Completed 5 years of anastrozole. Withdrawal symptoms? Side effects?

If this was me, I'd check in with my primary care doc as all of these symptoms sound like they might also be an unrelated infection--viral or bacterial. That is, if you have a flu-like illness or even an atypical UTI you'd have these symptoms. If you are not additionally ill, the doctor might have advice too if this is the anastrozole. Personally, I have come off my AI for brief "vacations" and never had symptoms. Wishing you the best!

I see my doctors, both my oncologist and gp regularly, so I'm very confident these are withdrawal symptoms. I don't know how long your"vacations" are, but I wish you the best, when you are taken off the anastrozole. It's not fun.

I had no withdrawal symptoms when I went off anastrazole after five years. Just no more severe diahrea. Little hair loss now. With the help,of WW was able to lose weight

Do any of you pink queens know if it is fine to take vital protein collagen peptides daily if your on Anastrozole? I’m estrogen positive. I’ve been taking collagen for years and it helps with hair and nail health. If the blocker is suppose to deplete estrogen totally from the body will this product increase estrogen? Thanks

Kathy- wondering about your switch from anastrozole to Exemestane. I am 1 year in on anastrozole and while I *might( be sleeping a tad better my joints/tendons orthopedic issues are off the chart. Hobbling like an old lady when I get up from sitting/bed/static position and I seem to be falling apart. I am 56 and is (was) very active in gym, HIIT classes, long hiking etc and now just can't tolerate:-(

Did the switch help in that way?

I was on Anastrozole for a year before switching to Exemestane due to finger stiffness. The stiffness is getting a lot better but the joint pain doesn't go away. The achiness of the feet is coming back but not so bad. The joint pain does go away after a few minutes of stretching. I'm still doing my regular exercise (running, swimming etc.) I'm taking turmeric but it doesn't seem to help much. I guess we just have to learn to live with ache and pain until we can't tolerate any longer. I'm 62 and feel like 70! Wish you all the best. Hugs.

Yes - it took a few weeks, like maybe 12 weeks - but the horrible joint pain resolved. On exemestane it was at about a 7 all the time, mostly in my hands, shoulders and toes. My Oncologist made me go to an arthritis doctor to verify it was not that causing the pain. It was not arthritis. It calmed down to about a 1 or 0 after 3 months or so. I understand for some people it does not resolve, but I would then ask your doctor to try another drug. I think there are 5 drugs in total that are in the AI category. The younger people (premenopausal) usually get put on tamoxifen. Honestly I can say if the pain had not gotten considerably better - I'd have gone back & asked for something different. I was 62 when I started on the meds. I read that something like 40% of ladies with severe side effects quit taking the drug before the full 5 years. Good luck to you!

thank you! I will inquire with my MD. Appreciate the info.