Getting off of Seroquel

Posted by anniegk @anniegk, Jun 8, 2018

I have been on 300 mgs. Seroquel ER for over a year for augmenting my antidepressant which is 45 mgs. Of Mirtazapine. I decided to try and get off of the Seroquel. I was on 300mgs ER (extended release). I titrated down to 250 mg ER for 2 months without too many problems.than i titrated down to 200mgs ER just 5 days ago. My plan is to try to titrate off using ER tablets. My thinking is that perhaps the drug will remove its self from my system more gradually. I have had some nausea and a couple of episodes of diarrhea. I also have a very irregular heart beat and was started on 60 mgs of Propranolol ER (extended release) 4 weeks ago. It seems to be helping my heartbeat. I have wondered if the nausea and light headness is from the Propranolol, a Beta Blocker, or the dose reduction of the Seroquel. I also wonder if the way iam titrating the Seroquel is safe. My doctor says it will only take a couple of weeks…I think that is too fast of a taper after being on a drug for over a year. What do you think?

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Hello everyone I am new around here!
I am a 20 y/o male and when I was 7 years old I was put on Quetiapine. I believe it was for anxiety or something but I do not remember much of my childhood. Anyways fast forward to now and I have been taking Quetiapine for 13 years and I don't even know why I am taking it. I am currently taking Quetiapine 50mg ER once a day at 5:30-7pm each day. My doctor tried to ween me off last year around this time by cutting my down to 25mg daily for 2 weeks followed by 25mg every other day for 4 days, after that I went cold turkey. The withdrawal was okay at first but eventually I think I had a panic attack or something and was put back on it. Anyways, my question is how can I got off this drug I've been on for 13 years? Im worried about the effects on my liver and other cognitive effects such as it being incredibly difficult to wake up

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@tness360

Hello everyone I am new around here!
I am a 20 y/o male and when I was 7 years old I was put on Quetiapine. I believe it was for anxiety or something but I do not remember much of my childhood. Anyways fast forward to now and I have been taking Quetiapine for 13 years and I don't even know why I am taking it. I am currently taking Quetiapine 50mg ER once a day at 5:30-7pm each day. My doctor tried to ween me off last year around this time by cutting my down to 25mg daily for 2 weeks followed by 25mg every other day for 4 days, after that I went cold turkey. The withdrawal was okay at first but eventually I think I had a panic attack or something and was put back on it. Anyways, my question is how can I got off this drug I've been on for 13 years? Im worried about the effects on my liver and other cognitive effects such as it being incredibly difficult to wake up

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Hello, @tness360, and welcome to Mayo Clinic Connect. Since you posted about tapering off of quetiapine (Seroquel), I've moved your message here so that you could meet other like @mxyzptlk @highserotonin30 @anniegk @yangedd @linda66 and others, who may have some input on this process.

@tness360 – did your doctor have a different tapering plan for you to try this time to wean off?

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Ben and Seroquel for years he was up to 600

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@tness360

Hello everyone I am new around here!
I am a 20 y/o male and when I was 7 years old I was put on Quetiapine. I believe it was for anxiety or something but I do not remember much of my childhood. Anyways fast forward to now and I have been taking Quetiapine for 13 years and I don't even know why I am taking it. I am currently taking Quetiapine 50mg ER once a day at 5:30-7pm each day. My doctor tried to ween me off last year around this time by cutting my down to 25mg daily for 2 weeks followed by 25mg every other day for 4 days, after that I went cold turkey. The withdrawal was okay at first but eventually I think I had a panic attack or something and was put back on it. Anyways, my question is how can I got off this drug I've been on for 13 years? Im worried about the effects on my liver and other cognitive effects such as it being incredibly difficult to wake up

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@tness360, I assume you are taking regular Seroquel and not Seroquel XL? The smallest dose you can get for XL is 50 mg, so tapering down isn't possible. For some reason, the company believes that quitting from 50 mg to zero is OK. It isn't. I've tried it.

Have you tried cutting your 20 mg pills into smaller bits? Another option is to ask your pharmacist to make a liquid formulation so you can go down in tiny decrements over a long time, even mg by mg. British psychopharmacist, Heather Ashton, has designed a very slow withdrawal protocol for benzos which may work for Seroquel. I don't know. Something to talk over with your doctor and pharmacists.

Also, I can't believe they put you on Seroquel at age 7! IMO, that constitutes malpractice.
https://www.benzo.org.uk/manual/

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@flpatt

Ben and Seroquel for years he was up to 600

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Hi, @flpatt – welcome to Mayo Clinic Connect.

Just wanted to clarify if you were taking quetiapine (Seroquel) for years, or if it was someone else in your family? Are you (or they) now continuing or weaning off of this medication?

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@fplatt, here is some info on how to taper down on Seroquel. It involves some nutritional support known to help with nervous disorders. Again, talk with your MD!
http://www.townsendletter.com/FebMarch2013/whattodo0213_2.html

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I was on 600 seroquel dr refused it to200over6mo was on paxil &wellbutrin took my self off wellbutrin cold turkey,the paxil I tapered down I'm now off lowered seroquel 3days ago to100 getting kinda scared was on all these drugs for over 5yrs don't want an episode has anyone got off seroquel sucessfully?

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@lisalucier

Hi, @flpatt – welcome to Mayo Clinic Connect.

Just wanted to clarify if you were taking quetiapine (Seroquel) for years, or if it was someone else in your family? Are you (or they) now continuing or weaning off of this medication?

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Its me flpatt yes I'm trying weaning on down

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@flpatt

Its me flpatt yes I'm trying weaning on down

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@flpatt – thanks for the clarification. How's the taper going?

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Hi I'm new on here.. Just had a question.. I've been on 50mg of seroquel at night for 2yrs for sleep & anxiety.. I've been trying to taper off for the last few weeks because it's always caused my heart to race after I take it for some odd reason.. I was just wondering if there's any antipsychotics that don't cause the racing heart effect & what is a really good alternative when getting off this medication to help me get a little sleep at night? Are there any sedating antihistamines that I could switch to that won't cause as much heart problems? I was wondering too is it normal to have racing thoughts at night when tapering.. Thanks so much

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@num1boxer1919

Hi I'm new on here.. Just had a question.. I've been on 50mg of seroquel at night for 2yrs for sleep & anxiety.. I've been trying to taper off for the last few weeks because it's always caused my heart to race after I take it for some odd reason.. I was just wondering if there's any antipsychotics that don't cause the racing heart effect & what is a really good alternative when getting off this medication to help me get a little sleep at night? Are there any sedating antihistamines that I could switch to that won't cause as much heart problems? I was wondering too is it normal to have racing thoughts at night when tapering.. Thanks so much

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Hi, @num1boxer1919 – welcome to Mayo Clinic Connect. I can imagine you would be very uncomfortable with the heart racing from the quetiapine (Seroquel), and it's understandable you are looking for an alternative.

If you click on VIEW & REPLY in your email notification, you will see the whole discussion and can join in, meet, and participate with other members talking about their experiences.

I'd invite @flpatt @anniegk @yangedd @highserotonin30 @mxyzptlk @tness360 to return and speak to their experiences with quetiapine (Seroquel) and any heart racing they may have encountered, and share any thoughts they may have on alternatives for antipsychotics or insomnia.

I'd also suggest looking at this thread on insomnia in our Sleep Health group, which may have lots of ideas for you and would be a great place to interact with others who are trying to get better sleep https://connect.mayoclinic.org/discussion/josephene-i-am-having-terrible-insomnia-as-well-nothing-seems-to-help.

Have you had the chance to ask the prescribing doctor for the quetiapine (Seroquel) for an alternative, or some means to deal with the heart-racing side effect, @num1boxer1919? Are you getting much sleep right now?

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@lisalucier

Hi, @num1boxer1919 – welcome to Mayo Clinic Connect. I can imagine you would be very uncomfortable with the heart racing from the quetiapine (Seroquel), and it's understandable you are looking for an alternative.

If you click on VIEW & REPLY in your email notification, you will see the whole discussion and can join in, meet, and participate with other members talking about their experiences.

I'd invite @flpatt @anniegk @yangedd @highserotonin30 @mxyzptlk @tness360 to return and speak to their experiences with quetiapine (Seroquel) and any heart racing they may have encountered, and share any thoughts they may have on alternatives for antipsychotics or insomnia.

I'd also suggest looking at this thread on insomnia in our Sleep Health group, which may have lots of ideas for you and would be a great place to interact with others who are trying to get better sleep https://connect.mayoclinic.org/discussion/josephene-i-am-having-terrible-insomnia-as-well-nothing-seems-to-help.

Have you had the chance to ask the prescribing doctor for the quetiapine (Seroquel) for an alternative, or some means to deal with the heart-racing side effect, @num1boxer1919? Are you getting much sleep right now?

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Thanks so much for the reply really appreciate it.. & I will definitely look at that thread… & to answer your question yes i have asked my doctor she considered Zyprexa but I looked at the side effects & it said it can cause racing heart beat as well so I was a little cautious on taking it.. She didn't mention anything else tho.. & No not really sleeping well at all.. Just a lot of awakings through the night & times where I can't go back to sleep, leaves me pretty sick the next day not very fun lol.. The first year I was on it, it worked very well but this past year has been pretty rough.. I don't know if it's just lost its effectiveness or what.. Never had sleeping problems at all before starting on anxiety meds just doesn't make much sense.. If any possible ideas come to mind I would greatly appreciate it..

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