Extreme fatigue from Metoprolol?

Posted by afm @afm, Feb 11 12:11pm

Hello,
I am a 77 year old male who has been very active - Kiliminjaro, Inca Trail, Mt. Langley and White Mountain (14,000 ft) 2 years ago. After experiencing "chronic fatigue" I have been diagnosed with both SVT and afib and am currently on a 50 mg per day dose of Metoprolol which has eliminated both the SVT and afib. After recovering from ankle and shoulder replacement surgery I have been having trouble getting back into hiking/backpacking. Ankle and shoulder are fine and hiking at sea level on flat ground is no problem. However when I add climbing (4 - 7 miles with 1000 - 2000 ft of climbing) I run into problems - start breathing very heavily and become light headed and dizzy. I have read that the beta blocker Metoprolol limits maximum heart rate which is most likely the cause of this. Any others out there with the same issue? Comments? Any solutions? I am working closely with my cardiologist on this.

Thanks

Interested in more discussions like this? Go to the Heart Rhythm Conditions Support Group.

Curious as to why your cardiologist has you on Metropolol after ablation, especially with your resting heart rate so low and apparently no AF. 150 bpm while doing extreme exercise like Xcountry skiing seems normal result.
I recommend a second opinion. Of course, the cardiologist joke is: "Ask 5 cardiologists a question and you'll get 5 different answers."

REPLY
Profile picture for nevets @nevets

@afm
I am currently on a daily dose of 25 mg metoprolol and I don't really notice it. When I go cross country skiing my HR will sometimes go above 150 BPM and then return to 50-60 BPM at rest. Prior to my ablation in January 2025, I was taking 75 mg of metoprolol, which gave me a case of the zombies. After the ablation, my cardiologist lowered my dose to 50mg, then to 25mg, and said I can discontinue it altogether is my HR goes to 50 or below during rest. When sleeping, my Apple Watch often clocks my HR in the mid 40s.

Jump to this post

@nevets Thanks. I heard back from my cardiologist today who recommended cutting back to 25 mg of Metoprolol but I did have similar heart rate problems at that dosage as well. He mentioned other medication options but didn't elaborate. I also asked again about a possible catheter ablation procedure.

REPLY

Had extreme fatigue on Metropolo 50. My cardiologist suggested changing my prescription from 50 at once to 25 mil 2x a day it worked, I felt more energetic, you are lucky your afib gone mine never changed but doing ok!

REPLY
Profile picture for bubbzy5569 @bubbzy5569

Had extreme fatigue on Metropolo 50. My cardiologist suggested changing my prescription from 50 at once to 25 mil 2x a day it worked, I felt more energetic, you are lucky your afib gone mine never changed but doing ok!

Jump to this post

@bubbzy5569 Thanks for the reply. I cut back from 50 to 25 mg and felt a big sluggish the first day. Probably won’t get out into the hills for a few days due to rain.

REPLY

I hope you're doing 25 twice a day. If you need 50 it just needs to be split in half because 50 at one shot is to much for your body to process. That's how it was explained to me. Good Luck - Feel Better

REPLY
Profile picture for afm @afm

@bubbzy5569 Thanks for the reply. I cut back from 50 to 25 mg and felt a big sluggish the first day. Probably won’t get out into the hills for a few days due to rain.

Jump to this post

@afm I had drowsiness with metroprolol at first. Now I just take it at night instead of in the morning. That resolved the drowsiness.

REPLY
Profile picture for roslansky @roslansky

@afm I had drowsiness with metroprolol at first. Now I just take it at night instead of in the morning. That resolved the drowsiness.

Jump to this post

@roslansky Thanks. That’s what I am now doing. 25 mg once a day in the evening.

REPLY

I take another beta blocker, atenolol, for both arrhythmias and blood pressure, and it helps, but I have a different perspective on it. My modestly extreme sport used to be bicycle rides which elevated heart rate significantly for an hour or three at a time. I had already mostly stopped that for health and safety reasons before starting on the beta blockers, but the moment I tried them and so much as went for a walk I realized my heart rate was simply not responding directly to exercise - or stress. I felt this to such a degree I talked to my PCP and cut my dosage to about 1/4 of what is normally already a low dose. This still helped, without leaving me feeling helpless.

BUT here's the thing, once you need to be on these things perhaps it's just not a good idea to continue to do physical exercise at those old levels. No medicine is magic, they do what they can but they will have side effects and they don't make you thirty years younger. You have to find a balance of drugs and your conditions and your activities and no two people will be quite the same.

REPLY

IHC has just moved to a new system for patient information. In looking at my history of blood workups, I see that I had low iron at some point a couple of years ago. I took an iron pill last night and woke up feeling better than I had been feeling. Maybe the Metoprolol was not making me tired. My yearly exam and blood work isn't till June. In the meantime, think I'll take the over the counter dose of iron and see if this "feel better" increases. Plus I have a follow up in three month with my pulmonologist and perhaps my oxygen numbers will look better. You are correct, @carbcounter, we are all different and react differently. Sometimes we just need a bit of trial and error or trial and success.

REPLY
Please sign in or register to post a reply.