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gene therapy to reverse bronchiectasis?
Hi community,
Early this year the FDA granted the human clinical trial of ER-100. ER-100 is an investigational gene therapy designed to reverse vision loss by restoring aged and damaged ocular cells to a younger, healthier state.
We bronchiectasis patients should push this idea for reversing bronchiectasis. To me the damage to our lungs is similar to the damage of vision caused by glaucoma. But glaucoma is a well-known disease, while bronchiectasis is not. How can we have our voice heard and push the research going towards this direction sooner? Most people who have bronchiectasis are older, so we may not be able to see this happen; who knows? But the young people certainly have the chance.
I raise the idea here because I truly believe that gene therapy can restore our damaged lungs. So what do you think and what should we do?
Ling
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Once the lung is damaged it cannot be repaired. Gene therapy however can be used to alter the underlying cause and can slow down or halt the progression of the disease. The damaged part of the lungs is essentially non functional. You cannot bring it back from the dead so to speak.
@sandpiper49 Yes irreversible,the airways are widened,but early phase 1 trail results in humans is promising using there own lungs cells (P63 basal stem cells),