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platinum-resistant ovarian cancer, treatment options
Hi, My wife was diagnosed with Stage IV High Grade Serous Ovarian Cancer in May 2024. After debulking and 7 chemotherapy sessions she had her cancer in remission in Jan 2025. First follow-up tests, CT Scan and bloodwork, CA-125 at 70 in April 2025 indicates the cancer has reoccurred. We see the GYN Oncologist tomorrow. Has anyone had any experience with platinum resistant cancer recently had new therapy drugs or clinic trails in SW Michigan to fight the reoccurrence? I’m trying to find best treatment options for my wife. Thank you.
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When is OC considered platinum resistant? I finished six treatments for Stage 3b at the beginning of August 2024 and so far things are okay but it’s just 8 months. Next labs are in May and I’m starting to get quietly freaked out….
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3 Reactions@amywells
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/platinum-sensitive-cancer
what do you mean by things are ok? You feel ok? Has the tumormaker CA125 been checked, since you finished treatment?
Are you getting immunotherapy, are you scheduled for a CT scan? There are many success stories of people who
live with OC stage 3 or higher. May is around the corner,
try to do something that gives you joy. My next CT scan is also in early May, I feel nervous about it like many of us in the same situation. The first two CT scans after finishing
6 cycles of Chemo did not show any disease. My tumor marker stayed low and the same. My cancer is also stage 3b.
Can you share your results? Wishing you good news.
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2 ReactionsThank you for your encouragement Charlotte! I have labs checked every three months and so far everything has looked good...CA125 stable in the teens. If it stays stable I'll have CT scans in August. They did not put me on immunotherapy at this time and I'm not a candidate for a PARP inhibitor. I feel well and am living a full life at 73 with plenty of joyful times....but also, as we all know, with the possibility of recurrence hanging somewhere around my head at all time. Sometimes it's way behind me and sometimes it's right in the forefront, esp as the next lab check approaches.
When did you receive your diagnosis? And are you on immunotherapy? Sounds like you have CT scans more frequently than I do...
I wish you good news too!
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1 ReactionPlatinum Resistant Ovarian Cancer (PROC) means the cancer cells have become resistant to treatment with platinum based drugs like carboplatin or cisplatin (commonly used for 1st line of treatment), the resistance is typically defined as cancer recurrence within “six months” of completing platinum based chemotherapy. If it has been longer than six months with no cancer recurrence you are considered platinum sensitive.
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