Iron Depletion in Blood related to COVID?

Posted by stellm @stellm, Jun 11, 2021

Has there been any reports of iron depletion in the blood after receiving the Pfizer vaccine?

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@fcast1334

Get her to a Hematologist. They will be the best to treat the low iron. I have had two infusions of iron so far. Had the second one 1 week ago. Feeling fairly good right now. Have to do another blood test the end of April and hopefully the iron level will be close to normal. I saw where one person on here said they were scheduled to have 5 infusions. My infusion is called Infed.

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Thank you for the info!

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I had both covid injections in January and February 2021. In May 2021 I was diagnosed with low hemoglobin count and told to take prenatal vitamins . I took these vitamins through October 2021. At the time. my numbers were so low that I was immediately given iron infusions for six weeks. After these infusions, I was tested 4 weeks later and the numbers were again low. I had another 6 infusions. During the interim, I had endoscopy and colonoscopy and the pill camera for lower intestine. I had a liver sonagram and countless blood tests. The hemotologist stated that My tests did not look like leukemia. Now after all the infusions, I am told that they will give me a stronger iron infusion for the next two weeks.
I am stumped and just wondered if there was a correlation because I never had a problem with my blood. I took the booster in September and am worried about taking the second booster when it is approved. I am a fairly healthy 76 year old with moderate high blood pressure and diabetes which is well controlled with A1C below 6. Thank you for any answers you can provide.

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The tests were negative.

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@steveark

This is very interesting as I am also dealing with iron-deficiency anemia after my Moderna vaccines. In March 2021, I received my second Moderna vaccine. (In August '20, my CBC was normal for all parameters). Few months after my second vaccine I began feeling winded on minor exertion. Blood test indicated low HGB and iron (and very low ferritin). All other lab tests were normal. Upper and lower endoscopy showed no problems. Now seeing hematologist and receiving iron infusions. Waiting to see if iron levels will remain steady or drop back to low levels.

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I thought I would give a little more information about my situation. Prior to my COVID vaccine, I enjoyed excellent health and had never suffered from anemia. After the vaccine, my stamina decreased significantly and my heart labored during light exercise. My cardiologist detected the anemia. Before iron tablets and now iron infusions, my iron level was 27 (normal 49-181 ug/ml) and my ferritin was 5.03 (normal 17.9-464 ng/ml). My HCT, MCV, and MCH levels were all low, as expected. After tablets (for three weeks) low blood levels increased some but most were still below normal. Doctor put me on Venofer infusions (5 infusions). Arkansas Blue Cross would not pay for Injectafer (which is 2 infusions). Again just waiting to see if levels will stay normal after completion of the treatments.

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@jherrin

I had both covid injections in January and February 2021. In May 2021 I was diagnosed with low hemoglobin count and told to take prenatal vitamins . I took these vitamins through October 2021. At the time. my numbers were so low that I was immediately given iron infusions for six weeks. After these infusions, I was tested 4 weeks later and the numbers were again low. I had another 6 infusions. During the interim, I had endoscopy and colonoscopy and the pill camera for lower intestine. I had a liver sonagram and countless blood tests. The hemotologist stated that My tests did not look like leukemia. Now after all the infusions, I am told that they will give me a stronger iron infusion for the next two weeks.
I am stumped and just wondered if there was a correlation because I never had a problem with my blood. I took the booster in September and am worried about taking the second booster when it is approved. I am a fairly healthy 76 year old with moderate high blood pressure and diabetes which is well controlled with A1C below 6. Thank you for any answers you can provide.

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My situation sounds similar to yours, just recently found out I was anemic, never had any problem with anemia in my life. Going through all the tests now to see if they can find a cause and just started iron supplements. Had vaccine dose 2 in June 2021 and developed tinnitus within 10 days, had booster dose in December 2021.

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@jherrin

I had both covid injections in January and February 2021. In May 2021 I was diagnosed with low hemoglobin count and told to take prenatal vitamins . I took these vitamins through October 2021. At the time. my numbers were so low that I was immediately given iron infusions for six weeks. After these infusions, I was tested 4 weeks later and the numbers were again low. I had another 6 infusions. During the interim, I had endoscopy and colonoscopy and the pill camera for lower intestine. I had a liver sonagram and countless blood tests. The hemotologist stated that My tests did not look like leukemia. Now after all the infusions, I am told that they will give me a stronger iron infusion for the next two weeks.
I am stumped and just wondered if there was a correlation because I never had a problem with my blood. I took the booster in September and am worried about taking the second booster when it is approved. I am a fairly healthy 76 year old with moderate high blood pressure and diabetes which is well controlled with A1C below 6. Thank you for any answers you can provide.

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Make your own choice about the booster because we US citizens should be able to do that but I can tell you that I will not be taking a booster. I am the same age as you and have the same issues with my iron since taking the Pfizer vaccine last year. I still work and my company mandated the vaccine to their employees. I firmly believe the cause of my low iron is because of the vaccine which was never tested correctly before rolling it out. Now we are the guinea pigs.

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@stellm

Yes. My husband has never had any history of anemia or low iron. He received the Pfizer vaccine in March. He began feeling more tired over the next two months. He saw his physician and she suspected some type of internal bleeding based on the blood test, He had an upper and lower endoscopy. No internal bleeding was found. They are going to try the camera endoscopy next week. We don't think this is going to reveal anything. His iron, ferritin and red blood cell count is extremely low. The only change in has been receiving the vaccine.

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This is a title in PubMed from Jan 2022. Mayo would not allow me to post the link. “Severe aplastic anemia after COVID-19 mRNA vaccination: Causality or coincidence?”

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@stellm

Yes. My husband has never had any history of anemia or low iron. He received the Pfizer vaccine in March. He began feeling more tired over the next two months. He saw his physician and she suspected some type of internal bleeding based on the blood test, He had an upper and lower endoscopy. No internal bleeding was found. They are going to try the camera endoscopy next week. We don't think this is going to reveal anything. His iron, ferritin and red blood cell count is extremely low. The only change in has been receiving the vaccine.

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This EXACT scenario has just happened to my father. He had his last booster 9/21. Over the last several months he has been short of breath, tingling extremities, dizzies, fatigue. After being passed around to 3 specialists who thought he might have vertigo, someone thought to check his hemoglobin. It was 6! After two pints of blood, three iron infusions, he is only back to an 8.9. Colonoscopy and endoscopy showed no internal bleeding either.

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@samwyyze

This is a title in PubMed from Jan 2022. Mayo would not allow me to post the link. “Severe aplastic anemia after COVID-19 mRNA vaccination: Causality or coincidence?”

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Hi @samwyyze, welcome to Mayo Clinic Connect. I noticed that you wished to post a URL with your post. You will be able to add URLs to your posts in a few days. There is a brief period where new members can't post links. We do this to deter spammers and keep the community safe.

Allow me to post the link to the research for you.
- Severe aplastic anemia after COVID-19 mRNA vaccination: Causality or coincidence? https://pubmed.ncbi.nlm.nih.gov/34920343/

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@sueinmn

After reading all of your reports and comments here, I decided to look at VAERS (Vaccine Adverse Event Reporting System https://wonder.cdc.gov/controller/datarequest/D8) and search for low hemoglobin or low ferritin reports. There were 420,000 adverse events reported out of 330,000,000 Covid vaccine doses administered. Of those 778 reported low hemoglobin or ferritin, 324 of those from the Pfizer vaccine. We cannot tell from this simple search exactly when, in relation to injection, these events were reported. Now is there a cause/effect proven by reporting. To make a comparison, I also looked at reduced ferritin/hemoglobin in VAERS for the Shingrix and Quadravalent flu vaccines (with far fewer doses delivered than Covid) and found 23 for each, out of 30-40 thousand VAERS reports.

I understand that this is undoubtedly underreported, especially since the discovery is coming some time after the vaccine. So, I would say that there appears to be some indication that some people may experience lower hemoglobin at a point after vaccination. In addition, it is known that some people show lower hemoglobin after having the Covid virus (even after a mild case sometimes.)

Perhaps, at some point we will come to a better understanding of all the interactions between Covid infections, the vaccine, and our bodies.

Has anyone experienced either
1) dangerously low hemoglobin of ferritin after vaccination, or
2) numbers that are not recovering?
Sue

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Sue, in your post (dated July 20, 2021) you stated that, "There were 420,000 adverse events reported out of 330,000,000 Covid vaccine doses administered. Of those 778 reported low hemoglobin or ferritin, 324 of those from the Pfizer vaccine.

Would you have a current update on these numbers? I would like to report them to my hematologist (who is currently giving me iron infusions).
Thank you

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