Has anyone used Mucomyst (acetylcysteeine nebulization?

Posted by dulwich @dulwich, Aug 3, 2023

I would be interested in hearing about your experiences- was it helpful in loosening sputum and were there side effects or other inconvenience?

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@sueinmn

@dulwich I use N-acetylcysteine in tablet form, twice a day, to help thin mucus. It has helped me avoid exacerbations caused by an accumulation of thick, sticky mucus. That has been a problem of mine for many years, and the NAC seems to make is less sticky, both in my sinuses and lungs.
Sue

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Hi Sue, at the present time I take Guaifenison 600 ER tabs twice a day to thin mucus due to my Bronchiectasis diagnosis. Due you feel adding the NAC 600 thinned it even more for you, or just that one works better than the other. I’m willing to try both to help thin the excessive mucus i experience on a daily basis.

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@sueinmn

Yes. Both thin mucus. N AC also has some anti-inflammatory properties. It may also protect kidneys and based on health and family history I am at risk for kidney disease.
Sue

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@sueinmn Let me see if I understand, you take NAC and mucinex/guaifenesin at the same time, twice a day before nebbing?

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@scoop

@sueinmn Let me see if I understand, you take NAC and mucinex/guaifenesin at the same time, twice a day before nebbing?

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Hi Scoop & @spider109, I take both as part of my daily med/supplement routine. Upon rising in the AM and again between 8-10PM. As oral meds, they take some time (days) to be really effective in the body. I also use a Symbicort inhaler twice a day.

LET ME STRESS, this is a routine that I have worked out for my own particular thick, sticky mucus that has plagued me all my life. I have also had asthma & severe allergies for many years. My primary and pulmonologist are happy with how it works for me. You and your body are different, and your situation may vary.

My ENT started me on the Mucinex nearly 40 years ago to help with persistent inner ear fluid (that when drained resembled thick yellow glue) and thick sinus mucus - both of which led to dozens of infections. It cut the infections to 1-2 per year from 10 or more.

After I was diagnosed with MAC & Bronchiectasis 5 years ago, I learned about NAC/glutathione here and on another Bronch site. I did some research and decided to give it a try. But I was unwilling to inhale liquid glutathione as I have highly reactive airways and was afraid to add one more substance. Also, the NAC has anti-inflammatory properties and I have arthritis & other inflammatory issues, so I thought, hmmm... It helps me.

Finally, unless I am having a flare or exacerbation, I no longer neb saline twice a day, though I faithfully do airway clearance. My "magic number" for nebs this summer has been just 2-3 per week (I don't currently seem to have MAC) preceded by my Symbicort inhaler. Let me say, I really though I was walking a dangerous line there - or being a "slacker" until I watched one of the videos from the recent European Bronchiectasis conference where I learned it is an acceptable practice for stable situations:
https://www.youtube.com/watch?v=Z2B-yX299pI

What routine do you use?
Sue
PS I did some stretching & meds before I sat down to read Connect. Now my lungs are ready to clear so I am blowing on my Aerobika and huffing as I write. Multitasking at its finest.

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@sueinmn

Yes. Both thin mucus. N AC also has some anti-inflammatory properties. It may also protect kidneys and based on health and family history I am at risk for kidney disease.
Sue

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Hi Sue, what brand of NAC can you recommend? And can you compare ACC to NAC?
Inna

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I take Carbocisteine to thin mucus and it definitely helps me. I tried NAC a while ago, it disagreed with my stomach.

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@sharon482

I take Carbocisteine to thin mucus and it definitely helps me. I tried NAC a while ago, it disagreed with my stomach.

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What form and brand of Carbocisteine do you take and where can you get it? Have you compared it to Mucinex?

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I was just proscribed mucomyst and have had two sessions inhaled. I like it (despite the smell) and I think it made my mucus thinner than 3 percent saline which was irritating my throat. I am in hospital at the moment and they are giving me 600 mg 20 percent 2 x a day. I hope medicare will pay when I get out. It feels smoother than salt solution somehow and the smell is tolerable.

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@sueinmn

Hi Scoop & @spider109, I take both as part of my daily med/supplement routine. Upon rising in the AM and again between 8-10PM. As oral meds, they take some time (days) to be really effective in the body. I also use a Symbicort inhaler twice a day.

LET ME STRESS, this is a routine that I have worked out for my own particular thick, sticky mucus that has plagued me all my life. I have also had asthma & severe allergies for many years. My primary and pulmonologist are happy with how it works for me. You and your body are different, and your situation may vary.

My ENT started me on the Mucinex nearly 40 years ago to help with persistent inner ear fluid (that when drained resembled thick yellow glue) and thick sinus mucus - both of which led to dozens of infections. It cut the infections to 1-2 per year from 10 or more.

After I was diagnosed with MAC & Bronchiectasis 5 years ago, I learned about NAC/glutathione here and on another Bronch site. I did some research and decided to give it a try. But I was unwilling to inhale liquid glutathione as I have highly reactive airways and was afraid to add one more substance. Also, the NAC has anti-inflammatory properties and I have arthritis & other inflammatory issues, so I thought, hmmm... It helps me.

Finally, unless I am having a flare or exacerbation, I no longer neb saline twice a day, though I faithfully do airway clearance. My "magic number" for nebs this summer has been just 2-3 per week (I don't currently seem to have MAC) preceded by my Symbicort inhaler. Let me say, I really though I was walking a dangerous line there - or being a "slacker" until I watched one of the videos from the recent European Bronchiectasis conference where I learned it is an acceptable practice for stable situations:
https://www.youtube.com/watch?v=Z2B-yX299pI

What routine do you use?
Sue
PS I did some stretching & meds before I sat down to read Connect. Now my lungs are ready to clear so I am blowing on my Aerobika and huffing as I write. Multitasking at its finest.

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Did you get BE from recurrent pneumonia? I had recurrent sinus/ear infections which would linger and move to my chest and cause pneumonia. I'm only 32 and now have tubular bronchiectasis.

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@liz440

I was just proscribed mucomyst and have had two sessions inhaled. I like it (despite the smell) and I think it made my mucus thinner than 3 percent saline which was irritating my throat. I am in hospital at the moment and they are giving me 600 mg 20 percent 2 x a day. I hope medicare will pay when I get out. It feels smoother than salt solution somehow and the smell is tolerable.

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update: the resp therapist in hospital here just told me the mucomyst inhalation was only for a few days and it was discontinued. It did help but she said they don't use it for long because it can cause bronchospasms. I think they will replace it with the saline inhalation but am waiting on the doctor to arrive.

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@mjgreenleaf

Did you get BE from recurrent pneumonia? I had recurrent sinus/ear infections which would linger and move to my chest and cause pneumonia. I'm only 32 and now have tubular bronchiectasis.

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My original pulmonologist thought it was the result of long-term asthma, extensive exposure to irritants (paper dust, asbestos and soil particles) and repeated bouts of bronchitis and pneumonia, going back to childhood. In addition, I meet the criteria for "Lady Windemere Syndrome" - older female, slight frame and lifelong low body weight.

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