GLP-1 Drugs Causing Arrythmias

I started taking semaglutide about 5 months ago. During the last 30 days on semaglutide, GLP-1, my dosage was increased. I’ve lost about 20lbs on it. I had a history of Afib and 7 years ago had a heart ablation because I didn’t want to be on blood thinners and heart rate meds for the rest of my life. I’ve had no reoccurrence of Afib for 7 years. All of a sudden last month I went into persistent Afib. I went to urgent care and have spoken to a few doctors and no one seems to know anything about a relationship between GLP-1 and Afib. Everything on the internet says GLP-1 should actually help with AFIB because of weight loss. I stopped taking Semaglutide 2 weeks ago but am still in AFIB. I will be seeing a Mayo cardiologist in a few weeks.
Anyone else have any experience with GLP-1 and AFIB

I don't have experience in this, but I do know that there must be a close causal link established in literature before one should begin to speculate about such links. There is the 'post hoc, ergo propter hoc' fallacy in thinking that, I got drunk last night, but I woke up with a tattoo. It must mean that drinking caused me to break out in a tattoo.

People try something novel and later experience an unwanted or unpleasant episode of some kind of corporeal behaviour. Unless there can be a direct causal link, one should assume that there's at least the same probability that the episode was going to happen without the novel introduction.

About the recurring AF after 7 years - this is exceedingly common, even among AF sufferers who DON'T take GLP-1. It has been known for years that AF is a progressive disorder. Even after an apparently successful ablation (the patient is free from arrhythmias for one full year after the procedure), that same patient may find that they're back in AF the next month...Month #13. Or, it might take three or six years. A surprisingly, dismayingly, large number of all ablated AF sufferers will need at least a touch-up ablation at some point in the future. Again, it's exceedingly common, and doesn't have to be associated with GLP-1 usage. I t has to do with the heart developing new re-entrant foci at places other than where the previous ablation allowed the intrusion of electrical impulse into the left atrium.

I have heard of it. I have been following any group like this for the same reason. I believe the drug causes increased heart rate and it also effects the heart in other ways. My husband has CHF and was actually cleared to take the drug. After being on it 3 months and losing 20lbs, his defibrillator went off. He now has afib and tachycardia. The last afib said it lasted 34 minutes. I can only speculate the meds are responsible.

My personal experience is that my resting heart rate did in fact increase upon taking semaglutide. I have POTS and had some issues with low heart rate prior to starting the GLP-1.

I had open maze surgery in Oct 2010, I was in Afib 100% of the time after wearing a 30 day heart monitor. Everything has been fine for 14.5 years or until the night of 4/10 somewhere in the 9-10pm hour a switch flipped and I went into Afib Flutter 100% of the time. My Dr. mentioned back then it could come back. I never took any heart medication after full recovery.

Me almost same exact story has ablation march 28,took shot sunday nite wed fell back into afib after having negative readi as on my watch for month and a half ,now on more meds ,waiting on 2nd ablation have stopped zepbound after only 1 shot cause I read an article about afib and zepbound

I get random premature ventricular contractions (PVCs) and have for years. They typically only last a few minutes to a few hours, and only 1-2 a minute max. Since starting semaglutide, I've experienced much more frequent PVCs within a day or two after injecting. Although I'm on a lower dose now, last night (a day after injecting), I was experiencing basically nonstop PVCs followed by frequent but not constant PVCs, which made me feel dizzy and like I couldn't get a full breath.

Although arrythmia isn't listed as a side effect in the trials, on the meds, my experience and anecdotal evidence from online message boards leads me to believe that at least some of us definitely get an arrythmia from the medication. I think more instances of this will come out the longer the drug is on the market.