Anyone else out there with extremely high lipoprotein (a)?

Posted by csage1010 (Sue) @csage1010, Feb 21, 2022

Hi! I just found out that I have an extremely high lipoprotein (a) of 515 nmol/L. I'm terrified; it's that high. I'm 58 years old and my total cholesterol is 212. My LDL is 141, and my HDL is just 40. My cholesterol/HDL ratio is 5.3. Of course it's a long weekend and I may not be able to reach my doctor tomorrow. I have watched a couple of informational sessions online from various doctors discussing elevated LP(a), but no one mentions anything close to how high mine is. Is there anyone else out there with severely elevated Lp(a)? Thanking you in advance. Sue M.

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Profile picture for cece425 @cece425

Be sure to read about the side effects of Repatha.

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Every drug has side effects, Repatha is no different. Thankfully, I'm not feeling any.

And yes, we might find out some years from now that while it can lower LDL, there are other effects that are not good. See the Niaspan (niacin) studies, for which I was a part and took it daily for 10+ years. Each has to make a decision what risks they want to take.

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Profile picture for cece425 @cece425

Stanford has one coming up soon.

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What level trial? It would be nice to jump in when there is no placebo. Does that ever happen in trials at the end? Final stage?

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Profile picture for rosie66 @rosie66

Wow that repatha sounds like magic. I read there really wasn’t much that helped. And it seems such a big number, as you say is hard to budge. So you are probably ok now? Thanks for your response

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Be sure to read about the side effects of Repatha.

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Profile picture for tia50 @tia50

Lilly is doing a clinical trial.

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Stanford has one coming up soon.

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Profile picture for csage1010 (Sue) @csage1010

I have thought about it. Those ideas all sound very good. I even like salsa on salad, with a tiny bit of plain non-fat yogurt mixed in. I can do mostly vegan/low-fat and play around with the spices and herbs, especially those that have anti-inflammatory properties. Thank you for all you good advice.

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A low dose statin to lower your LDL, exercise for overall health benefits,
a healthy diet for overall health benefits: All of the above is
important according to Stanford Cardiology, Peter Attia, Dr. Steven Nissen.
None will lower your AP(a) because genetic but can help with other
risk factors for heart disease.

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Profile picture for tia50 @tia50

Are you still on a Vegan diet?

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heavily plant based with some fish (tuna and salmon mostly) and perhaps 1 meal a week might have grilled chicken

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Bio on the Graedons ... https://www.wunc.org/people/joe-terry-graedon

I've heard the show on NPR, but this article sounds as if it is written by a medical professional - it does not appear Joe Graedon, the author, fits this profile. He is a pharmacist or least trained as, and she is an anthropologist.

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@saganjames, it looks as if the People's Pharmacy is centered around the sharing of experiences to help others make more informed decisions, much like Mayo Clinic Connect. When looking at the article you shared, it is a bit confusing in how it is presented as it does feel as though it is a Q&A with a medical professional which I do not believe the People's Pharmacy has as part of its broadcast and writing crew.

@saganjames, if you don't mind sharing, which part of the article did you find most interesting or helpful?

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Mine is 329.1 Susan. You can read what happened to me in an earlier message. I am going to get in a study for Eli Lilly. I am hoping I don't get the placebo. It is for the drup Lepodisirin. So far it can bring lipoproteinA down 94%. Search for the studies online. I feel for me that is the best thing to do.

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