New Predictive Blood Test: ctDNA

Posted by colely @colely, Jun 10 8:37am

From http://www.theguardian.com. A new ctDNA blood test identifies returning circulating tumor cells before a scan can find cancer recurrence. The old ctDNA used a technique called whole exome sequencing that typically looks for between 16 and 50 mutations. The new test uses whole genome sequencing and searches for 1,800 mutations making it more sensitive. June 2, 2024. This sounds like a real advancement! I wonder when it will be implemented in our treatment.

Interested in more discussions like this? Go to the Breast Cancer Support Group.

elizabet | @elizabet | 6 days ago

In reply to @bjohnson511 "Can this test identify future breast cancer percentages?" + (show)

My oncologist said that "negative" is the hoped for result, however if it comes back "positive", a number is always attached, which (I am only guessing) might be the percentages you're asking about. The Natera website is a very informative resource. https://www.natera.com/oncology/signatera-advanced-cancer-detection/clinicians/signatera-for-breast-cancer/

kstar077 | @kstar077 | 6 days ago

In reply to @elizabet "My predictive blood test is called Signatera." + (show)

Is signatera blood test show microscopic cancer?

kstar077 | @kstar077 | 6 days ago

In reply to @elizabet "My predictive blood test is called Signatera." + (show)

Thank you...I will forward to my oncologist to order.

katie5515 | @katie5515 | 6 days ago

In reply to @kstar077 "Insurance does not pay for new blood test. My oncologist said so." + (show)

Call Natera and speak to them directly. Ask them about your specific insurance and out of pocket costs.

kstar077 | @kstar077 | 6 days ago

In reply to @katie5515 "Call Natera and speak to them directly. Ask them about your specific insurance and out of..." + (show)

Will call. Thx

colely | @colely | 5 days ago

In reply to @kstar077 "What exactly is the blood test called? I am on Medicare and I had breast cancer...." + (show)

I went and re- read my post. I don't think it has a name, yet. If it is being done in trials in U.S. hospitals, I assume they would be the top breast cancer clinics, which eliminates mine. From what I've read, it absolutely will be coming. Good predictive abilities seems crucial to saving our lives!

elizabet | @elizabet | 4 days ago

In reply to @colely "I went and re- read my post. I don't think it has a name, yet. If..." + (show)

I think you are describing Signatera. At the bottom of the Natera website is a place where your doctor can request more information. https://www.natera.com/info/personalized-mrd-test/

anjalima | @anjalima | 4 days ago

In reply to @colely "I went and re- read my post. I don't think it has a name, yet. If..." + (show)

Signatera is the test, ct DNA ( circulating tumor DNA) is what is being measured ( hopefully negative) and identified by analysis of your biopsied or surgically removed tumor tissue. Natera is the company.

colely | @colely | 2 days ago

In reply to @elizabet "I think you are describing Signatera. At the bottom of the Natera website is a place..." + (show)

Sorry, but this is not Signatera. It is new, much better test. Please see my June 10th post. Signatera uses whole exome, new test uses whole genome. Looks as if test is not on market, yet. By all means get Signatera, now, but look forward to new hope with this new test.