Evenity is suggested by my Encrinologist, but not sure what to do

Posted by dswags @dswags, Jun 7 4:34pm

My Dr wants to start me on Evenity. My scores are Spine -2.4, Femoral neck -2.6, Total hip -1.6, But then I also was told I -2.9, not sure how these scores work. My health issues before even starting is I already have Gerd, off/on pain in my middle back, sciatic nerve issue, Arthritis (hands, back). Never had a fracture or broken bones. I take Alendonate now for about 2 years and took it about 10 years ago for a 5 year period. I'm told the inside of my bones are strong but the outside is deteroriating. Reading reviews, I really wonder why I should do this when I'm not feeling bad, feel aches/pains but nothing major. Almost feel like this could be like a cancer treatment. Very concerned!

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It would be helpful to know your age. Your DEXA scores aren't that severe, only your femoral neck is slightly above the osteoporosis range. Take time to do some research so you are comfortable with your decision. Remember that bones change very slowly, so you have time to do this.

Also, after Evenity you will have to go back on a bisphosphonate to keep your gains. Since you already have GERD, oral Fosamax might aggravate that. There's Reclast infusions, so you will want to research them also.

These articles might be helpful: https://prospluscons.com/pros-and-cons-of-evenity/
https://melioguide.com/medications/evenity-a-physicians-perspective/
This article is titled: Forteo®, Tymlos® and Evenity®: How Much Do They Really Reduce Fracture Risk?
https://betterbones.com/bone-drugs/anabolic-treatment/

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Profile picture for daisy17 @daisy17

It would be helpful to know your age. Your DEXA scores aren't that severe, only your femoral neck is slightly above the osteoporosis range. Take time to do some research so you are comfortable with your decision. Remember that bones change very slowly, so you have time to do this.

Also, after Evenity you will have to go back on a bisphosphonate to keep your gains. Since you already have GERD, oral Fosamax might aggravate that. There's Reclast infusions, so you will want to research them also.

These articles might be helpful: https://prospluscons.com/pros-and-cons-of-evenity/
https://melioguide.com/medications/evenity-a-physicians-perspective/
This article is titled: Forteo®, Tymlos® and Evenity®: How Much Do They Really Reduce Fracture Risk?
https://betterbones.com/bone-drugs/anabolic-treatment/

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@daisy17
Thank you so much for these articles. They are very helpful

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My age is 70, also I did try Prolia but only 1 shot b/c my jaw was cracking, thank you for articles

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I had a fracture with a lumbar spine T-score that was -1.6. So, T-scores aren’t always the best predictor of a fracture. And many people have osteoporosis and never fracture.

I would ask my endocrinologist to explain their thinking regarding starting you on Evenity, especially since you’ve never fractured. It could be they have a very good explanation for recommending it. It may also have to do with seeing the progression of deterioration of the outside of your bones.

The medications you’ve been on do not help you build new bone; they only slow down the breakdown of your old bone. They can also contribute to your bones becoming more brittle over time.

Since you have GERD, the medication you may be on to address it may have also contributed to bone loss as it impacts your ability to absorb calcium from your diet.

Only a guess on my part, but it sounds like your doctor wants you to build new bone and Evenity will help you do that.

Osteoporosis is a silent disease in that you may feel well until you fracture.

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Earlier I posted a comment with a link to Better Bones (Dr Susan Brown) about the bone building drugs Evenity, Tymlos and Forteo. I just watched it again and was surprised to learn that, although they build bone, their fracture prevention benefit is minimal. Dr Susan Brown said studies show those three drugs don't reduce hip fractures by any significant amount. They reduce vertebral fractures by 1-4%, meaning that 100 women have to take the drug to prevent 1-4 vertebral fractures. That appears to be a low benefit for a drug that can cost as much as $30,000 a year.

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@jdshep Thank you for your info. I appreciate your sharing details. This is what I'm afraid of, side effects that you can't control. Prayers for you.

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It has to be a personal decision. I was very leary too. After a lot of research I decided to stay on holiday for now. I also got a second opinion and my former doctor told me to get CTx labs done every 6 months to see the rate of bones being broken down. Below 250 is the good range. My last score 322 and doctor said that was ok. Oh my T scores -2.3 femoral neck. -2.7 spine and -.3 total hip.Hip has remained the same for years. Each of us is unique and at 83 , I am finding taking care of the body is a full time job. But I am aging out.

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Thank you for your info, I guess a second opinion is beneficial. Yes, taking care of body is a big job!

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Profile picture for daisy17 @daisy17

Earlier I posted a comment with a link to Better Bones (Dr Susan Brown) about the bone building drugs Evenity, Tymlos and Forteo. I just watched it again and was surprised to learn that, although they build bone, their fracture prevention benefit is minimal. Dr Susan Brown said studies show those three drugs don't reduce hip fractures by any significant amount. They reduce vertebral fractures by 1-4%, meaning that 100 women have to take the drug to prevent 1-4 vertebral fractures. That appears to be a low benefit for a drug that can cost as much as $30,000 a year.

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@daisy17 well that’s certainly disappointing and alarming.

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I would appreciate hearing from those of you taking the Evenity injection if you have experienced sudden weight gain. I’m approaching my 4th injection and have gained at least 5-7 lbs.!

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