Reclast Infusions: Side-effects & Recovery time

Posted by cindydee @cindydee, Mar 20, 2018

I just had a reclast infusion last week and have had serious side effects. I had the worst flue like aching for 5 days then my lefty arm became full of inflammation in the wrist, elbow and shoulder which caused extreme pain and I lost the ability to straighten my elbow. Ultrasound showed huge amounts of fluid throughout the arm. The right arm is now starting to have the same symptoms. The pain is excruciating. Has anyone else experienced anything like this? Neither the ER doctor nor the Dr. who prescribed the procedure knew what to do to ease the symptoms. Both arms from fingertips to shoulder are swollen and neither elbow will straighten. Anyone else have adverse reactions to the reclast infusion? If yes, how long did it last?

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@ayetman

I think there are multiple causes of arthritis (joint swelling) after reclast and a swollen knee may be due to CPPD (pseudogout) with a risk of recurrences or may be an inflammatory arthritis without the calcium crystals which is less apt to recur over time. @cccs you may have had the latter.

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Thank you for your comment.
I have had joint aspirations x 3. Each time there were calcium pyrophosphate crystals. There are no calcifications in the cartilage of the joint. The joint effusion is not episodic, just continuous for 6 months.
It is a difficult situation.

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@ang67

Hello, all, I had a Reclast infusion on Dec 18, 2024. I drank a lot of water before and after and took Tylenol and had no real known side effects. However, I quickly put on 10 pounds through the holidays. I have not been able to get this off. Would like to know who else this has happened to. I am only 5 feet tall so every 5 pounds makes a difference and 10 means there are clothes I can’t wear now. I’m so flabby now and the regular exercise I did before doesn’t seem to help. I have a specific diet I follow. Have kidney stones too so there are some foods I can no longer eat. Just wondering if others have had this issue on Reclast and if it ever resolved? Saw my oncologist yesterday and she wasn’t aware of weight gain being an issue. Thank you in advance.

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Yes. Had my infusion in February 2025. Lots of side effects. The weight gain has been terrible. I am only 5’1 and nothing fits. I exercise everyday and get a healthy diet. I have a huge stomach now. Lots of stomach pain. Never again.

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Yes tremendous pain in the ribs
Sharp burning
ER visits, cardiologist, pain management
Two months already and no releif

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