Positive ANA: What might be the cause?

Posted by FreedomWarrior @freedomwarrior, Apr 28 3:51am

Hello,
I am reaching out to anyone who has had a positive ANA blood test result. I aced Rheumatology testing and I believe that Mercury toxicity is the cause. Does anyone have a similar case or know somebody who does..? TY..!

My rheumatologist tested for many things, not sure what all. From what I could discern from the results I did have one high reading which points to a connective tissue disease (which I believe could be SFN or Sjögren’s?) according to my neurologist, but all the rest seemed within range. I understand that often people test negative for Sjögren’s but have many symptoms. I have to wait til July to know more.

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@helennicola

My rheumatologist tested for many things, not sure what all. From what I could discern from the results I did have one high reading which points to a connective tissue disease (which I believe could be SFN or Sjögren’s?) according to my neurologist, but all the rest seemed within range. I understand that often people test negative for Sjögren’s but have many symptoms. I have to wait til July to know more.

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My labs and symptoms sparked some interest at my rheumatology appointment. I’m apparently an “anomaly” and I’m to be a discussion topic at the department meeting this week. So, I’m hopeful I might get somewhere. My symptoms just keep getting worse, so I just hope a solution is found soon.

I just found out that SS can lead to SFN. You may find this informative:
https://www.hopkinssjogrens.org/disease-information/sjogrens-syndrome/neurologic-complications/
Also, I recently discovered this website as well. My symptoms came on rapidly and are mostly neurological, so this information was helpful.
https://www.uptodate.com/contents/sjogrens-syndrome-beyond-the-basics
Best wishes in your search for a diagnosis.

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@helennicola

Hi Freedomwarrior, now you have me worried! How did you determine the toxicity being from sushi? I eat it often and have previously ignored the possibility of it. (stupidly?) Helen

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Hi Helen,
Not knowing is not being stupid.
In my case, I am very toxic with Methylmercury (MM). I was stationed in the Far East and ate tons of raw fish and continued to do so when I returned stateside. My claim is by exclusion of other Mercury sources, although I have read that the human body can convert Elemental Mercury (EM) (Dental Amalgam) in to MM. However, my heavy fish consumption, mostly tuna, lends itself to my test-confirmed MM poisoning. I consumed raw tuna roughly from 1994-present. The body's MM excretion method is via hair.
I am also test-confirmed toxic with Elemental Mercury from Dental Amalgam, again by exclusion. Its excretion method is via the toilet, both inputs.
My first symptom was, since 2013, unending head and ear ringing. Again, by exclusion. I stopped working in a hazardous noise environment in 2013, and I am fervent in protecting my hearing. I was exposed to hazardous noise in the USAF for 15 years daily, and periodically for another 13. Add five more years as a contractor.
My poisoning is SO bad (how bad is it..?), that it is in my skin oil, blood, and saliva.
While searching for an accurate test, I acquired a USB microscope and have microscopic pictures of the Mercury in my skin oil. I have lost tricep, bicep, pectoral, shoulder, and calf muscles. The atrophy is caused by compromised communication between the brain and muscles, akin to Amyotrophic Lateral Sclerosis, or Lou Gherig disease (ALS.org).
To your question, the human body has NO use for Mercury. It is causal in brain disorders like Alzheimer's, Parkinson's, Dementia, and more. The test that I used is called a "Tri-Test" from Quicksilver Scientific (QS) that tests hair (excretion), urine (excretion), and blood (two tests) that differentiate between MM and EM. The site recommends ordering the test through a Functional (Holistic) Medicine provider. Mine marked the kit up by $100. The reason QS wants patients to use a provider is to interpret the test results. My total test cost was $400. For me, testing was IMPERATIVE.
I interpreted my test results before I saw the provider. It is not rocket science, just graphs, but QS' test interpretation instructions are important.
I hope that I answered your questions. Getting tested is an individual choice and I am happy to share my results with you, conditional on not sharing my information. I already redacted a copy, but please do not share my posted picture. Feel free to private message me if you need more information. I have researched Mercury toxicity for the past 3+ years while searching for a good test. Much more to this public health issue than the CDC and FDA will publicly admit. Try https://amalgam.com for more info. Dr. Leo Cashman has been at this for far longer that I, though I will take the fight to another level, maybe via a PhD dissertation. Hit this too, very credible information: (https://orawellness.com/how-to-safely-remove-mercury/).
Take Care,
–> Rick

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@freedomwarrior

Hi Helen,
Not knowing is not being stupid.
In my case, I am very toxic with Methylmercury (MM). I was stationed in the Far East and ate tons of raw fish and continued to do so when I returned stateside. My claim is by exclusion of other Mercury sources, although I have read that the human body can convert Elemental Mercury (EM) (Dental Amalgam) in to MM. However, my heavy fish consumption, mostly tuna, lends itself to my test-confirmed MM poisoning. I consumed raw tuna roughly from 1994-present. The body's MM excretion method is via hair.
I am also test-confirmed toxic with Elemental Mercury from Dental Amalgam, again by exclusion. Its excretion method is via the toilet, both inputs.
My first symptom was, since 2013, unending head and ear ringing. Again, by exclusion. I stopped working in a hazardous noise environment in 2013, and I am fervent in protecting my hearing. I was exposed to hazardous noise in the USAF for 15 years daily, and periodically for another 13. Add five more years as a contractor.
My poisoning is SO bad (how bad is it..?), that it is in my skin oil, blood, and saliva.
While searching for an accurate test, I acquired a USB microscope and have microscopic pictures of the Mercury in my skin oil. I have lost tricep, bicep, pectoral, shoulder, and calf muscles. The atrophy is caused by compromised communication between the brain and muscles, akin to Amyotrophic Lateral Sclerosis, or Lou Gherig disease (ALS.org).
To your question, the human body has NO use for Mercury. It is causal in brain disorders like Alzheimer's, Parkinson's, Dementia, and more. The test that I used is called a "Tri-Test" from Quicksilver Scientific (QS) that tests hair (excretion), urine (excretion), and blood (two tests) that differentiate between MM and EM. The site recommends ordering the test through a Functional (Holistic) Medicine provider. Mine marked the kit up by $100. The reason QS wants patients to use a provider is to interpret the test results. My total test cost was $400. For me, testing was IMPERATIVE.
I interpreted my test results before I saw the provider. It is not rocket science, just graphs, but QS' test interpretation instructions are important.
I hope that I answered your questions. Getting tested is an individual choice and I am happy to share my results with you, conditional on not sharing my information. I already redacted a copy, but please do not share my posted picture. Feel free to private message me if you need more information. I have researched Mercury toxicity for the past 3+ years while searching for a good test. Much more to this public health issue than the CDC and FDA will publicly admit. Try https://amalgam.com for more info. Dr. Leo Cashman has been at this for far longer that I, though I will take the fight to another level, maybe via a PhD dissertation. Hit this too, very credible information: (https://orawellness.com/how-to-safely-remove-mercury/).
Take Care,
–> Rick

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Hi Rick, I am so sorry for your terrible history of mercury poisoning. I hope you are able to find some satisfactory help and closure. I also believe there is so much the public is never made aware of regarding our health industry as everything is predicated on making money today. I wish you the very best going forward. Hugs and prayers, Helen

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Hi there,
Last year I had a positive ana of homogenous and mixed speckled pattern both with a titre of 1:1280. At the time I had a bunch of random symptoms including anemia, hair loss, dizziness, fatigue, fainting, headaches and nausea to name a few, I could barely stand up some days. I have had periods throughout the past 5 years where these symptoms come and go and had many tests but nothing ever eventuated until I had the positive Ana. I saw a rheumatologist who treated me with high dose steroids but my symptoms only 80% went away, he basically said that he doesn’t think it’s autoimmune related and to come back if I ever had symptoms again. My new GP retested my ANA which is now dense fine speckled pattern 1:2560. I am reading a lot of articles that DFS pattern can be clinically insignificant in “healthy individuals”. Can the other patterns go away or not show up if not currently in a ‘flare up’ or can they change? Just looking for some direction on where to go next with this information or weather I should be concerned. I have a few odd symptoms but I am not currently feeling as unwell as I have previously but have a few odd symptoms such as kidney/chest pain. any advice would be much appreciated. Thank you.

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@georgiakate

Hi there,
Last year I had a positive ana of homogenous and mixed speckled pattern both with a titre of 1:1280. At the time I had a bunch of random symptoms including anemia, hair loss, dizziness, fatigue, fainting, headaches and nausea to name a few, I could barely stand up some days. I have had periods throughout the past 5 years where these symptoms come and go and had many tests but nothing ever eventuated until I had the positive Ana. I saw a rheumatologist who treated me with high dose steroids but my symptoms only 80% went away, he basically said that he doesn’t think it’s autoimmune related and to come back if I ever had symptoms again. My new GP retested my ANA which is now dense fine speckled pattern 1:2560. I am reading a lot of articles that DFS pattern can be clinically insignificant in “healthy individuals”. Can the other patterns go away or not show up if not currently in a ‘flare up’ or can they change? Just looking for some direction on where to go next with this information or weather I should be concerned. I have a few odd symptoms but I am not currently feeling as unwell as I have previously but have a few odd symptoms such as kidney/chest pain. any advice would be much appreciated. Thank you.

Jump to this post

Hello @georgiakate Welcome To Mayo Clinic Connect. We are a group of individuals who help each other through health journeys by sharing information and tips and on what has worked for us and what has not. We are not medical professionals so we cannot diagnose or prescribe medication, we can simply prescribe information, resources and tips.
You have seen a rheumatologist who detected a high ANA score but he he does not think that there you have an auto immune disease. You do have lots of vague problems or symptoms but he doesn’t think these are important. Is that correct? Then your GP finds that your ANA score almost doubled.
Can you return to the rheumatologist, tell him that your ANA has doubled, and ask about special lab work for autoimmune diseases?

https://hoagmedicalgroup.com/articles/what-does-a-positive-antinuclear-antibody-mean/. I added this link about some rheumatologists talking about autoimmune diseases.

Will you come back and let me know what you have learned? Becky

REPLY
@georgiakate

Hi there,
Last year I had a positive ana of homogenous and mixed speckled pattern both with a titre of 1:1280. At the time I had a bunch of random symptoms including anemia, hair loss, dizziness, fatigue, fainting, headaches and nausea to name a few, I could barely stand up some days. I have had periods throughout the past 5 years where these symptoms come and go and had many tests but nothing ever eventuated until I had the positive Ana. I saw a rheumatologist who treated me with high dose steroids but my symptoms only 80% went away, he basically said that he doesn’t think it’s autoimmune related and to come back if I ever had symptoms again. My new GP retested my ANA which is now dense fine speckled pattern 1:2560. I am reading a lot of articles that DFS pattern can be clinically insignificant in “healthy individuals”. Can the other patterns go away or not show up if not currently in a ‘flare up’ or can they change? Just looking for some direction on where to go next with this information or weather I should be concerned. I have a few odd symptoms but I am not currently feeling as unwell as I have previously but have a few odd symptoms such as kidney/chest pain. any advice would be much appreciated. Thank you.

Jump to this post

@georgiakate, I add my welcome to Becky's. You'll notice that I moved your message to this existing discussion on the same topic. I encourage you review the past posts and connect with members. You may also be interested in this older discussion with great info and support:
– What can cause ANA titre of 1:2560? https://connect.mayoclinic.org/discussion/what-can-cause-ana-titre-of-12560/

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@becsbuddy

Hello @georgiakate Welcome To Mayo Clinic Connect. We are a group of individuals who help each other through health journeys by sharing information and tips and on what has worked for us and what has not. We are not medical professionals so we cannot diagnose or prescribe medication, we can simply prescribe information, resources and tips.
You have seen a rheumatologist who detected a high ANA score but he he does not think that there you have an auto immune disease. You do have lots of vague problems or symptoms but he doesn’t think these are important. Is that correct? Then your GP finds that your ANA score almost doubled.
Can you return to the rheumatologist, tell him that your ANA has doubled, and ask about special lab work for autoimmune diseases?

https://hoagmedicalgroup.com/articles/what-does-a-positive-antinuclear-antibody-mean/. I added this link about some rheumatologists talking about autoimmune diseases.

Will you come back and let me know what you have learned? Becky

Jump to this post

Thank you Becky! that sounds about right. I understand my symptoms are quite vague and from reading auto immune related diagnosis can be quite difficult. I am booked into see a new rheumatologist as I have since moved but that’s not until late august so have just been doing my own research in the meantime. I will have a browse of the link and previous posts to see if I can find anything useful! My main question was can the pattern change if I have had homogenous and speckled in the Past and now it is dense fine speckled is that significant in anyway? I will definitely keep you updated. Thanks again

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@colleenyoung

@georgiakate, I add my welcome to Becky's. You'll notice that I moved your message to this existing discussion on the same topic. I encourage you review the past posts and connect with members. You may also be interested in this older discussion with great info and support:
– What can cause ANA titre of 1:2560? https://connect.mayoclinic.org/discussion/what-can-cause-ana-titre-of-12560/

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Thank you Colleen. I have read that post aswell. ☺️

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My ANA is elevated. Not terribly high, but enough to be a little+- worrisome. Most of the sources I have found, including places around the world (U of Helsinki, etc.), use an increased ANA as the jump-off to look for things like the myeloma family of issues, such as Amyloidosis, Gelsolin, LECT2. Other targets are congenital limb girdle muscular dystrophy, etc. Not saying you have one of these, but it is worth looking at. Have you had Ambry Genetics have a look at your genome? They are very good, and part of it is free.

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@oldkarl

My ANA is elevated. Not terribly high, but enough to be a little+- worrisome. Most of the sources I have found, including places around the world (U of Helsinki, etc.), use an increased ANA as the jump-off to look for things like the myeloma family of issues, such as Amyloidosis, Gelsolin, LECT2. Other targets are congenital limb girdle muscular dystrophy, etc. Not saying you have one of these, but it is worth looking at. Have you had Ambry Genetics have a look at your genome? They are very good, and part of it is free.

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My MCTD has elevated ANA, as well as other diagnostic elements. You may not have a "full blown" issue that is enough for diagnosis, but you can do some things now. One is to go on a non-processed diet, avoid sugar and moderate inflammatory foods like potato, tomato, dairy, wheat. Lifestyle-wise, get in that daily walk, work on simplifying life so you are not as stressed, eliminate fragrance from household, etc. I liked Dr A Weil's book 8 Weeks to Optimum Health, as a beginning. Perhaps you will not progress to a disease that can be identified. Be careful about reading into the internet info: stick to webmd, mayo or cleveland clinic sites.

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@becsbuddy

Hello @georgiakate Welcome To Mayo Clinic Connect. We are a group of individuals who help each other through health journeys by sharing information and tips and on what has worked for us and what has not. We are not medical professionals so we cannot diagnose or prescribe medication, we can simply prescribe information, resources and tips.
You have seen a rheumatologist who detected a high ANA score but he he does not think that there you have an auto immune disease. You do have lots of vague problems or symptoms but he doesn’t think these are important. Is that correct? Then your GP finds that your ANA score almost doubled.
Can you return to the rheumatologist, tell him that your ANA has doubled, and ask about special lab work for autoimmune diseases?

https://hoagmedicalgroup.com/articles/what-does-a-positive-antinuclear-antibody-mean/. I added this link about some rheumatologists talking about autoimmune diseases.

Will you come back and let me know what you have learned? Becky

Jump to this post

Thanks, Becky. This is helpful.

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