Low Dose Naltrexone and Prednisone for PMR?

Posted by pkalkstein @pkalkstein, Mar 1, 2023

My doctor has prescribed LDN and I will be receiving it soon from a compounding pharmacy. I am tapering prednisone, now at 12.5 (from 20 over 4 months) with no pain, although I can feel that PMR is still active. From what I have read, I plan to take 1.25mg of LDN at night, and 10 mg prednisone in the morning, slowly working the LDN up to 4.5 and the prednisone down as reasonably quickly as I can without a flare. Has anyone tried a similar formula? Any advice would be welcome, and of course I will report developments.

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kjoed53 | @kjoed53 | 5 hours ago

My apologies if I've already posted here...
I started at 3mg LDN a little over two months ago to help with my prednisone tapering which became more urgent when I was diagnosed with SMM in May. I've tapered from 25mg to 4.5mg in three months and started kevzara 12 days ago. I think the LDN at night has helped me sleep and lessened the returning pain enough for me to do the fast taper. I'll be increasing to 4.5mg LDN at next refill.