I have been on the Big 3 for 10 months, and have been having increasing gastrointestinal issues and more weight loss (after 4 stable months). As well, I continue to have cultures positive for MAC. Sensitivity testing still says the Big 3 should be working.
Color me frustrated…. Referred to the Infectious Disease doc for the first time.
He suggested a change from clarithromycin to azithromaycin to see if I tolerate it better. And indicated he sees the treatment regimen continuing for up to another year.
Has anyone else had this change to the …mycin, and did it help gastro symptoms and/or weight loss?
What other avenues are available to step up the effectiveness of the protocol?
We are repeating the CT to see if the lungs have improved. I feel like I'm just "maintaining" as far as cough, sputum, energy… My weight is nearing 100lb, and I cannot afford to lose any more as I already feel like I'm nearly a skeleton – ribs and pelvic bones visible, facial bones prominent & skin loose…