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GLP1 and no weight loss

Posted by marywnord @marywnord, May 27 9:25am

I’ve been on Zepbound for 6 weeks and I’m seeing no results. Thoughts?

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tarakeeg | @tarakeeg | 5 hours ago
In reply to @lisalucier "@tarakeeg - welcome to Mayo Clinic Connect. That's rough that your tirzepatide (Zepbound) is having very..." + (show)
Profile picture for Lisa Lucier, Moderator @lisalucier

@tarakeeg - welcome to Mayo Clinic Connect. That's rough that your tirzepatide (Zepbound) is having very little or no effects.

I moved your post here where another member was talking about a similar situation with tirzepatide (Zepbound):

- GLP1 and no weight loss https://connect.mayoclinic.org/discussion/glp1-and-no-weight-loss/

Fellow members here such as @sandylakes @celia16 @samwho and others may also have some input on being what you called a slow responder.

I am not a medical professional, but personally, I, too, have dealt with this. I took tirzepatide (Zepbound) 2 years ago when I lost 53 pounds on semaglutide (Wegovy), but had terrible GI side effects. I got all the way up to the top dose of tirzepatide (Zepbound), and my insurance said I'd maxed my coverage. I had only lost 1 pound on it by then.

My husband did not lose any weight on tirzepatide (Zepbound) till he got to the highest dose.

What does your medical professional overseeing your care say about this lack of effect so far?

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@lisalucier Thank you, I get the Zepbound from Ro.co, they are not very helpful. I am trying to find a doctor I can see in person, though not sure how to find one with experience with Zepbound.

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tarakeeg | @tarakeeg | 5 hours ago
In reply to @susiesmith "@tarakeeg I also struggled with losing weight at 10 mg a week, so my doctor increased..." + (show)
Profile picture for susiesmith @susiesmith

@tarakeeg I also struggled with losing weight at 10 mg a week, so my doctor increased the dose to 20 mg a week. I still am a slow loser (4 pounds a month), but my weight loss is steady. Maybe ask for an increase.

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@susiesmith they can go up to 20mgs? 15mgs is the highest dose approved but do doctors prescribe 20mg off label? That would be nice since I'm worried about having no room to increase.

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susiesmith | @susiesmith | 2 hours ago
In reply to @tarakeeg "@susiesmith they can go up to 20mgs? 15mgs is the highest dose approved but do doctors..." + (show)
Profile picture for tarakeeg @tarakeeg

@susiesmith they can go up to 20mgs? 15mgs is the highest dose approved but do doctors prescribe 20mg off label? That would be nice since I'm worried about having no room to increase.

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@tarakeeg Yes

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tarakeeg | @tarakeeg | 51 minutes ago

Thank you, that's helpful.

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