Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Posted by dougs72 @dougs72, Jun 22, 2024

Has anyone ever been on Duloxetine (Cymbalta) for nerve pain? I've had 2 doctors push this on me. I know that the side effects can be terrible and getting off of it difficult as it requires titration. One time I remember taking one pill, and not liking the way it made me feel, so not taking any more, and still feeling the "weirdness" from it 2-3 days later. and that was only 30 mg Please pass along any experience or advice from this medication?

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cdammen | @cdammen | 2 days ago

I, too, have reacted negatively or not at all to many meds. Recently I discovered I had 0.0 activity of CYP2D6. In particular codeine has no effect and my body does not tolerate duloxetine and Metroprolol. I expect pharmacogenomics to be the future of medication—where we truly learn why meds work or do not work with the bodies we have.

ams | @ams | 1 day ago

In reply to @ohiogirl48 "I take Duloxetine for my fibromyalgia. The problem is, it's not going to be available much..." + (show)

@ohiogirl48 Why is duloxetine going away?

ohiogirl48 | @ohiogirl48 | 1 day ago

Express Scripts told me a few months ago it would be unavailable until further notice, but from reading all these posts, that isn't the case with everyone. I spoke with a pharmacist at Express Scripts today, and they told me that they haven't had it in stock since February. That seems silly since I've been receiving it since then, and I currently have half of a 90-day supply and a full 90-day supply left. Apparently, the supplier Express Scipts uses can no longer get it from the manufacturer. The pharmacist couldn't tell me why. They also told me I could get 90-day supplies from a retail pharmacy, so the retail pharmacy's supplier isn't having any trouble getting it. So, it looks like this is an Express Scripts issue only. Sorry for the confusion.