Pulse field ablation

Posted by wews @wews, Nov 25, 2025

Has anyone had a pulse field ablation? I have three precious ablations but none have worked because the place in my heart that the cardiologist needs to ablate is too close to my esophagus. I am scheduled to have one in mid December. He said I have a 60% chance of it working. Does anyone have any experience with this? Has anyone had one? Has it worked? Any insights or downsides are appreciated.

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I personally had PFA in Dec 25 that was a total failure then another in January 26 that one lasted a week. Consulted with Dr. Gerstenfeld at UCSF here's what he says about PFA and pulmonary vein ablation. "We have learned that particular PFA catheter , while it works well for pulmonary veins has a high rate of recurrence when used for linear ablation."

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Profile picture for nevets @nevets

@gloaming

Based on what research I have done, in addition to the benefits you site, PFA involves shorter catheter dwell time and less risk of esophageal damage (a rare but serious complication).

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@nevets True, at least insofar as the research suggests, but that reduced catheter dwell time doesn't translate into improved outcomes....not yet. Maybe they need to rethink the dwell time, in which case there may eventually be no advantage over RF in terms of the risks to the phrenic nerve and to the esophagus, and also to the Vagus nerve (which I didn't mention earlier). We'll see eventually.

I just read a report that PFA also causes an acute reduction in blood pressure but mostly when the left superior PV is ablated with its first one or two applications. The other PVs are not affected, and each subsequent application in circulation around those veins doesn't show any further drop in BP. One center, one set of data, but it bears more scrutiny.

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Profile picture for gloaming @gloaming

@nevets True, at least insofar as the research suggests, but that reduced catheter dwell time doesn't translate into improved outcomes....not yet. Maybe they need to rethink the dwell time, in which case there may eventually be no advantage over RF in terms of the risks to the phrenic nerve and to the esophagus, and also to the Vagus nerve (which I didn't mention earlier). We'll see eventually.

I just read a report that PFA also causes an acute reduction in blood pressure but mostly when the left superior PV is ablated with its first one or two applications. The other PVs are not affected, and each subsequent application in circulation around those veins doesn't show any further drop in BP. One center, one set of data, but it bears more scrutiny.

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@gloaming
Reduced dwell time equals a shorter procedure, which is never a bad thing regardless of the outcome. Of course, new medical technologies are usually viewed as superior from the manufacturer's perspective ($$$) and who knows to what extent they have their thumb on the medical community scales?

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Profile picture for nevets @nevets

@gloaming
Reduced dwell time equals a shorter procedure, which is never a bad thing regardless of the outcome. Of course, new medical technologies are usually viewed as superior from the manufacturer's perspective ($$$) and who knows to what extent they have their thumb on the medical community scales?

Jump to this post

@nevets It may mean a shorter procedure, which may mean less anesthetic, but there's that problem of increased exposure to fluoroscopy. Seems there no magic bullet in the world of catheter ablations. I am optimistic we'll get 'there', hopefully before I need a third ablation. So far, so good....

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