NASH and cirrhosis of the liver.

Posted by mollyb1968 @mollyb1968, Sep 1, 2016

I have type 2 diabetes and have been diagnosed with chronic non-alcoholic steatohepatitis with mild intracytoplasmic cholestasis. Minimal lobular actvity. Scattered lymphocytic infiltrates noted within the portal tracts with minimal hepatocyte necorsis and mild portal fibrosis. Due to also having portal hypertension, gastric varices and stomach polyps, it has been suggested that I may have cirrhosis of the liver as well. Does anyone else have this diagnosis and should I be greatly concerned? Is there treatment for this? Any help would be appreciated.

@mollyb1968

Hi Rosemary, I haven’t talked with you for a while and I am not sure how to get to your page. I posted a while back that my doctor said I was stage 4 fibrosis, which is cirrhosis. However, she told me last month that I was stage 4 cirrhosis but my liver was compensated. I am scheduled for another EGD on March 16th. My tests are all running the same so what makes it change to stage 4 cirrhosis instead of, maybe, stage 1 cirrhosis. She said there were a number of factors such as portal hypertension and gastric varices. Does this make sense and am I understanding correctly. Thank you in advance for your help.

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Hi @mollyb1968, thanks for this post! I was thinking about you last week, and I never got around to posting it to you.
It looks like you are getting some good continuing care by your doctor. All this stuff, makes sense, to me only because it is all so interconnected with the liver. I assume that you are currently taking meds to keep portal hypertension in check. The EGD will give the medical team a clear picture if these meds are doing their job well enough. The varices are related to the hypertension which is related to liver and cirrhosis. I’ve had EGD to look for esophageal varices, and later had one to repair the bleeding varices. You can take comfort knowing that your doctor is monitoring this in order to prevent a potentially serious complication.
I continue to encourage you to take your list of questions to your doctor. And to ask for an explanation in everyday – nonmedical language. I have also found it helps me to repeat it back to my doctor to be sure I understand correctly.
Molly, how are you feeling these days?
Rosemary
PS I’ll be thinking of you on Mar. 16. Let me know how it goes.

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@mollyb1968

Hi Rosemary, I haven’t talked with you for a while and I am not sure how to get to your page. I posted a while back that my doctor said I was stage 4 fibrosis, which is cirrhosis. However, she told me last month that I was stage 4 cirrhosis but my liver was compensated. I am scheduled for another EGD on March 16th. My tests are all running the same so what makes it change to stage 4 cirrhosis instead of, maybe, stage 1 cirrhosis. She said there were a number of factors such as portal hypertension and gastric varices. Does this make sense and am I understanding correctly. Thank you in advance for your help.

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Thank you so much for your encouragement. It helps me feel more sane. I stay very tired and weak. Sugars have been dropping quite a bit lately and we are working on that. Otherwise, not too bad. I hope you are well and I will keep you posted on the EGD. Again, thank you for your encouragement. MollyB1968

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@mariah1203

Biopsy shows cirrhosis stage 4, US shows hepatosplenomegaly, liver measure 29 cm and spleen 15 cm, and portal hypertension at 1.2 Last Meld score was an 11. Not on list, want to be. The doctors where i live have no idea what caused this. I need help.

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I was diagnosed with Primary Biliary Cirrhosis my bile ducts are closing therefore causing Cirrhosis, But have Horrible pain in Pancreas seems during an EUS the students were working on me where they pushed a stone from gall bladder in my pancreas for 5 years so unlike you young lady I can not get a liver transplant, I have no support system I do not test any more seen all NYC best docs no treatment no nothing none of Docs will call me back out of fear of malpractice, God bless you ! Hope you can get a liver transplant !

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@mariah1203

Biopsy shows cirrhosis stage 4, US shows hepatosplenomegaly, liver measure 29 cm and spleen 15 cm, and portal hypertension at 1.2 Last Meld score was an 11. Not on list, want to be. The doctors where i live have no idea what caused this. I need help.

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I know all the test you are referring too. I went to med school but did not finish because broke my leg! I found the site lacked knowledge also,You are to young any talk about transplant? Hope so they gave me 10 years to live 8 years ago?But I am 54 now! PBS is similar to Nash God Bless you D

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@mollyb1968

Hi Rosemary, I haven’t talked with you for a while and I am not sure how to get to your page. I posted a while back that my doctor said I was stage 4 fibrosis, which is cirrhosis. However, she told me last month that I was stage 4 cirrhosis but my liver was compensated. I am scheduled for another EGD on March 16th. My tests are all running the same so what makes it change to stage 4 cirrhosis instead of, maybe, stage 1 cirrhosis. She said there were a number of factors such as portal hypertension and gastric varices. Does this make sense and am I understanding correctly. Thank you in advance for your help.

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Have you had a fibro scan it’s more accurate than liver biopsy because simple fact it can attack different parts of liver ! No infection!!

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@sharonryanbless

Can anyone tell me more about this disease and what happens exactly@

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I also have factor 2 mutation with Lyme diease and I couldn't do anything new without Dr.authorization thanks for your kindness

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Hi I'm Sharon I have 3 1 rare blood clotting disorder and was just told this month I have Lyme disease and now Nash. I have felt with the blood disorder the best I can but now Nash I'm numb I have no one who I can talk to a lot blood disorder and this mad thing I was having depression but noe it seems like I feel nothing how can someone cope with so much and feel human

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@sharonryanbless

Hi I'm Sharon I have 3 1 rare blood clotting disorder and was just told this month I have Lyme disease and now Nash. I have felt with the blood disorder the best I can but now Nash I'm numb I have no one who I can talk to a lot blood disorder and this mad thing I was having depression but noe it seems like I feel nothing how can someone cope with so much and feel human

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Help @sharonryanbless,

You may notice that I moved your messages and combined them with this existing discussion on NASH or nonalcoholic steatohepatitis. I did this as I thought it would be beneficial for you to be introduced to the members who have discussed much of what you are experiencing.
If you click on VIEW & REPLY in your email notification, you will see the whole discussion and can join in, meet, and participate with other members talking about their or their loved ones’ experiences.

I’d like to introduce you to @happyat76 @nina9 @rosemarya @contentandwell who might be able to offer their insights.

I also want to share the following links where you can learn more about non-alcoholic fatty liver disease:
– NASH Patients: Add These Foods to Your Diet https://connect.mayoclinic.org/page/transplant/newsfeed/nash-patients-add-these-foods-to-your-diet/
– NASH Patients: Blog Round-Up https://connect.mayoclinic.org/page/transplant/newsfeed/nash-patients-blog-round-up/
– Five Habits to Adopt if You Have NASH https://connect.mayoclinic.org/page/transplant/newsfeed/five-habits-to-adopt-if-you-have-nash/

Has your doctor offered a treatment plan or next steps, @sharonryanbless?

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Can anyone tell me more about this disease and what happens exactly@

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@sharonryanbless

Can anyone tell me more about this disease and what happens exactly@

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NASH is caused by fat accumulating in the liver, damaging tissue. There are multiple stages of NASH. If it progresses, the end/worst stage is cirrhosis, which is scarring of the liver. If it continues to progress, it leads to liver failure. The good news is that the liver has the potential to repair itself prior to cirrhosis. I'm a relatively new liver transplant recipient. I did not have NASH, as my cirrhosis was caused by alcohol. But in my case as well as yours, the physiological culprit is fat in the liver. I've learned quite a bit about liver health over the past few years, as I'm extremely interested in keeping my new liver in good shape. If you're interested in what you can do slow, stop or reverse the progression of your disease, I'd be more than happy to share my opinions.

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@mickj

NASH is caused by fat accumulating in the liver, damaging tissue. There are multiple stages of NASH. If it progresses, the end/worst stage is cirrhosis, which is scarring of the liver. If it continues to progress, it leads to liver failure. The good news is that the liver has the potential to repair itself prior to cirrhosis. I'm a relatively new liver transplant recipient. I did not have NASH, as my cirrhosis was caused by alcohol. But in my case as well as yours, the physiological culprit is fat in the liver. I've learned quite a bit about liver health over the past few years, as I'm extremely interested in keeping my new liver in good shape. If you're interested in what you can do slow, stop or reverse the progression of your disease, I'd be more than happy to share my opinions.

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Thank you and please I'm not a candor for a liver transplant because of my rare clotting disorder my untrasound has not came back but my blood work showed it was positive when I went back one enzyme dropped but another got higher on top of this I was diagnosed with Lyme disease my clotting disorder attacks my liver that's were they found the fatty liver stenosis but I controlled my enzymes by my weight up tell now I'm overwhelmed thank u I'm open for any information and help understanding all this

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@sharonryanbless

Hi I'm Sharon I have 3 1 rare blood clotting disorder and was just told this month I have Lyme disease and now Nash. I have felt with the blood disorder the best I can but now Nash I'm numb I have no one who I can talk to a lot blood disorder and this mad thing I was having depression but noe it seems like I feel nothing how can someone cope with so much and feel human

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@mollyb1968, I realize that it has been a while since you posted, but I want to invite you to take a look at this new post by @sharonryanbless. Does any of this sound familiar to you? Is there anything that you might be able to share from your own experience.
Rosemary

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@sharonryanbless

Can anyone tell me more about this disease and what happens exactly@

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sharon, Here is information from Mayo Clinic's Patient Care & Health Information
Diseases & Conditions – Nonalcoholic fatty liver disease
https://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/symptoms-causes/syc-20354567
I think this will help you to gather some information as you move forward. What have your doctors said so far?

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@rosemarya

sharon, Here is information from Mayo Clinic's Patient Care & Health Information
Diseases & Conditions – Nonalcoholic fatty liver disease
https://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/symptoms-causes/syc-20354567
I think this will help you to gather some information as you move forward. What have your doctors said so far?

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Thank you I have just excepted I'm a walking time bomb that there was very little info.on my blood disorder hardly none I searched. 8 months and still didn't get much because there isn't any then in the last month I was diagnosed with Lyme diseases and my liver enzymes went out and they told me I had this Nash I'm not a candidate for a liver transplant if it gets that bad.but its been almost. A month and haven't heard anything about ultra sound when I went back one enzyme was higher and other was lower I really appreciate everyone thank u

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@rosemarya

sharon, Here is information from Mayo Clinic's Patient Care & Health Information
Diseases & Conditions – Nonalcoholic fatty liver disease
https://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/symptoms-causes/syc-20354567
I think this will help you to gather some information as you move forward. What have your doctors said so far?

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I just have what I read on google

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