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Libtayo (cemiplimab) treatment for SCC...any comments?

Posted by Sue, Volunteer Mentor @sepdvm, Dec 16, 2020

I am looking at Cimiplimab, an immunotherapy for metastatic SCC skin cancer and wondering if any others are undergoing this treatment, side effects, success, etc.

Interested in more discussions like this? Go to the Melanoma & Skin Cancer Support Group.

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louisejewell | @louisejewell | Apr 28 12:03pm
In reply to @grammato3 "@louisejewell Let me see if I'm understanding you correctly: the Signatera value (which is a lab..." + (show)
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@louisejewell Let me see if I'm understanding you correctly: the Signatera value (which is a lab test some providers use in conjunction with other tests as an early marker of metastasis) had risen just before imaging showed possible mets in your chest? But before switching to cetuximab - a stronger chemotherapeutic agent - everything returned to normal range and you've not had any further squamous cell lesions; is that correct?

That's great that you can proceed with increased dosage and less commuting. Keep us posted on how the surveillance goes from here out!

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@grammato3 Yes. The signatera jumped from 10 to 30. At that time I had a PET that showed something in my lung. I continued my Libtayo and 2 months later Signatera dropped to 1.7 and new PET showed nothing. My next Libtayo is May 12 and they will do a Signatera test then. I'm just hoping to stay on the 6 week schedule.

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Susan, Volunteer Mentor | @grammato3 | Apr 28 12:49pm
In reply to @louisejewell "@grammato3 Yes. The signatera jumped from 10 to 30. At that time I had a PET..." + (show)
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@grammato3 Yes. The signatera jumped from 10 to 30. At that time I had a PET that showed something in my lung. I continued my Libtayo and 2 months later Signatera dropped to 1.7 and new PET showed nothing. My next Libtayo is May 12 and they will do a Signatera test then. I'm just hoping to stay on the 6 week schedule.

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@louisejewell That's great that it's working so well! Let me know what your next test reveals.

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