Low dose naltrexone for Post-Covid Recovery experiences?

Posted by radapanich @radapanich, May 15, 2023

Does anyone have experiences with low dose naltrexone for long Covid symptoms of significant brain fog, post-exertional fatigue, joint pain, muscle pain - inflammation, insomnia. A few studies in late 2022 indicate that low dose naltrexone 4.5 mg is helpful . Do you know of a specific doctor in NYC who prescribes it?

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@kemmeries

LDN saved my wife's life

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Can you offer more details, such as her LDN dosage and what symptoms improved?

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@radapanich

I have been on low dose naltrexone ie 4.5 mg daily for 8 weeks, combine with NAD (a supplement( as per protocol at Mayo climic). It has helped me significantly. My first prescription was from Mayo pharmacy, subsequent refills from a local compounding pharmacy.

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Can you provide some info on what symptoms improved?

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@prancer20

Has anyone tried low dose Naltrexone or CQ10?
The Long Covid Clinic at Scripps has not been very helpful, with the exception of the physical therapists. I am desperately trying to crawl out of this syndrome . I start feeling better then increase my activity and that is followed by fatigue. I will start the low histamine diet and see how that goes.

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Yes, low dose Methylene Blue is interesting also.

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@prancer20

Has anyone tried low dose Naltrexone or CQ10?
The Long Covid Clinic at Scripps has not been very helpful, with the exception of the physical therapists. I am desperately trying to crawl out of this syndrome . I start feeling better then increase my activity and that is followed by fatigue. I will start the low histamine diet and see how that goes.

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I have been on LDN for Long Covid as post viral anti inflammatory. It is compounded at a well known pharmacy with high standards on preparation and cleanliness. So far I have not seen any improvement in my pain and I too developed burning in my arms. I am going to try to stick with the LDN though to see if it helps the bigger picture or until I cannot take the burning in my arms anymore. I have only been on the 4.5 mg dose since July 7th, 2023 and have had long covid issues since Oct 2022.

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@bebold

I take LDN but have for years. Its a long term decision to make. You don't so much "try it." You kind of decide to do it for years or its not really worth trying. I hear people say they tried it for a month or 2 "and it didn't work." (They were also taking too high a dose. The smaller dose the better. Usually between 2.5 and 4 mg. You have to understand how it works and commit or not.

You kind of wont know if its helping for a year or more. I had objective data in that the amount of synthroid I needed went way down.

I'm alsk very leary of generic medz and naltrexone no longer comes brand name. Pharmacies are starting to sell it but you have to make sure they kniw how to make it including where do they source their powder and most likely, as with all generics, they use whatever is cheapest that month. But is it hard or coldpressed?

There used to be a great yahoo group expert consumers. I studied it for a year before going on it. I get the pill from an American lab (there is only one I think), smash it and mix it with 50ml of distilled water. 50mg in 50 mls equals one mg per ml and I take 4ml (equal to 4mg.) You must work yourself up very very slowly or you may experience side effects and quit I spent 2 months getting tp 3mg/night and stopped there for a couple if years.

Its a very very good antiinflammatory and I have lots of inflammation? Skip, a very knowledgeable pharmacist in S FL who supplies pills all over the US where he can, not NC last I heard, is great. He and his whole family, including teens take it aa it resets (supposedly) your immune system. Its more accepted now than it waa when I started taking it 5 years ago.

I went off for a few months after xmas this year and my thyroid went to uncontrollable again (hashimotos) and back on ldn, its still raking months months to get regulated again. And I didn't know it waa helping pain as much as it does, until I went off.

Ill never go off again. Mixing it myself, it costa me about $12 every year+. I'm a nurse and not all doctors will ler you mix it yourself. If yours will, I can give you more info on how I do it. Store in fridge etc.

Its a long term decision. If yoy aren't in it committed for at least a year or 2, don't bother.

As a nurse, I studied it for a year before making a decision. About 6 years ago maybe? I've gone off a couple of times and have always regretted it as you need to starr low again and it can take months to get back up to speed. Its 7 months since I went back on and I haven't gotten my thyroid back to normal yet. Good luck.

I'm a lifer. You kind if gave to decide to be one too. Taking it is a long term commitment. I've written lots about it here. There a tons of YT videos now by mds that there wasn't when I started.

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Recently recommended I try this as well-I would greatly appreciate your pharmacy contact and measurements, please! As a fellow nurse, I am SUPER particular about my med quality and sourcing! Thank you for sharing your knowledge/experience!

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@prancer20

Has anyone tried low dose Naltrexone or CQ10?
The Long Covid Clinic at Scripps has not been very helpful, with the exception of the physical therapists. I am desperately trying to crawl out of this syndrome . I start feeling better then increase my activity and that is followed by fatigue. I will start the low histamine diet and see how that goes.

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I am trying LDN. I started at 1.5 and then 3.0 for a few months with no noticeable improvement. I do have to take it in the morning to avoid insomnia. I have just recently started 4.5 and am seriously reconsidering it. I find myself taking deep breaths (anxious) and my sleep is horrible, not to mention daily headaches. I know it can take time but not sure it’s worth the trial period. I also take the gummy Coq10, no noticeable difference in my LHC symptoms.

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@javasenora

I am trying LDN. I started at 1.5 and then 3.0 for a few months with no noticeable improvement. I do have to take it in the morning to avoid insomnia. I have just recently started 4.5 and am seriously reconsidering it. I find myself taking deep breaths (anxious) and my sleep is horrible, not to mention daily headaches. I know it can take time but not sure it’s worth the trial period. I also take the gummy Coq10, no noticeable difference in my LHC symptoms.

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Did you ever experience insomnia when taking it in the morning? I recently started taking it, .25mg for a week and now I'm on my 4th day at .5mg. The past 3 nights I've had more trouble sleeping than usual. Maybe it's a coincidence since I had insomnia issues before taking LDN. Just wondered what your experience was?

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@prancer20

Has anyone tried low dose Naltrexone or CQ10?
The Long Covid Clinic at Scripps has not been very helpful, with the exception of the physical therapists. I am desperately trying to crawl out of this syndrome . I start feeling better then increase my activity and that is followed by fatigue. I will start the low histamine diet and see how that goes.

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LDN saves my wife's life.
She was in a bad downward spiral to the point of being bed bound. The very next day after her first dose of 1.5mg she walked into the living room!!!!!!
However she is still very sick. Extreme fatigue, tremors and brain fog amongst many other issues
(We are not a Mayo patient, they have not expected us)

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@ripley

Did you ever experience insomnia when taking it in the morning? I recently started taking it, .25mg for a week and now I'm on my 4th day at .5mg. The past 3 nights I've had more trouble sleeping than usual. Maybe it's a coincidence since I had insomnia issues before taking LDN. Just wondered what your experience was?

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I had insomnia occasionally before LDN, but this is more persistent, it was not as severe last night so I’m hopeful that I can get used to the higher dose. I also find that I have stranger dreams. I had to titrate slowly.

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@prancer20

Has anyone tried low dose Naltrexone or CQ10?
The Long Covid Clinic at Scripps has not been very helpful, with the exception of the physical therapists. I am desperately trying to crawl out of this syndrome . I start feeling better then increase my activity and that is followed by fatigue. I will start the low histamine diet and see how that goes.

Jump to this post

I had significant improvement relatively quickly. I went through Ageless rx. I gained a significant amount of energy and cognition. I would say definitely try it. I also typically experience bad side affects but I haven’t on ldn naltrexone.

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