Anyone have experience with CAR-T therapy for multiple myeloma?

Posted by claydavis @claydavis, Nov 29, 2025

I was diagnosed with MM in July 2022 at age 53. Did induction on RVD followed by autologous transplant in Dec 2022. Never achieved MRD negative, and have been on Darzalex trial for maintenance. Disease has returned over the past 3-4 months and now contemplating bridging therapy in prep for CAR-T. Still working in fairly high stress occupation and trying to figure out what CAR-T looks like while trying to work. Any insights or counsel from the community? With gratitude…..

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Profile picture for Lori, Volunteer Mentor @loribmt

Good morning @a621030 This was great news for your wife and you…I know as her designated care giver you’re shouldering much of this experience along with her. I’m sure she’ll be happy to have that PICC line out! That gets annoying. Ah, now she can shower without wrapping her arm in plastic. That’s a happy moment right there!
Wishing her continued success with her CAR-T!
Will you keep us updated, please?

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@loribmt even better news. Car-T therapy seems to have been successful! After bone marrow sample was evaluated, nearly “0” myeloma was detected. Last M-Spike was near “0”. All labs looking good, white cells coming back.

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Profile picture for a621030 @a621030

@loribmt even better news. Car-T therapy seems to have been successful! After bone marrow sample was evaluated, nearly “0” myeloma was detected. Last M-Spike was near “0”. All labs looking good, white cells coming back.

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Ohh!! @a621030 This is excellent news! More and more, Car-T Therapy has been showing positive outcomes for people with Multiple Myeloma!! I’m so happy you posted this update. This brings much needed support for others with this blood cancer! A hug to both of you!! (And a happy dance 💃💃 with my two left feet!)

How is your wife feeling now? Energy and stamina levels gaining ground?

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