For people taking immune suppressants which COVID vaccine is best?

Posted by strongevergreen @strongevergreen, Dec 2, 2021

For people who regularly take immune suppressant medication, which of the Covid-19 vaccines are most effective ?

Interested in more discussions like this? Go to the Autoimmune Diseases group.

@colleenyoung

Hi Atina, welcome. You'll notice that I moved your question to this existing discussion in the Autoimmune Diseases group. (https://connect.mayoclinic.org/group/autoimmune-diseases/) I did this so you can connect with others like @becsbuddy @strongevergreen @rosemarya @babsstruck @siosal @loribmt who are talking about getting vaccinated while on immunosuppressing drugs.

Since you mentioned psoriasis & psoriatic arthritis, you may also be interested in this related discussion:
– Psoriasis and the covid vaccine https://connect.mayoclinic.org/discussion/psoriasis-and-the-covid-vaccine/

Atina, did you talk to your doctor about the flare of psoriasis? Did s/he suggest any changes to your medication?

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Thank you for your reply; my doctor has retired….trying to find a new one.

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@strongevergreen I have been on immunosuppressants for about 4 years now for my autoimmune disease. My neurologist and oncologist told me to just get the vaccine and they didn’t have a preference of one over another. Ive received 2 Pfizer vaccines and one booster with no change in my health.
What has your doctor recommended? Have you not been vaccinated yet? Why?

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@becsbuddy

@strongevergreen I have been on immunosuppressants for about 4 years now for my autoimmune disease. My neurologist and oncologist told me to just get the vaccine and they didn’t have a preference of one over another. Ive received 2 Pfizer vaccines and one booster with no change in my health.
What has your doctor recommended? Have you not been vaccinated yet? Why?

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I REALLY WANT TO GET THE PFIZER VACCINE !! I had Covid-19 and do NOT want to repeat that experience. I have been seeking answers from my doctor and pharmacists but so far, there is no research data, only clinical reports of individuals. I was diagnosed with MS in 2004 and have been taking Avonex Interferon beta 1-a since the day of my diagnosis. I have had ZERO symptoms and NO relapses since my first episode 18 years ago. I am hesitant to tamper with the status quo since I’ve had such success so far. I live alone and am retired. I order groceries and pay my bills on-line. I have no exposure to other people. I got Covid from a non-symptomatic electrician who came to my home to do some work. I was in his presence only long enough to write a check and hand it to him. Neither of us wore a mask. Ten days later I had ALL the symptoms and made arrangements for my dogs in the event of my death. When I ask for information about the potential interaction between interferon and Covid-19 vaccines, I pretty much only get advised to GET VACCINATED. I don’t need to be persuaded. I already want to be vaccinated. I already know how bad Covid-19 is. I just want to know the answer to this one question. Will the interferon immune suppressant be as effective if I am vaccinated with an immune stimulant ? Put another way, will the Covid-19 immune stimulant be effective if I continue to take an immune suppressant ? Most recently, I put this simple question to the Pfizer Company: Should I stop taking my immune suppressant before being vaccinated with your Covid-19 vaccine ? I’m waiting for an answer. Meanwhile, I am healthy and have no real complaints. I’d like to return to swimming and participate in yoga classes at the YMCA but I don’t dare do that without a Covid-19 vaccine. My Neurologist and I have an appointment next month to decide which route I should follow: Continue Avonex and get the vaccine or stop Avonex and get the vaccine or basically continue to isolate until the pandemic goes away

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Would this work for eczema? Besides the very expensive Dupixent, what else can rid eczema, there has to be something besides prednisone or steroids, help please!!!!!!!!!!!

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@atina

I have been injecting myself with Enbrel since close to 20 years; as a result my psoriasis & psoriatic arthritis has been under control; since I received 2 Moderna jabs plus one Pfeizer booster to protect myself against Covid my psoriasis & psoriatic arthritis have returned. I am asking myself wether it has to do with the vaccins? Enbrel suppresses my immune system but doesn't the vaccins "boost" it? And if I am right isn't possible that this is the reason my psoriasis & psoriatic arthritis have returned?

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I have the same concern. Does the immune stimulant counteract the immune suppressant ? Does the immune suppressant cause the immune stimulant to be ineffective ?

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@atina

I have been injecting myself with Enbrel since close to 20 years; as a result my psoriasis & psoriatic arthritis has been under control; since I received 2 Moderna jabs plus one Pfeizer booster to protect myself against Covid my psoriasis & psoriatic arthritis have returned. I am asking myself wether it has to do with the vaccins? Enbrel suppresses my immune system but doesn't the vaccins "boost" it? And if I am right isn't possible that this is the reason my psoriasis & psoriatic arthritis have returned?

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I posed this question to the Pfizer Company and am awaiting their response.

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Thank you so much but Amgen is the company that makes the drug: are they now part of pfeizer?

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I HAVE AUTO IMMUNE DEFICIENCY AND TAKE WEEKLY INFUSION TREATMENTS (HIZENTRA). MY IMMUOLIGIST SEND BLOOD TEST TO A LAB IN UTAH AND MUCH TO MY CONCERN ALL TESTS CAME BACK NEGATIVE. I HAVE HAD ALL THREE SHOTS AND NONE HAVE GIVEN ME PROTECTION, DO NOT KNOW WHATELSE TO DO, OTHER WEAR MASK AND BE VERY CAUTIOUS.

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I started having MG symptoms on July 25,2019. I was finally diagnosed after 8 months on March 24, 2020 … and have been in remission since 11-27-2020. I did three shots so far with nor soreness or side effects. They were all MODERNA .. in April, May, and December 28th, 2021. My city, Tempe Arizona, has all three. Check your city websites. In our town, they do shots two mornings a week and each week a different school. They had a TEMPE FIRE PARAMEDIC inside, standing by, with all his equipment, watching to see no one had a bad reaction, after their shot, during our waiting to leave period. You could pick the brand you wanted … and the lines were 5 to 8 people long.

My doctor said the shot was safe …. so long as it was DEAD. So avoid any shot with a live virus such as for SHINGLES. I have been safely in remission, am off now all PREDNISONE since 11/2020, still only had 5 original IVIG's, and feel fine except for MG onset Insomnia side effects many nites. So I do not know if the shots work to keep COVIC away … but the shots have not hurt me, or thrown me out of remission. So I feel safe!!!

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@strongevergreen

I REALLY WANT TO GET THE PFIZER VACCINE !! I had Covid-19 and do NOT want to repeat that experience. I have been seeking answers from my doctor and pharmacists but so far, there is no research data, only clinical reports of individuals. I was diagnosed with MS in 2004 and have been taking Avonex Interferon beta 1-a since the day of my diagnosis. I have had ZERO symptoms and NO relapses since my first episode 18 years ago. I am hesitant to tamper with the status quo since I’ve had such success so far. I live alone and am retired. I order groceries and pay my bills on-line. I have no exposure to other people. I got Covid from a non-symptomatic electrician who came to my home to do some work. I was in his presence only long enough to write a check and hand it to him. Neither of us wore a mask. Ten days later I had ALL the symptoms and made arrangements for my dogs in the event of my death. When I ask for information about the potential interaction between interferon and Covid-19 vaccines, I pretty much only get advised to GET VACCINATED. I don’t need to be persuaded. I already want to be vaccinated. I already know how bad Covid-19 is. I just want to know the answer to this one question. Will the interferon immune suppressant be as effective if I am vaccinated with an immune stimulant ? Put another way, will the Covid-19 immune stimulant be effective if I continue to take an immune suppressant ? Most recently, I put this simple question to the Pfizer Company: Should I stop taking my immune suppressant before being vaccinated with your Covid-19 vaccine ? I’m waiting for an answer. Meanwhile, I am healthy and have no real complaints. I’d like to return to swimming and participate in yoga classes at the YMCA but I don’t dare do that without a Covid-19 vaccine. My Neurologist and I have an appointment next month to decide which route I should follow: Continue Avonex and get the vaccine or stop Avonex and get the vaccine or basically continue to isolate until the pandemic goes away

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I take Actemra for autoimmune disease. Got 3 shots. Antibodies only 130 need 250. By now who knows. Could be 0. Drug was moderna.

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@marilynredder2367

I take Actemra for autoimmune disease. Got 3 shots. Antibodies only 130 need 250. By now who knows. Could be 0. Drug was moderna.

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How do you find out what your anti-body level is? It is not common practice at my clinic, which is Mayo Health system in Wisconsin, to have a doctor order this test even for those of us who are immuno-compromised.

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@marilynredder2367

I take Actemra for autoimmune disease. Got 3 shots. Antibodies only 130 need 250. By now who knows. Could be 0. Drug was moderna.

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Thanks for responding!

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