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Clobetasol propionate for lichen sclerosus

Posted by bushelbasket @bushelbasket, Apr 16 12:57pm

Does clobetasol propionate irritate any of you w/ lichen sclerosus? It seems to be making mine worse and my ob/gyn says she'll do a biopsy if I'm not better in 3 weeks. Any alternatives to suggest?

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strafer | @strafer | Apr 23 12:08pm

I've used Clobetesol for lichens planus and it was effective for decreasing the itch, but the effect is not a lasting one. The rash returns and remaining free is not a cure with Clobetesol.

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Mentor
Becky, Volunteer Mentor | @becsbuddy | Apr 23 4:49pm

@bushselbasket Welcome to Mayo Clinic Connect! Glad to have you here.

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thisfatoldlady | @thisfatoldlady | Apr 24 10:04am

I thought I had lichen sclerosus, but instead it was diagnosed as some kind of dermatitis with precancerous cells. I was prescribed Clobetesol for the itch. It helped - sort of, but not consistently. My doctor took a biopsy, that mostly removed the tissue in that area - however, it has come back - just not as itchy. I only use the Clobetesol when the itching becomes a problem. I just don't think it's highly effective, just helpful - and it's one of those things they want you to use whether you have symptoms or not.

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