauma and neglect. Ive never done ECT or the ketamine sprays, Im so afraid of them. Ive done a wide array of medications and therapy.
Im so lost right now, I can't seem to thrive, I am disabled because of it.
My mom is having cognitive decline so it's a lot of stress. We have a rocky relationship but she's still my mom.
We are not fighting as much which I like but I am so sad for her and feel helpless. I worry because my dad and brother dont.
So I feel stuck myself.

Not sure what to do when throwing meds at it isn't helping and therapy has me going nowhere right now.

There are very limited resources, no support groups, just AA. Im not sure how to find community, relearn to socialize and find a life for me again.

Should I try something else? Im at a loss

Jump to this post

Sorry to hear that you are feeling so bad. I went through many therapists until I found one that helped me. I have three conditions that complicated the diagnosis and treatment. It took two years to get to the heart of my diagnosis and then I had a better understanding of why I was so sick. I still get depressed, but not as often. I really think that I have to accept myself as I am and do the best that I can one day at a time. Self pity helps no one. Keep trying and never give up.

REPLY
Profile picture for                        @hopeseeker22

I agree that Ketamine should be avoided. I have TRD. Have tried CBT, acupuncture, any number of antidepressants, a lot of therapists, Xanax, AND Ketamine. K just crap and absolutely zero help with anxiety, depression. Seemed psychedelic. I dunno; seemed like a legal way for crack heads to get high or whatever, tho I don’t know what “high” is. I tried legal medical marijuana. But never having used marijuana, tobacco or “recreational drugs” I probably didn’t do it right. The one time, I seemed to see MYSELF talking nearby with my wife about whether I actually “were there or not” or had “passed on” or something. Very gradually the drug (M) must have worn off and I kinda merged back to my actual self. Never tried it again. But still have the expired state of AZ card. Just FYI, what I take daily: Lexapro, Xanax only 1.5mg per day, Adderall XR 30mg in morning, Adderall IR 30mg around noon. Always tired but Adderall gives me maybe 5-6 productive hours a day. A former Dr. thought I had ADD & prescribed it maybe 25 years ago. Gave me energy without other noticeable side-effects. Maybe did hurt sleep if taken too late in the day. Had 2 sleep studies (bogus) and tried CPAP, also racket. I truly hope that you’ll find a positive outcome. Tom

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@hopeseeker22 With all due respect, treatments for depression is tailored to the individual. Ketamine is not for everyone. Personally I do not care for the temporary psychedelic effect, but the results are worth it. In my case it only lasts 20-30 min. I wish you the best in your treatment journey.

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