How long does it take for Tymlos side effects to subside?

Oh gee, I was not implying you were a needle phobe. Needle phobia is a real obstacle to treatment for some, though and is not a pejorative term. The thing is the slow release patch is not effective. I have central vertigo, inner ear issues and vestibular migraine so I understand the loss of balance (along with 7 spinal fractures). But I have not had that issue with Tymlos myself, except for the first week or two.

As with my cancer meds, I don't think that effectiveness is possible without side effects, at least for some of us. Side effects may be a byproduct of the very mechanism that makes the drugs work.

Thanks. I'll look him up. I think regenerative medicine is the wave of the future but won't get approved by the FDA because big drug companies would falter. I also wonder why Asia is so healthy with the holistic approach! Just my thoughts.

@mariajean03 rates of osteoporosis are higher in Japan and about the same overall in China, as examples, compared to the US:

According to a systematic and meta-analysis study in China, the prevalence of osteoporosis from 2003 to October 2015 was reported to be 15.33% in men and 25.41% in women. It can be concluded that the overall prevalence of osteoporosis was 20% [94].

In a study, the prevalence of osteoporosis was assessed in several industrialized countries (USA, Canada, five European countries, Australia, and Japan) and people aged 50 and over. The prevalence of osteoporosis in the spine or hip was reported as follows: 26.3% in Japan, 21% in the USA, 14.3% in Germany, 9.9% in France, 9.7% in Italy, 7.8% in the United Kingdom, 6.3% in Spain, 2.6% in Canada, and 2% in Australia. Overall, the number of people with osteoporosis is estimated at 49 million.

Also:
"The results of subgroup analysis also show that among men, the highest prevalence of osteoporosis was in Asia and among women, the highest prevalence of osteoporosis was in Africa."

It is easy to find other articles or studies on osteoporosis in countries in Asia, if you are interested.

I’m also finding that the side effects are quite variable from day to day. I chose to administer the medication after dinner when I settle down to watch tv. Shortly after administering it, I am slammed with a headache and nausea but it frequently fades in several hours. Earlier this week I had several days of low back pain. This morning the headache and nausea are still present. While annoying and definitely uncomfortable I’m able to manage/tolerate the side effects, at this point. I will consider clicking down if they become worse. Although I never know what the day will be like it’s evident that there will be some side effects.

With my current osteoporotic fractures and fear of future fractures and more limited mobility or lifestyle restrictions, Tymlos is extremely important treatment.

Does anyone take anything to get rid of the headaches and does it help?

I was mistaken in assuming the Tymlos patch was slow release. It was applied for 5 minutes a day. In a phase 3 trial, the patch was less effective than injections and had more adverse reactions reported. However, fewer people dropped out because of those reactions so the patch may be slightly ssfer.

Not interested. But thank you for your research.

@njhornung it sounds like 5 minutes was too "slow" of a "release"!

I took a 42 hour break and went back to 4 and have the same lightheaded
headache experience , I did salt and food etc before and water electrolyte
drink, I think possibly if I do the whole thing late at night starting
tomorrow night like 11 pm and just go to sleep for side effects

@cloud60 I just hope you don't wake up to side effects. I just had side effects 9-12am with 7 clicks but now they are gone. Overall fatigue remains no matter what I do so I get myself going. I still get woozy/lightheaded with 7-8 clicks but have not had a headache since my first two weeks in 6/21. I was hoping yours would go away.

Originally I could not tolerate 4 clicks. Hope that gives you hope.