Risedronate side effects

@humbug Hello! I had muscle and joint pain from Risedronate Sodiaum that was fairly mild but did not realize it was from that until I stopped taking it. I used Evenity for 11 mos initially and after 6-7 months it was quite debilitating with significant muscle, joint, tendon pain. I am active and healthy so it was very different from my “normal”. Immediately following Evenity I took Fosomax and that caused a lot of muscle and joint pain. Switched to Risedronate Sodium for two years and it was manageable but not great. Not on any drugs now for two months and feel so much better. Discomfort was definitely from the drugs. Watching diet and exercise/strenghtening consistently for now. Listen to your body as you know it best.

@lauratys Thanks so much for sharing your experience with Risedronate! Good to know that I am not imagining things. At first I thought my joint pain was due to prednisone withdrawal in February, but according to my blood work nothing appears to be off with cortisol, etc. So, it must be the risedronate. I'm also very active and a runner, so the knee pain is definitely affecting this. Interestingly, I only get pain when bending the knee, like in walking up stairs, standing up, etc. though I also feel it with high impact which was not the case before I started Risedronate. In July, I have a plan, in collaboration with my doctor, to go off Risedronate for three weeks to see if the joint pain improves. It is bilateral, and I also feel it to a lesser extent on my wrists, also bilateral. Glad you are off the drugs and lifestyle approaches are working for you. I'm hoping for the same!

I had issues with my wrists as well. Actually most joints! Hope it resolves for you!

I have had some dizziness since starting the drug. I’ve been on it for 5 months and have just noticed the dizziness in the last month. I’m glad to see others are experiencing it… very unnerving when you walk for 45 minutes each day.

Thanks for your reply

In addition to the leg and ankle weakness and unsteadiness that may or may not be related to an inner problem, I have begun to have pain in my feet. It's like I'm walking on marbles. There is also a very slight tingling. I've purchased new, expensive, tennis shoes, but they haven't helped. My knees also hurt when I kneel on the floor. This is all new to me. I've been on Risedronate for about three months. My next step is to see my doctor as soon as possible and try to go off of this medication. I would like to hear from others who may have had similar problems. I'm also interested in any discussion about any difficulties in going of this med.

@1eileen1
I've been on Risedronate for a few months and also experience weird tingling sensations in my feet and arms. It's very random. And, yes, my feet are also overly sensitive. And my knees hurt when kneeling, getting up, walking up stairs.
In July I'm doing a trial of stopping it for 3 weeks. My doctor and I will know at that point if it's Risedronate and I will stop taking it if all suddenly returns to normal. Hope that helps.

@1eileen1
Thank you for sharing. I’ve had the same experiences with my knee. I also felt weakness in my thigh and hip. I stopped taking it about a month ago and started to feel less and less pain/weakness.
I had X-rays and PT which helped some but not much. Still in slit of pain.

I'm so sorry to hear about your experience with this drug. Mine is not nearly as severe, but it certainly has been bad enough to be concerning. I'll be seeing my osteopetrosis doctor next week and will discuss this with him. The big problem is that all of these bone builders have side effects, and I'm nervous about long term effects. This would be especially true with injections, so I prefer a pill form. Please let me know if you learn more that is helpful.