Tezspire

Posted by kathleenkapes @kathleenkapes, Aug 16, 2023

My allergist feels my lungs are inflamed and recommends beginning Tezspire injections. The side effects seem awful.
Has anyone tried this?
I am on prednisone for 2 years for Polymyalgia Rheumatica probably caused by the COVID vaccine. The doctor believes that, as I taper prednisone, my lungs will become worse.
I also have osteoarthritis and fibromyalgia.

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I tried Tezspire and unfortunately fell at around the same time, not related. I experienced pretty bad back pain afterwards so cannot truthfully attribute this to Tezspire although that’s a main side effect. It helped my asthma tremendously but I stopped due to my pain. I’ve since had to get a hip replacement and will soon start Tezspire again. The side effects from Prednisone are probably worse for your body than Tezspire. You’ll never know unless you try. It was the only asthma medication that’s ever helped me. Good luck

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Profile picture for jazzygirl5 @jazzygirl5

I tried Tezspire and unfortunately fell at around the same time, not related. I experienced pretty bad back pain afterwards so cannot truthfully attribute this to Tezspire although that’s a main side effect. It helped my asthma tremendously but I stopped due to my pain. I’ve since had to get a hip replacement and will soon start Tezspire again. The side effects from Prednisone are probably worse for your body than Tezspire. You’ll never know unless you try. It was the only asthma medication that’s ever helped me. Good luck

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Thank you! This made me feel a little better about the possibility of using this drug.

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Profile picture for kathleenkapes @kathleenkapes

Thank you! This made me feel a little better about the possibility of using this drug.

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After 2 years of prednisone for PMR, due to the COVID shot, I absolutely cannot deal with more back pain. Also, the side effects from Tezspire of swelling on the face and tongue scare me.
I feel I am being railroaded into taking this by my allergist, and that there are other options to try before an injectable drug that will stay in my body.

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my mom (58, female) was diagnosed with mild asthma last november out of nowhere after a particularly bad sinus infection (never had asthma as a kid). since then, she would occasionally use a rescue inhaler when sick… until July when she got an MRI and the injected contrast sent her into a severe asthma attack that never resolved. it’s been 3 months and she is symptomatic all day everyday with coughing or clearing mucus or chest tightness and shortness of breath. she never leaves the house and has no quality of life.

tried tons of inhalers, most had horrible side effects (including crippling anxiety that she’s never had before) and none of them ever make her breathe well/normal. oral prednisone isn’t even doing much anymore. her CT scans, chest x-rays, and pulmonary function tests have remained the same from November to now (mostly normal, pft only shows mild obstructive disease and mild COPD overlay even though she never smoked) but her everyday symptoms are severe.

doctor is considering biologics (namely Tezspire) but she’s afraid to start due to potential side effects/lack of benefit because she doesn’t have allergic or eosinophilic asthma (it’s “non-type 2”, not allergy or exercise induced. IgE is nonexistent)

anyone with non-allergic, non-eosinophilic asthma have any luck with Tezspire? or anything else at all? we’re desperate. thanks!

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